The paper deals with safe communication between members of the Police of the Czech Republic and persons under the influence of narcotic drugs and psychotropic substances. The task of police officers is to maintain public order and monitor and investigate crime. Police officers are front line actors, addressing public crisis situations. They are increasingly confronted with people under the influence of narcotic drugs and psychotropic substances. When investigating crime, they collect information through interrogating suspects, the accused, witnesses and victims who abuse substances. The strategies employed by police officers in interrogating, and communicating with, these people is a key part of their work.