Second trimester cerebroplacental ratio versus umbilicocerebral ratio for the prediction of adverse perinatal outcomes

2021 ◽  
pp. 1-7
Author(s):  
Mae-Lan Winchester ◽  
Noria McCarther ◽  
Dominic Cancino ◽  
Sharon Fitzgerald ◽  
Marc Parrish
Keyword(s):  
Perinatal Outcomes ◽  
Second Trimester ◽  
Cerebroplacental Ratio ◽  
Adverse Perinatal Outcomes ◽  
Ratio Versus

226 Second trimester cerebroplacental ratio as a predictor of adverse perinatal outcomes

2021 ◽  
Vol 224 (2) ◽  
pp. S149-S150
Author(s):  
Mae-Lan Winchester ◽  
Noria McCarther ◽  
Dominic Cancino ◽  
Sharon Fitzgerald ◽  
Marc Parrish
Keyword(s):  
Perinatal Outcomes ◽  
Second Trimester ◽  
Cerebroplacental Ratio ◽  
Adverse Perinatal Outcomes

scholarly journals Predicting intrapartum fetal compromise at term using the cerebroplacental ratio and placental growth factor levels (PROMISE) study: randomised controlled trial protocol

BMJ Open ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. e022567 ◽  
Author(s):  
Helen Sherrell ◽  
Vicky Clifton ◽  
Sailesh Kumar
Keyword(s):  
Growth Factor ◽  
Randomised Controlled Trial ◽  
Screening Test ◽  
Controlled Trial ◽  
Perinatal Outcomes ◽  
Placental Growth Factor ◽  
Cerebroplacental Ratio ◽  
Adverse Perinatal Outcomes ◽  
Randomised Controlled ◽  
Fetal Compromise

IntroductionIntrapartum complications are a major contributor to adverse perinatal outcomes, including stillbirth, hypoxic–ischaemic brain injury and subsequent longer term disability. In many cases, hypoxia develops as a gradual process due to the inability of the fetus to tolerate the stress of parturition suggesting reduced fetoplacental reserve before labour commences. The fetal cerebroplacental ratio (CPR) is an independent predictor of intrapartum fetal compromise, poor acid base status at birth and of neonatal unit admission at term. Similarly, circulating maternal levels of placental growth factor (PlGF) are lower in pregnancies complicated by placental dysfunction. This paper outlines the protocol for the PROMISE Study, which aims to determine if the introduction of a prelabour screening test for intrapartum fetal compromise combining the CPR and maternal PlGF level results in a reduction of adverse perinatal outcomes.Methods and analysisThis is a single-site, non-blinded, individual patient randomised controlled trial of a screening test performed at term, combining the fetal CPR and maternal serum PlGF. Women with a singleton, non-anomalous pregnancy will be recruited after 34 weeks’ gestation and randomised to either receive the screening test or not. Screened pregnancies determined to be at risk will be recommended induction of labour. Demographic, obstetric history and antenatal data will be collected at enrolment, and perinatal outcomes will be recorded after delivery. Relative risks and 95% CIs will be reported for the primary outcome. Regression techniques will be used to examine the influence of prognostic factors on the primary and secondary outcomes.Ethics and disseminationThis study has been reviewed and approved by the Mater Human Research Ethics Committee (Reference: HREC EC00332) and will follow the principles of Good Clinical Practice. The study results will be disseminated at national and international conferences and published in peer-reviewed journals.Trial registration numberACTRN12616001009404; Pre-results.

Does Early Second-Trimester Sonography Predict Adverse Perinatal Outcomes in Monochorionic Diamniotic Twin Pregnancies?

2014 ◽  
Vol 33 (9) ◽  
pp. 1573-1578 ◽  
Author(s):  
M. Baraa Allaf ◽  
Winston A. Campbell ◽  
Anthony M. Vintzileos ◽  
Sina Haeri ◽  
Pouya Javadian ◽  
...  
Keyword(s):  
Perinatal Outcomes ◽  
Second Trimester ◽  
Adverse Perinatal Outcomes ◽  
Twin Pregnancies

Adenomyosis and adverse perinatal outcomes: increased risk of second trimester miscarriage, preeclampsia, and placental malposition

2017 ◽  
Vol 31 (3) ◽  
pp. 364-369 ◽  
Author(s):  
Ayako Hashimoto ◽  
Takayuki Iriyama ◽  
Seisuke Sayama ◽  
Toshio Nakayama ◽  
Atsushi Komatsu ◽  
...  
Keyword(s):  
Perinatal Outcomes ◽  
Second Trimester ◽  
Increased Risk ◽  
Adverse Perinatal Outcomes

scholarly journals Cerebroplacental Ratio to Predict Adverse Perinatal Outcomes in Small-for-Gestational-Age Pregnancies

Perinatology ◽  
2020 ◽  
Vol 31 (1) ◽  
pp. 14
Author(s):  
Jaeyoung Park ◽  
Minji Ko ◽  
Byung Soo Kang ◽  
Jihyun Park ◽  
Hyun Sun Ko ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Perinatal Outcomes ◽  
Cerebroplacental Ratio ◽  
Adverse Perinatal Outcomes

Prenatal ultrasonographic markers for prediction of complex gastroschisis and adverse perinatal outcomes: a systematic review and meta-analysis

2021 ◽  
pp. fetalneonatal-2021-322612
Author(s):  
Raphael C Sun ◽  
Kamran Hessami ◽  
Eyal Krispin ◽  
Mohan Pammi ◽  
Shayan Mostafaei ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Perinatal Outcomes ◽  
Length Of Hospital Stay ◽  
Abdominal Circumference ◽  
Second Trimester ◽  
Third Trimester ◽  
Not Otherwise Specified ◽  
Postnatal Mortality ◽  
Adverse Perinatal Outcomes ◽  
Full Enteral Feeding

ObjectiveWe sought to perform a meta-analysis of the predictive value of antenatal ultrasonographic markers of bowel dilation, gastric dilation, polyhydramnios and abdominal circumference that predict complex gastroschisis and adverse perinatal outcomesData sourcesPubMed, Web of Science, Scopus and Embase were searched for relevant articles up to December 2020. Studies reporting prenatal ultrasonographic markers including intra-abdominal bowel dilation (IABD), extra-abdominal bowel dilation (EABD), bowel wall thickness, polyhydramnios, abdominal circumference <5th percentile, gastric dilation (GD) and bowel dilation not otherwise specified (BD-NOS) were included. The primary outcome was prediction of complex gastroschisis; secondary outcomes were length of hospital stay for newborn, time to full enteral feeding, postnatal mortality rate, incidence of necrotising enterocolitis and short bowel syndrome.ResultsThirty-six studies were included in this meta-analysis. We found significant associations between complex gastroschisis and IABD (OR=5.42; 95% CI 3.24 to 9.06), EABD (OR=2.27; 95% CI 1.40 to 3.66), BD-NOS (OR=6.27; 95% CI 1.97 to 19.97), GD (OR=1.88; 95% CI 1.22 to 2.92) and polyhydramnios (OR=6.93; 95% CI 3.39 to 14.18). Second trimester IABD and EABD have greater specificity for the prediction of complex gastroschisis than third trimester values with specificity of 95.6% (95% CI 58.1 to 99.7) and 94.6% (95% CI 86.7 to 97.9) for the second trimester IABD and EABD, respectively.ConclusionPrenatal ultrasonographic markers, especially the second trimester IABD and EABD, can identify fetuses that develop complex gastroschisis. Furthermore, these specific ultrasonographic markers can identify those babies at the highest risk for severe complications of this congenital anomaly and hence selected for future antenatal interventions.

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