NUTRITIONAL STATUS OF INFANTS BASED ON FREQUENCY AND DIETARY DIVERSITY OF COMPLEMENTARY FEEDING

Background: In 2017, the prevalence of malnutrition in Indonesia was ranked 4­th among Southeast Asia countries. The nonoptimal complementary feeding is one of the reasons. The nonoptimal complementary feeding is associated with the prevalence of underweight and stunting in the children at the age 6-23 months. Complementary feeding pattern include frequency and dietary diversity. This study aims to investigate the relationship between complementary feeding pattern and nutritional status of infants at the age 7-12 months in the Kedungwaru Health Center, Tulungagung. Methods: This study used observational analytic and cross-sectional study design. The sample consisted of 71 mothers of the infants which were taken by total sampling. The variables of this study were complementary feeding pattern and nutritional status. This study also used a questionnaire and observation sheet. The Fisher Exact Test was used to analyse the data. Result: The results showed 88.7% of the infants have good nutritional status. There are 49.3% appropriate complementary feeding and 69% which applied various types of complementary feeding. The frequency of complementary feeding with the nutritional status of infants obtained p value 0.478 and the dietary diversity of complementary feeding with nutritional status obtained p value 0.102. Conclusions: There were no significant relation between the complementary feeding pattern and the nutritional status (weight-for-age) in infants at the age 7-12 months. Further research about other variables is needed.

PSVI-6 Effect of season on the feeding behaviour and kinetics of daily feed intake of high-prolific sows during lactation

Heat stress can cause changes in the feeding behaviour of lactating sows. The present study aimed to evaluate the impacts of season on the feeding behavior and kinetics of daily feed intake of modern high prolific sows under tropical conditions. A total of 80 high-prolific mixed parity sows divided into 10 batches of 8 sows each were used. Individual feeding behaviour was recorded during the ad libitum period (between d 1 and 23 of lactation), using an Automated Intelligent Feeder (AIF; Gestal Solo, Jyga Technology, Canada). Daily feed intake during lactation was affected by season (P < 0.001), and the feed intake was less during the hot season (5.66 vs. 7.23 g/d; Figure 1a). The daily ingestion time was less in the hot season (36.8 vs. 72.3 min/ d; P< 0.01) and the ingestion time per meal was also lower in the hot compared to the cool season (5.7 vs. 7.5 min/ meal; P < 0.05). The hot season showed a lower (P < 0.01) rate of daily intake when compared to the cool season (36.8 vs. 72.3 g/ min). Sows showed a higher diurnal feed intake (3,546 vs. 2,901 g/ d), whereas meal frequency was not affected (4.2 meals/ d, on average). Irrespective of the season, the nycthemeral pattern of feed intake peaked twice daily: between 0200 and 0900 h and between 1600 and 2000 h (Figure 1b).The present study confirms that lactating sows do not change much their feeding pattern according to season, meaning that they tend to keep the same feeding behaviour during both seasons, with a more pronounced intake between 0200 and 0900 am, approximately 80% of their total daily intake. Sows may not change feeding pattern according to season, but reduce significantly voluntary feed intake under hot climate conditions in order to reduce the thermal effect of feed.

Estimation of Genetic Parameters for Feeding Pattern Traits and Its Relationship to Feed Efficiency and Production Traits in Duroc Pigs

This study was conducted to estimate the genetic parameters of different feeding pattern traits, including average daily feed intake (ADFI), average occupation time per day (AOTD), average occupation time per visit (AOTV), average daily feeding rate (ADFR), average feeding rate per feeding visit (AFRV), average feed intake per feeding visit (AFIV), and average number of visits per day (ANVD), and their genetic relationship to production traits, such as on-test average daily gain (ADG), backfat thickness (BFT), loin muscle area (LMA), lean percentage (LP), and feed efficiency traits, such as feed conversion ratio (FCR) and five measures of residual feed intake (RFI1 to RFI5), in Duroc pigs (DD). The non-heritable common spatial pen effect was also estimated in all studied traits. The feeding pattern traits used in this study were derived from filtered feeding visits of 602 DD pigs. Using three animal models and the REML method, the genetic parameters revealed low to moderate heritability for ADFI (0.19 to 0.32) and AFIV (0.18 to 0.33), moderate heritability for ANVD (0.28 to 0.35) and AOTV (0.21 to 0.31), and high heritability for AOTD (0.73), ADFR (0.62 to 0.64), and AFRV (0.59 to 0.63). The addition of a common spatial pen effect in models 2 and 3 had a substantial impact, ranging from 8% to 23%, on the total variability of most feeding pattern traits, with the exception of AOTD, which only had a percentage variance of 0.30% due to the pen effect. The genetic and phenotypic correlation revealed that ADFI had consistent moderate to high genetic and phenotypic correlation with production and feed efficiency (FE) traits. However, selection against ADFI would negatively affect on-test ADG. Interestingly, the AOTD had no genetic correlation with ADG (0.04), low to moderate positive genetic correlation with FCR (0.27) and all RFI measures (0.24 to 0.33), and moderate negative correlation with LP (−0.39), indicating that selection for DD pigs with lower AOTD would not influence on-test ADG but may increase LP and improve feed efficiency by lowering FCR and all RFI measures. However, the corresponding phenotypic correlation of AOTD with production and feed efficiency traits was mostly weak, which can be attributed to the low residual or environmental correlation between these correlated traits. At the genetic level, the feeding pattern traits showed potential in improving feed efficiency and production traits. However, further studies are needed to evaluate their impact at phenotypic level.

The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity

Background Feeding rhythm disruption contributes to the development of obesity. The receptors of glucagon-like peptide-1 (GLP-1) are distributed in the wide regions of the brain. Among these regions, GLP-1 receptors (GLP-1R) are expressed in the dorsomedial hypothalamic nucleus (DMH) which are known to be associated with thermogenesis and circadian rhythm development. However, the physiological roles of GLP-1R expressing neurons in the DMH remain elusive. Methods To examine the physiological role of GLP-1R expressing neurons in the DMH, saporin-conjugated exenatide4 was injected into rat brain DMH to delete GLP-1R-positive neurons. Subsequently, locomotor activity, diurnal feeding pattern, amount of food intake and body weight were measured. Results This deletion of GLP-1R-positive neurons in the DMH induced hyperphagia, the disruption of diurnal feeding pattern, and obesity. The deletion of GLP-1R expressing neurons also reduced glutamic acid decarboxylase 67 and cholecystokinin A receptor mRNA levels in the DMH. Also, it reduced the c-fos expression after refeeding in the suprachiasmatic nucleus (SCN). Thirty percent of DMH neurons projecting to the SCN expressed GLP-1R. Functionally, refeeding after fasting induced c-fos expression in the SCN projecting neurons in the DMH. As for the projection to the DMH, neurons in the nucleus tractus solitarius (NTS) were found to be projecting to the DMH, with 33% of those neurons being GLP-1-positive. Refeeding induced c-fos expression in the DMH projecting neurons in the NTS. Conclusion These findings suggest that GLP-1R expressing neurons in the DMH may mediate feeding termination. In addition, this meal signal may be transmitted to SCN neurons and change the neural activities.

Abstract MP14: The Effect Of Time-restricted Feeding On 24-hour Ambulatory Blood Pressure: Results From The Time-restricted Intake Of Meals (TRIM) Study

Introduction: Some studies suggest that time-restricted feeding may decrease blood pressure (BP), but the current evidence is inconclusive. Objective: To determine the effect of a time-restricted feeding pattern compared to a usual feeding pattern on ambulatory 24-hour BP in adults. Hypothesis: An isocaloric, time-restricted feeding pattern will lower 24-hour BP more than an isocaloric usual feeding pattern over 12 weeks. Methods: Forty-one persons with prediabetes (HbA1c 5.7-6.9%) and obesity (BMI 30-50 kg/m 2 ) were randomized to consume 80% of their total calories before 1 pm (i.e., time-restricted feeding) or more than 50% of their calories after 5 pm (i.e., usual feeding) with identical macronutrient content. We used ambulatory BP monitoring to measure BP over 24-hours at baseline and 12-weeks. Outcomes of interest were mean systolic and diastolic 24-hr, daytime (7 am - 11 pm), and nighttime (11 pm - 7 am) BP. To examine the difference in BP patterns between time-restricted feeding and usual feeding pattern groups in change in BP outcomes from baseline to 12 weeks, we used linear mixed-effects regression models with participant-specific random intercepts and fixed effects for visit and intervention group. To assess whether feeding patterns affected BP levels over the 12 week intervention period, we tested whether there was an intervention-by-time interaction. Results: Thirty-five adults (mean age 60.4 years; 91% female, 91% African American) had sufficient data. We found reductions from baseline in systolic and diastolic BP for both groups for the 24-hour, daytime, and nighttime periods. The decrease in BP was larger in the usual feeding pattern group compared to the time-restricted feeding group (Table). Conclusion: Time-restricted feeding may attenuate the effect of a healthy isocaloric diet on BP compared to typical feeding patterns, and at this time, should not be recommended as a way to lower BP more than simply adopting a healthy diet.

Pengaruh Pakan terhadap Status Fisiologi Kambing Kacang (Capra aegragus hircus) dengan Pola Pemeliharaan Insentif di Daerah Lahan Kering

The aim of this research was to determine the ratio between the provision of Moringa to the physiological status (body temperature) of female goats. This research was conducted in the dryland field laboratory of the Nusa Cendana University, using 16 adult female goats, with a range of 6-7 months and body weight ranging from 10-12 kg. Goats were divided into 2 groups, namely groups using ammoniated grass and concentrate formulations combined with Moringa and without Moringa. The results showed that the body temperature of kacang goats that placed in individual cages with incentive maintenance patterns with cage adaptation for approximately 45 days, with a feeding pattern with no moringa concentrate and with moringa that given in the morning ranged from 38.8-39.0˚C and 38.7-39.2˚C. While in the afternoon, ranging from 38.7-39.2˚C and 38.7-39.0˚C. The conclusion is this body temperature was still in the normal range of body temperature for young female kacang goats.