Health-state utility estimates for health technology assessment: a review of the manufacturers’ submissions to the French National Authority for Health

2017 ◽  
Vol 17 (5) ◽  
pp. 489-494 ◽  
Author(s):  
Françoise F. Hamers ◽  
Salah Ghabri ◽  
Catherine Le Gales
2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1411.2-1411
Author(s):  
D. Rojas-Gualdrón ◽  
J. C. Diaz-Coronado ◽  
D. Hernandez-Parra ◽  
Y. Durango-Durango ◽  
R. Pined ◽  
...  

Background:As the basis for quality-adjusted life years (QALYs) calculation, health state utilities are essential for health technology assessment and economic evaluation.Objectives:To provide a reference value set of health state utility for patients with rheumatoid arthritis.Methods:A cross-sectional study was conducted in 1,545 patients diagnosed with rheumatoid arthritis. Disease activity was evaluated with the DAS-28 score. Health state utility (HSU) was estimated with the EUROQOL-5D-3L, using as reference the Spanish-speaking Hispanic predicted preference weights for 243 EQ-5D health states. Mean HSU differences were analyzed with the generalized linear model. A p-value <0.05 was considered statistically significant.Results:Patients mean age was 58.2 years (SD = 12.5), 82.4% were female. Disease activity was high in 137 (8.9%), moderate in 305 (19.7%) and low in 231 (56.4%) patients; 872 (56.4%) patients were in remission. HSU differed significantly by sex age and disease activity. Figures 1a (women) and 1b (men) shows the HSU by age and disease activity.Figure 1.Health State utilities by sex, age and disease activityConclusion:The way patients value different health states according to their sex, age and disease activity must be considered in health technology assessment and economic evaluations of interventions for rheumatoid arthritis patients. We provide a reference set for Latin-American patients.References:[1]Zarate V, Kind P, Chuang L-H. Hispanic Valuation of the EQ-5D Health States: A Social Value Set for Latin Americans. Value in Health. 2008;11(7):1170-7.Disclosure of Interests:None declared


Author(s):  
Marian Sorin Paveliu ◽  
Elena Olariu ◽  
Raluca Caplescu ◽  
Yemi Oluboyede ◽  
Ileana-Gabriela Niculescu-Aron ◽  
...  

Objective: To provide health-related quality of life (HRQoL) data to support health technology assessment (HTA) and reimbursement decisions in Romania, by developing a country-specific value set for the EQ-5D-3L questionnaire. Methods: We used the cTTO method to elicit health state values using a computer-assisted personal interviewing approach. Interviews were standardized following the most recent version of the EQ-VT protocol developed by the EuroQoL Foundation. Thirty EQ-5D-3L health states were randomly assigned to respondents in blocks of three. Econometric modeling was used to estimate values for all 243 states described by the EQ-5D-3L. Results: Data from 1556 non-institutionalized adults aged 18 years and older, selected from a national representative sample, were used to build the value set. All tested models were logically consistent; the final model chosen to generate the value set was an interval regression model. The predicted EQ-5D-3L values ranged from 0.969 to 0.399, and the relative importance of EQ-5D-3L dimensions was in the following order: mobility, pain/discomfort, self-care, anxiety/depression, and usual activities. Conclusions: These results can support reimbursement decisions and allow regional cross-country comparisons between health technologies. This study lays a stepping stone in the development of a health technology assessment process more driven by locally relevant data in Romania.


2009 ◽  
Vol 25 (S1) ◽  
pp. 108-111 ◽  
Author(s):  
Caroline Weill ◽  
David Banta

Objectives:The aim of this study was to describe the history of health technology assessment (HTA) in France.Methods:The approach was a descriptive review done by people who have been very much involved in this history.Results:The interest in HTA and evaluation as a tool for health decision making goes back to the 1970s in France. During the 1980s, there were several attempts to develop a national HTA agency, which finally came to fruition with the development of the Agence Nationale de l'Evaluation Medicale (ANDEM) in 1989. ANDEM's main success, perhaps, was in making HTA known in France by developing its own assessments, writing and validating appropriate methodologies for assessing medical technology and medical practices, and by organizing in France the development of programs of consensus development conferences, which the ANDEM either organized itself or supported and validated. In the mid-1990s, the mandate of ANDEM was extended to hospital accreditation and the agency's name was changed to Agence Nationale d'Accreditation et d'Evaluation en Sante (ANAES). Finally, in 2005, the National Authority for Health (HAS) was formed to consolidate efforts to centralize the programs of HTA, aiming at helping decision making regarding reimbursement and pricing, in one agency and to define the optimal use of health technology in France.Conclusions:HTA has become a strong influence in the healthcare system in France. These developments may be considered rather typical of the approach to public policy questions in France, where regulation is more in use than in other countries (at least in the healthcare field). At the same time, this approach has made lobbying and other attempts to influence decisions common as well, so one might say that HTA is more politicized than in some other countries in Europe.


2008 ◽  
Vol 19 (4) ◽  
pp. 253-269 ◽  
Author(s):  
Sabine Heel ◽  
Sonja Fischer ◽  
Stefan Fischer ◽  
Tobias Grässer ◽  
Ellen Hämmerling ◽  
...  

Zunächst führt dieser Artikel in die wesentlichen Begrifflichkeiten und Zielstellungen der Versorgungsforschung ein. Er befasst sich dann mit der Frage, wie die einzelnen Teildisziplinen der Versorgungsforschung, (1) die Bedarfsforschung, (2) die Inanspruchnahmeforschung, (3) die Organisationsforschung, (4) das Health Technology Assessment, (5) die Versorgungsökonomie, (6) die Qualitätsforschung und zuletzt (7) die Versorgungsepidemiologie konzeptionell zu fassen sind, und wie sie für neuropsychologische Anliegen ausformuliert werden müssen. In diesem Zusammenhang werden die in den einzelnen Bereichen jeweils vorliegenden versorgungsrelevanten Studienergebnisse referiert. Soweit es zulässig ist, werden Bedarfe für die Versorgungsforschung und Versorgungspraxis in der Neurorehabilitation daraus abgeleitet und Anregungen für die weitere empirische Forschung formuliert. Der Artikel bezieht sich – entsprechend seines Anliegens – ausschließlich auf Studien, die sich mit der Situation der deutschen Neurorehabilitation befassen.


Sign in / Sign up

Export Citation Format

Share Document