Synthesis and Biological Activity Evaluation of Some Binuclear Metal Complexes of Cu(II) and Zn(II) with Tridentate Schiff Base Ligands

2012 ◽  
Vol 42 (2) ◽  
pp. 165-170 ◽  
Author(s):  
Akbar Mobinikhaledi ◽  
Mojgan Zendehdel ◽  
Parvin Safari ◽  
Ahmad Hamta ◽  
S. Mehdi Shariatzadeh
Keyword(s):  
Biological Activity ◽  
Schiff Base ◽  
Metal Complexes ◽  
Schiff Base Ligands ◽  
Activity Evaluation ◽  
Binuclear Metal ◽  
Tridentate Schiff Base

scholarly journals Spectroscopic and biological activity studies on tridentate Schiff base ligands and their transition metal complexes

2011 ◽  
Vol 2 (2) ◽  
pp. 178-188 ◽  
Author(s):  
Hanan Farouk Abd El-Halim ◽  
Mohamed Mohamed Omar ◽  
Gehad Genidy Mohamed ◽  
Mohsen Abou El-Ela Sayed
Keyword(s):  
Biological Activity ◽  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Schiff Base Ligands ◽  
Tridentate Schiff Base

scholarly journals Synthesis and Antimicrobial Studies of Tridentate Schiff Base Ligands with Pyrazolone Moiety and Their Metal Complexes

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Ramasamy Jayarajan ◽  
Gnanasambandam Vasuki ◽  
Pillutla Sambasiva Rao
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Schiff Base ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Schiff Base Ligands ◽  
E Coli ◽  
Antimicrobial Studies ◽  
Rhizopus Sp ◽  
Tridentate Schiff Base

Synthesis, characterization, and antimicrobial activity of tridentate Schiffbase ligands containing pyrazolone moiety (3a and 3b) and their transition metal complexes of VO(II), Cu(II), Fe(III), and Co(II) 4a–h have been investigated. The complexes show enhanced antibacterial activity against S. aureus, E. coli, and S. typhi and antifungal activity against C. albicans, Rhizopus sp., and A. niger compared to the ligands.

scholarly journals Characterization and antidiabetic activity of salicylhydrazone Schiff base vanadium(IV) and (V) complexes

2020 ◽  
Author(s):  
Janusz Szklarzewicz ◽  
Anna Jurowska ◽  
Maciej Hodorowicz ◽  
Grzegorz Kazek ◽  
Barbara Mordyl ◽  
...  
Keyword(s):  
Biological Activity ◽  
Schiff Base ◽  
Structure Determination ◽  
Antidiabetic Activity ◽  
Spectroscopic Methods ◽  
Schiff Base Ligands ◽  
X Ray ◽  
Dependent Activity ◽  
Hepg2 Cell Lines ◽  
Tridentate Schiff Base

AbstractTwenty-four oxidovanadium(IV,V) complexes with tridentate Schiff base ligands based on 5-nitrosalicylaldehyde, 5-methoxysalicylaldehyde, or 5-sulfosalicylaldehyde and respective hydrazide were isolated, and characterized using physicochemical and spectroscopic methods. Three of them were structurally characterized by single-crystal X-ray structure determination. The biological activity studies included inhibition of human tyrosine phosphatases, studies on myocyte C2C12, adipocyte 3T3-L1, and human hepatocyte HepG2 cell lines, glucose uptake in myocytes and adipocytes, and cytotoxicity tests. The complexes that were unstable in solutions showed biological activity typical of other V(IV) complexes, while the stable one showed much higher, ligand-dependent, activity.

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