AbstractA rapid and an efficient one-pot method for the synthesis of quinoxalines catalysed by ZnO-beta zeolite at room temperature is described. This environmentally benign method provides several advantages over methods that are currently employed such as a simple work-up, mild reaction conditions, good to excellent yields, and a process to recover and reuse the catalyst for several cycles with consistent activity.
An efficient method for the synthesis of 1,2,4,5-tetra substituted imidazoles usingK7Na3P2W18Cu4O68as catalyst is reported. This four-component condensation of benzil, aldehydes, amines, and ammonium acetate proceeds under solvent-free conditions. The catalyst is handling and recoverable.
A new catalytic strategy for the one-pot synthesis of N-sulfonylamidines is described. The cationic copper(I) complexes were found to be highly active and efficient under mild conditions in air and in the absence of solvent. A copper acetylide is proposed as key intermediate in this transformation.
Treatment of nucleoside phosphoropiperidates with 0.5 equiv of water in the presence of 4,5-dicyanoimidazole (DCI) provides an efficient method for one-pot synthesis of symmetrical P1,P2-dipyrimidine-nucleoside diphosphates under mild conditions.
ZnO-beta zeolite mediated simple and efficient method for the one-pot synthesis of quinoxaline derivatives at room temperature