Systematic review of cochlear implantation in adults with asymmetrical hearing loss

This systematic review of the literature reveals which preoperative factors affect sequential cochlear implantation outcomes in adults. The findings can help health care professionals provide evidence-based advice on the expected benefits from a second cochlear implant (CI). We searched PubMed, EMBASE, and the Cochrane database from November 1977 to August 26, 2017, using the terms “sequential cochlear implantation”; the most frequently cited predictors for unilateral cochlear implantation performance and other potential predictors for sequential implantation outcome; and “speech perception,” “localization” as well as synonyms of all of the above. Ten studies were included. The effects of age, duration of hearing loss, time between implantations, preoperative hearing, etiology of hearing loss, hearing aid use and duration of follow-up on sequential cochlear implantation performance were studied. The literature has shown that duration of deafness, age at onset of deafness, etiology of hearing loss, and preoperative speech perception score are (inversely) related to unilateral cochlear implantation outcome in adults. One would expect that these factors would also affect sequential bilateral implantation outcome. However, the best available evidence to date shows that advanced age, a long duration of deafness, or a long interval between implantations should not be considered negative factors when considering sequential bilateral cochlear implantation.

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488 Anatomical and Audiological Considerations in Branchio-otic/Branchio-oto-renal Syndrome: A Systematic Review and Narrative Synthesis

British Journal of Surgery ◽

10.1093/bjs/znab134.560 ◽

2021 ◽

Vol 108 (Supplement_2) ◽

Author(s):

K Biggs ◽

G Crundwell ◽

C Metcalfe ◽

J Muzaffar ◽

P Monksfield ◽

...

Keyword(s):

Systematic Review ◽

Hearing Loss ◽

Hearing Aids ◽

Cochlear Implantation ◽

Middle Ear Surgery ◽

Narrative Synthesis ◽

Renal Anomalies ◽

Anatomical Variants ◽

Long Term Follow Up ◽

Ear Anomalies

Abstract Introduction Branchio-otic/ Branchio-oto-renal syndrome (BO/BOR) is a rare autosomal dominant condition characterised by hearing loss, branchiogenic and renal anomalies. Anatomical variants, audiological outcomes and optimal management are considered. Method Systematic review and narrative synthesis. Databases searched: Medline, Pubmed, Embase, Web of Science, Cochrane Collection and ClinicalTrials.gov. No limits placed on year of publication. Results Searches identified 379 articles. Of these, 64 studies met the inclusion criteria, reporting outcomes in 503 patients from at least 104 families. In 308 patients hearing loss was categorised as sensorineural (29%), conductive (20%) and mixed (51%). Hearing outcomes were variable in terms of onset, pattern, and severity, ranging from mild to profound deafness. 43% patients presented with inner ear anomalies, 35% had middle and 36% had external ear abnormalities. In 44 studies, 58 ear operations were described. Mixed outcomes were reported in patients managed with hearing aids or middle ear surgery; however successful cochlear implantation was described in all five cases. Conclusions The anatomical and audiological profiles of patients with BO/BOR are variable. Cochlear implantation outcomes were good however the studies lacked long-term follow-up. Given the range of anatomical variants, management decisions should be made on an individual basis including full audiological and radiological assessment.

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