Novel ester derivative of cinnamates with different long alkoxy chain: synthesis, mesomorphic properties, biological evaluation

2021 ◽  
pp. 1-25
Author(s):  
Pradip C. Bhalodiya ◽  
Hemant N. Patel ◽  
Tejasvi H. Parmar ◽  
Chetan B. Sangani ◽  
Dhanji P. Rajani
Keyword(s):  
Biological Evaluation ◽  
Ester Derivative ◽  
Chain Synthesis ◽  
Mesomorphic Properties

scholarly journals Synthesis and Biological Evaluation of Substituted Thiophenyl Derivatives of Indane-1, 3-Dione

2007 ◽  
Vol 4 (3) ◽  
pp. 428-433 ◽  
Author(s):  
D. Giles ◽  
M. S. Prakash ◽  
K. V. Ramseshu
Keyword(s):  
Ethyl Acetate ◽  
Sulphuric Acid ◽  
Sodium Salt ◽  
Sodium Ethoxide ◽  
Biological Evaluation ◽  
Diethyl Phthalate ◽  
Anticancer Activities ◽  
Ester Derivative ◽  
Synthesis And Biological Evaluation ◽  
Derivatives Of

Indane-1, 3-dione (1) synthesized by condensation of diethyl phthalate and ethyl acetate in presence of sodium ethoxide gave sodium salt of ester derivative, which on neutralization in presence of sulphuric acid afford1. Various thiols where converted to their respective disulphide (3) which on treatment with1gave 2-substituted thio phenyl derivatives (4a-g) of1. The synthesized compounds were characterized on the basis of I.R and H1NMR. Synthesized compounds (4a-g) were investigated for their anticoagulant, analgesic, anti-inflammatory, antifungal, antibacterial and anticancer activities. Some of the synthesized compounds have shown moderate activities.

Chemical and biological evaluation of native bamboo species from atlantic rain forest

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
MT Grombone-Guaratini ◽  
LM Brandão Torres ◽  
DA Faria ◽  
CM José
Keyword(s):  
Rain Forest ◽  
Biological Evaluation ◽  
Atlantic Rain Forest ◽  
Bamboo Species

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF 3-FORMYL INDOLE BASED SCHIFF BASES

2018 ◽  
Vol 7 (6) ◽  
Author(s):  
Singh Gurvinder ◽  
Singh Prabhsimran ◽  
Dhawan R. K.
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Analysis ◽  
Schiff Bases ◽  
Antimicrobial Agents ◽  
Biological Evaluation ◽  
Fungal Strain ◽  
Bacterial Strains ◽  
Standard Drug ◽  
Gram Negative ◽  
E Coli

In order to develop new antimicrobial agents, a series of 3-formyl indole based Schiff bases were synthesized by reacting 3-formyl indole(indole-3-carboxaldehyde) with substituted aniline taking ethanol as solvent. The reaction was carried in the presence of small amount of p-toluene sulphonic acid as catalyst.All the synthesized compounds were characterized by IR, 1H-NMR spectral analysis. All the synthesized compounds were evaluated for antimicrobial activity against two gram positive bacterial strains (B. subtilisand S. aureus) and two gram negative bacterial strains (P. aeruginosaand E. coli) and one fungal strain (C. albicans). All the synthesized compounds were found to have moderate to good antimicrobial activity. The  standard drug amoxicillin, fluconazole were used for antimicrobial activity. Among the synthesized compounds, the maximum antimicrobial activity was shown by compounds GS04, GS07, GS08 and GS10.

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