Effect of the Route of Administration on the Induction of Cytogenetic Damage and DNA Adducts in Peripheral Blood Lymphocytes of Rats and Mice by Polycyclic Aromatic Hydrocarbons

2002 ◽  
Vol 22 (3-4) ◽  
pp. 841-851
Author(s):  
Andrew D. Kligerman ◽  
Garret B. Nelson ◽  
Jeffrey A. Ross ◽  
Gregory L. Erexson
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Dna Adducts ◽  
Aromatic Hydrocarbons ◽  
Peripheral Blood ◽  
Peripheral Blood Lymphocytes ◽  
Route Of Administration ◽  
Cytogenetic Damage ◽  
Blood Lymphocytes ◽  
Polycyclic Aromatic ◽  
Rats And Mice

DNA Adducts Formed bysynDihydrodiol Epoxides of Polycyclic Aromatic Hydrocarbons

1994 ◽  
Vol 6 (1-4) ◽  
pp. 87-93 ◽  
Author(s):  
Jan Szeliga ◽  
Bruce D. Hilton ◽  
Hongmee Lee ◽  
Ronald G. Harvey ◽  
Anthony Dipple
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Dna Adducts ◽  
Aromatic Hydrocarbons ◽  
Polycyclic Aromatic

scholarly journals Association of polycyclic aromatic hydrocarbons in moss with blood biomarker among nearby residents in Portland, Oregon

2021 ◽  
Author(s):  
Igor Burstyn ◽  
Geoffrey H. Donovan ◽  
Yvonne L. Michael ◽  
Sarah Jovan
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Air Quality ◽  
Dna Adducts ◽  
Aromatic Hydrocarbons ◽  
Human Health Risk ◽  
Monitoring Methods ◽  
Wood Fire ◽  
Individual Determinants ◽  
Polycyclic Aromatic ◽  
Environmental Air

Polycyclic aromatic hydrocarbons (PAHs) are a component of air pollutants that are costly to measure using traditional air-quality monitoring methods. We used an epiphytic bio-indicator (moss genus: Orthotrichum) to cost-effectively evaluate atmospheric deposition of PAHs in Portland, Oregon in May 2013. However, it is unclear if measurements derived from these bioindicators are good proxies for human exposure. To address this question, we simultaneously, measured PAH-DNA adducts in blood samples of non-smokers residing close to the sites of moss measurements. We accounted for individual determinants of PAH uptake that are not related to environmental air quality through questionnaires, e.g., wood fires, consumption of barbecued and fried meats. Correlation and linear regression (to control for confounders from the lifestyle factors) evaluated the associations. We did not observe evidence of an association between PAH levels in moss and PAH-DNA adducts in blood of nearby residents, but higher level of adduct were evident in those who used wood fire in their houses in the last 48 hours. It remains to be determined whether bio-indicators in moss can be used for human health risk assessment.

scholarly journals Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites

1999 ◽  
Vol 20 (10) ◽  
pp. 1885-1891 ◽  
Author(s):  
Victor J. Melendez-Colon ◽  
Andreas Luch ◽  
Albrecht Seidel ◽  
William M. Baird
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Dna Adducts ◽  
Aromatic Hydrocarbons ◽  
Cancer Initiation ◽  
Polycyclic Aromatic

scholarly journals Prenatal Exposure to Polycyclic Aromatic Hydrocarbons, Benzo[a]pyrene–DNA Adducts, and Genomic DNA Methylation in Cord Blood

2012 ◽  
Vol 120 (5) ◽  
pp. 733-738 ◽  
Author(s):  
Julie B. Herbstman ◽  
Deliang Tang ◽  
Deguang Zhu ◽  
Lirong Qu ◽  
Andreas Sjödin ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Polycyclic Aromatic Hydrocarbons ◽  
Cord Blood ◽  
Prenatal Exposure ◽  
Dna Adducts ◽  
Aromatic Hydrocarbons ◽  
Genomic Dna ◽  
Polycyclic Aromatic
Sign in / Sign up

Export Citation Format

Share Document