Lipid peroxidation and antioxidant defense systems in rat liver after chronic ethanol feeding

Hepatology ◽  
1989 ◽  
Vol 10 (5) ◽  
pp. 815-821 ◽  
Author(s):  
Tateo Kawase ◽  
Shinzo Kato ◽  
Charles S. Lieber
Keyword(s):  
Lipid Peroxidation ◽  
Rat Liver ◽  
Antioxidant Defense ◽  
Chronic Ethanol ◽  
Defense Systems ◽  
Ethanol Feeding ◽  
Antioxidant Defense Systems

Spaceflight Downregulates Antioxidant Defense Systems in Rat Liver

1998 ◽  
Vol 24 (2) ◽  
pp. 385-390 ◽  
Author(s):  
J. Hollander ◽  
M. Gore ◽  
R. Fiebig ◽  
R. Mazzeo ◽  
S. Ohishi ◽  
...  
Keyword(s):  
Rat Liver ◽  
Antioxidant Defense ◽  
Defense Systems ◽  
Antioxidant Defense Systems

scholarly journals Changes in Bone Metabolism and Antioxidant Defense Systems in Menopause-Induced Rats fed Bran Extract from Dark Purple Rice (Oryza sativa L. Cv. Superjami)

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 2926
Author(s):  
Soo Im Chung ◽  
Su Noh Ryu ◽  
Mi Young Kang
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Bone Loss ◽  
Bone Metabolism ◽  
Rice Bran ◽  
Antioxidant Defense ◽  
Control Group ◽  
Defense Systems ◽  
Antioxidant Defense Systems ◽  
And Oxidative Stress

Menopause is a matter of concern for women’s health due to a deficiency of female hormones; additionally, reactive oxygen species and aging can cause osteoporosis. Food becomes increasingly interesting as a menopausal woman’s alternative to hormone therapy. The effects of ethanol extracts from dark purple Superjami rice bran on bone metabolism and antioxidant defense systems in menopause-induced animal models were evaluated. Female rats underwent sham surgery or were ovariectomized to induce a menopause-like state. Rats were divided into a sham control group (SHAM), an ovariectomized control group (OVX), and an ovariectomized grou supplemented with Superjami rice bran extract group (OVX-S) and fed for 8 weeks. The OVX groups exhibited significantly more weight gain, amounts of bone turnover biochemical markers (alkaline phosphatase, osteocalcin, and C-terminal telopeptide), bone loss, lipid-peroxidation and oxidative stress than the SHAM group. However, Superjami bran extract added to the diet resulted in a significant reduction in body weight and lipid peroxidation, as well as enhanced bone metabolism and antioxidant enzyme activities, in ovariectomized rats. These results propound that extracts from Superjami rice bran have therapeutic potentiality against bone loss and oxidative stress in menopause-induced states and will be useful in preventing postmenopausal osteoporosis and oxidative damage.

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