HIV-positive women in Australia explain their use and non-use of antiretroviral therapy in preventing mother-to-child transmission

AIDS Care ◽  
2010 ◽  
Vol 23 (5) ◽  
pp. 578-584 ◽  
Author(s):  
Karalyn McDonald ◽  
Maggie Kirkman
Keyword(s):  
Antiretroviral Therapy ◽  
Hiv Positive ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Hiv Positive Women ◽  
Mother To Child

scholarly journals HIV-Positive Women Taking Lifelong Antiretroviral Therapy Report Better Adherence Than Women Taking Short-Course Prophylaxis During and After Pregnancy Under PMTCT Program Option A in Lusaka, Zambia

2017 ◽  
Vol 6 (1) ◽  
pp. 27 ◽  
Author(s):  
Karen Marie Hampanda, PhD, MPH ◽  
Lisa L. Abuogi, MD, MS ◽  
Yusuf Ahmed, MPH, BM
Keyword(s):  
Antiretroviral Therapy ◽  
Sub Saharan Africa ◽  
Hiv Positive ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Cross Sectional ◽  
Therapy Regimen ◽  
Hiv Positive Women ◽  
Short Course ◽  
Mother To Child

Background and Objectives: HIV-positive women’s adherence to antiretrovirals is critical for prevention of mother-to-child transmission. We aimed to establish if mothers taking triple lifelong antiretroviral therapy report higher adherence compared to mothers taking short-course prophylaxis under Option A in Lusaka, Zambia.Methods: In this clinic-based cross-sectional study, we interviewed 320 HIV-positive mothers at a large public health facility in Lusaka in 2014. Participants reported adherence using a visual analog scale. Multiple logistic regression models were used to determine the adjusted odds of adherence by mother’s prescribed regimen.Results: Women taking lifelong triple antiretroviral therapy report higher adjusted odds of adherence during pregnancy, postpartum, and to giving the infant prophylaxis compared to women to women taking short-course prophylaxis.Discussion: Women on lifelong therapy may have better adherence compared to women on short course prophylaxis because they knew their positive status for longer or were symptomatic with HIV-related disease. The lifelong therapy regimen may be easier for women to follow, particularly because they are required to give the infant prophylaxis for a shorter duration of time.Conclusions and Global Health Implications: Our results indicate that lifelong triple antiretroviral therapy has the potential to promote better drug adherence during and after pregnancy among women living with HIV in sub-Saharan Africa, compared to short-course antiretroviral regimens.Key words: HIV-positive Women • Prevention of Mother-to-Child Transmission • Antiretroviral Therapy • Adherence • Zambia • Option A • PMTCT • ARTCopyright © 2017 Hampanda et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

UNMET NEED FOR CONTRACEPTION AMONG HIV-POSITIVE WOMEN IN LESOTHO AND IMPLICATIONS FOR MOTHER-TO-CHILD TRANSMISSION

2009 ◽  
Vol 41 (2) ◽  
pp. 269-278 ◽  
Author(s):  
TIMOTHY ADAIR
Keyword(s):  
Family Planning ◽  
Unmet Need ◽  
Hiv Positive ◽  
Mother To Child Transmission ◽  
Hiv Status ◽  
Child Transmission ◽  
Childbearing Age ◽  
Hiv Positive Women ◽  
Mother To Child ◽  
Unmet Need For Contraception

SummaryIn Lesotho, the risk of mother-to-child-transmission (MTCT) of HIV is substantial; women of childbearing age have a high HIV prevalence rate (26·4%), low knowledge of HIV status and a total fertility rate of 3·5 births per woman. An effective means of preventing MTCT is to reduce unwanted fertility. This paper examines the unmet need for contraception to limit and space births among HIV-positive women in Lesotho aged 15–49 years, using the 2004 Lesotho Demographic and Health Survey. HIV-positive women have their need for contraception unmet in almost one-third of cases, and multivariate analysis reveals this unmet need is most likely amongst the poor and amongst those not approving of family planning. Urgent action is needed to lower the level of unmet need and reduce MTCT. A constructive strategy is to improve access to family planning for all women in Lesotho, irrespective of HIV status, and, more specifically, integrate family planning with MTCT prevention and voluntary counselling and testing services.

scholarly journals HIV Mother-to-Child Transmission, Mode of Delivery, and Duration of Rupture of Membranes: Experience in the Current Era

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Siobhan Mark ◽  
Kellie E. Murphy ◽  
Stanley Read ◽  
Ari Bitnun ◽  
Mark H. Yudin
Keyword(s):  
Mode Of Delivery ◽  
Case Series ◽  
Vaginal Birth ◽  
Hiv Positive ◽  
Entire Group ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Viral Loads ◽  
Hiv Positive Women ◽  
Mother To Child

Objective. To evaluate whether the length of time of rupture of membranes (ROM) in optimally managed HIV-positive women on highly active antiretroviral therapy (HAART) with low viral loads (VL) is predictive of the risk of mother to child transmission (MTCT) of the human immunodeficiency virus (HIV).Study Methods. A retrospective case series of all HIV-positive women who delivered at two academic tertiary centers in Toronto, Canada from January 2000 to November 2010 was completed.Results. Two hundred and ten HIV-positive women with viral loads <1,000 copies/ml delivered during the study period. VL was undetectable (<50 copies/mL) for the majority of the women (167, 80%), and <1,000 copies/mL for all women. Mode of delivery was vaginal in 107 (51%) and cesarean in 103 (49%). The median length of time of ROM was 0.63 hours (range 0 to 77.87 hours) for the entire group and 2.56 hours (range 0 to 53.90 hours) for those who had a vaginal birth. Among women with undetectable VL, 90 (54%) had a vaginal birth and 77 (46%) had a cesarean birth. Among the women in this cohort there were no cases of MTCT of HIV.Conclusions. There was no association between duration of ROM or mode of delivery and MTCT in this cohort of 210 virally suppressed HIV-positive pregnant women.

scholarly journals Predictors of Unmet Need for Family Planning among HIV Positive Women in Care in Federal Teaching Hospital Gombe, Nigeria

2020 ◽  
pp. 26-33
Author(s):  
A. Mohammed ◽  
D. Chiroma ◽  
C. H. Laima ◽  
M. A. Danimoh ◽  
P. A. Odunze
Keyword(s):  
Family Planning ◽  
Unmet Need ◽  
Hiv Care ◽  
Hiv Positive ◽  
P Value ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Hiv Positive Women ◽  
History Of ◽  
Mother To Child

Background: Elimination of mother-to-child transmission (EMTCT) of Human Immunodeficiency Virus (HIV) requires adequate and continuous use of family planning commodities among women of reproductive age. This can be made possible by reducing the proportion of HIV positive women with unmet need for family planning. The study aims to determine the factors associated with having unmet need among women in HIV care. Methods: A cross sectional study was conducted using an interviewer administered questionnaire to study 325 women on HIV care. Cluster sampling technique was used to select the study respondents from the clinic. Results: Less than half of the respondents (40%) were currently using family planning, 35% had unmet need for family planning with 53.6% having unmet need for spacing while 46.4% having unmet need for limiting. Women with no history of previous use of family planning were fifteen times more likely to have unmet need for family planning than those with history of previous use of family planning (p value <0.001, CI 2.511-15.770). Also women with more than five deliveries were eight times more likely to have unmet need for family planning (p value 0.004, CI 0.001-0.279) while women with 2-5 deliveries are four times likely to have unmet need for family planning (p value 0.035, CI 0.005-0.832). Conclusion: A high proportion of women receiving ART care still have unmet need for family planning despite incorporating this service in HIV care. It is therefore important to target high risk groups to reduce the proportion of women with unmet need for family planning which will invariable reduce mother to child transmission of HIV.

DOES KNOWLEDGE ABOUT ANTIRETROVIRAL THERAPY AND MOTHER-TO-CHILD TRANSMISSION AFFECT THE RELATIONSHIPS BETWEEN HIV STATUS AND FERTILITY PREFERENCES AND CONTRACEPTIVE USE? NEW EVIDENCE FROM NIGERIA AND ZAMBIA

2013 ◽  
Vol 46 (5) ◽  
pp. 580-599 ◽  
Author(s):  
AKINRINOLA BANKOLE ◽  
ANN E. BIDDLECOM ◽  
KUMBUTSO DZEKEDZEKE ◽  
JOSHUA O. AKINYEMI ◽  
OLUTOSIN AWOLUDE ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Contraceptive Use ◽  
Hiv Positive ◽  
Hiv Status ◽  
Child Transmission ◽  
Hiv Positive Women ◽  
Childbearing Desires ◽  
Living With Hiv ◽  
Mother To Child ◽  
Hiv Negative

SummaryThe increasing availability of antiretroviral therapy (ART) and drug regimens to prevent mother-to-child transmission (PMTCT) has probably changed the context of childbearing for people living with HIV. Using data from 2009–2010 community-based surveys in Nigeria and Zambia, this study explores whether women's knowledge about ART and PMTCT influences the relationship between HIV status and fertility preferences and contraceptive behaviour. The findings show that women living with HIV are more likely to want more children in Nigeria and to want to limit childbearing in Zambia compared with HIV-negative women. While there is no significant difference in contraceptive use by women's HIV status in the two countries, women who did not know their HIV status are less likely to use contraceptives relative to women who are HIV-negative. Knowledge about ART reduces the childbearing desires of HIV-positive women in Nigeria and knowledge about PMTCT increases desire for more children among HIV-positive women in Zambia, as well as contraceptive use among women who do not know their HIV status. The findings indicate that knowledge about HIV prevention and treatment services changes how living with HIV affects childbearing desires and, at least in Zambia, pregnancy prevention, and highlight the importance of access to accurate knowledge about ART and PMTCT services to assist women and men to make informed childbearing decisions. Knowledge about ART and PMTCT should be promoted not only through HIV treatment and maternal and newborn care facilities but also through family planning centres and the mass media.

scholarly journals Epidemiology of HIV Infection Among HIV-Exposed Infants, Nairobi County, Kenya, 2015

2020 ◽  
Vol 13 ◽  
pp. 117863372094886
Author(s):  
Anthony B Kiplagat ◽  
Carol Ngunu ◽  
Elvis Oyugi ◽  
James Ransom
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Turnaround Time ◽  
Hiv Positive ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Public Health Action ◽  
Hiv Exposed Infants ◽  
Hiv Exposed ◽  
Mother To Child

Objective: To characterize human immunodeficiency virus (HIV)-positive infants among HIV-exposed infants (HEIs) in Nairobi County for public health action. Methods: We conducted a retrospective review of records of HEIs’ HIV polymerase chain reaction (PCR) results in Nairobi County in 2015, excluding confirmatory PCR-positive results. HIV-exposed infant registry data were entered into Microsoft Excel and descriptive and associative statistics were calculated with OpenEpi software. Results: A total of 5802 HEI records were analyzed, with a median age of 4.5 (interquartile range, 8.5) months; 342 (5.9%) tested positive, 51% were female, and 4420 (76.2%) were seen at maternal and child health clinics. Standard highly active antiretroviral therapy intervention was given to 184 (60.3%) of the mothers of exposed infants, and 178 (53%) of the HIV-positive infants received active antiretroviral therapy. A total of 3464 (59.7%) HEIs had PCR done within the first 2 months, and 119 (3.4%) tested positive. The average turnaround time for PCR samples was 28 ± 22 days, and a total of 191 (3.3%) HIV-positive HEIs were exclusively breastfed for the first 6 months of life. Conclusion: The recorded mother-to-child transmission (MTCT) rate of 5.9% in Nairobi County is lower than the 2015 national rate, which suggests the Nairobi prevention of mother-to-child transmission efforts are moderately effective. However, results from this study show that Kenya will struggle to meet the MTCT 2020 target rate of <5%.

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