SOLID-PHASE EXTRACTION AND HPLC ASSAY OF NICOTINE AND COTININE IN PLASMA AND BRAIN

2002 ◽  
Vol 12 (1) ◽  
pp. 45-58 ◽  
Author(s):  
Ralph Dawson Jr ◽  
S. M. Messina ◽  
C. Stokes ◽  
S. Salyani ◽  
N. Alcalay ◽  
...  
2002 ◽  
Vol 12 (1) ◽  
pp. 45-58 ◽  
Author(s):  
Ralph Dawson ◽  
S. M. Messina ◽  
C. Stokes ◽  
S. Salyani ◽  
N. Alcalay ◽  
...  

1997 ◽  
Vol 16 (1) ◽  
pp. 47-55 ◽  
Author(s):  
William W. Bullen ◽  
David T. Rossi ◽  
Keith L. Hoffman ◽  
Ajit Suri ◽  
Chetan D. Lathia

2004 ◽  
Vol 24 (5) ◽  
pp. 511-514 ◽  
Author(s):  
Julie Sunderland ◽  
Andrew M. Lovering ◽  
Caroline M. Tobin ◽  
Alasdair P. MacGowan ◽  
John M. Roe ◽  
...  

Author(s):  
J L Rudy ◽  
J C Argyle ◽  
N Winick ◽  
P Van Dreal

A convenient HPLC assay, which allows for the simultaneous measurement in extracellular fluids of 6-mercaptopurine and four of its metabolites, 6-thioguanine, 6-mercaptopurine riboside, 6-thioxanthine and 6-thiouric acid is described. Solid phase extraction allows for the clean isolation of analytes from plasma, urine or cerebrospinal fluid. The simultaneous determination of 6-mercaptopurine and some of its major metabolites in extracellular fluids may contribute to the monitoring of patient compliance, bioavailability, and individual variation in metabolism and absorption.


2002 ◽  
Vol 24 (6) ◽  
pp. 751-756 ◽  
Author(s):  
Erin Connor ◽  
Masayuki Sakamoto ◽  
Kenichi Fujikawa ◽  
Terence Law ◽  
Nader Rifai

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