Effect of Chronic Ethanol Feeding on Oxysterols in Rat Liver

2002 ◽  
Vol 36 (6) ◽  
pp. 661-666 ◽  
Author(s):  
Koichi Ariyoshi ◽  
Junko Adachi ◽  
Migiwa Asano ◽  
Yasuhiro Ueno ◽  
Rajkumar Rajendram ◽  
...  
Keyword(s):  
Rat Liver ◽  
Chronic Ethanol ◽  
Ethanol Feeding

Effects of prolonged ethanol feeding on methionine metabolism in rat liver

1987 ◽  
Vol 65 (3) ◽  
pp. 230-233 ◽  
Author(s):  
Anthony J. Barak ◽  
Harriet C. Beckenhauer ◽  
Dean J. Tuma ◽  
Shahrokh Badakhsh
Keyword(s):  
Rat Liver ◽  
Time Course ◽  
Chronic Ethanol ◽  
Synthetase Activity ◽  
Methionine Metabolism ◽  
Tissue Levels ◽  
Ethanol Feeding ◽  
Time Course Study ◽  
Betaine Homocysteine Methyltransferase ◽  
Homocysteine Methyltransferase

Pairs of rats were fed control and alcohol liquid diets for periods of 1, 2, 3, and 4 months. The animals were then killed, and their livers analyzed for betaine, S-adenosylmethionine (SAM), methionine synthetase activity, and betaine–homocysteine methyltransferase (BHMT) activity. The results of this time-course study showed that chronic ethanol feeding inhibited the activity of the methionine synthetase throughout the study, but increased the activity of BHMT and lowered betaine levels. These data suggest that the rat, because of its ability to produce betaine from choline, has the capacity to compensate for the ethanol-induced impairment of methionine synthetase and maintain vital tissue levels of SAM over prolonged periods of time via an adaptive increase in BHMT activity.

Increase in lipoperoxides and prolyl hydroxylase activity in rat liver following chronic ethanol feeding

1990 ◽  
Vol 40 (5) ◽  
pp. 1015-1019 ◽  
Author(s):  
Yamada Sadako ◽  
Yamada Minoru ◽  
Murawaki Yoshikazu ◽  
Hirayama Chisato
Keyword(s):  
Rat Liver ◽  
Prolyl Hydroxylase ◽  
Chronic Ethanol ◽  
Hydroxylase Activity ◽  
Ethanol Feeding
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