BINDING CHARACTERISTICS OF A WATER-SOLUBLE β-CYCLODEXTRIN POLYMER

2000 ◽  
Vol 23 (3) ◽  
pp. 411-421 ◽  
Author(s):  
T. Cserháti ◽  
E. Forgács ◽  
Gy. Oros
Keyword(s):  
Water Soluble ◽  
Binding Characteristics ◽  
Cyclodextrin Polymer

Synthesis of a novel linear water-soluble ?-cyclodextrin polymer

2005 ◽  
Vol 54 (3) ◽  
pp. 594-599 ◽  
Author(s):  
Estelle Renard ◽  
Gis�le Volet ◽  
Catherine Amiel
Keyword(s):  
Water Soluble ◽  
Cyclodextrin Polymer

Investigation of water-soluble inclusion complex of hypericin with β-cyclodextrin polymer

2013 ◽  
Vol 95 (1) ◽  
pp. 366-370 ◽  
Author(s):  
Wang Zhang ◽  
Xiangdong Gong ◽  
Yin Cai ◽  
Chuanli Zhang ◽  
Xing Yu ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
Water Soluble ◽  
Cyclodextrin Polymer

Association of poly-N-[tris(hydroxymethyl)methyl] acrylamide with a water soluble β-cyclodextrin polymer

2002 ◽  
Vol 38 (4) ◽  
pp. 649-654 ◽  
Author(s):  
Noëlle Martine Gosselet ◽  
Horacio Naranjo ◽  
Estelle Renard ◽  
Catherine Amiel ◽  
Bernard Sebille
Keyword(s):  
Water Soluble ◽  
Cyclodextrin Polymer

Water-soluble inclusion complex of fullerene with γ-cyclodextrin polymer for photodynamic therapy

2014 ◽  
Vol 2 (31) ◽  
pp. 5107-5115 ◽  
Author(s):  
Wang Zhang ◽  
Xiangdong Gong ◽  
Chang Liu ◽  
Yuanzhe Piao ◽  
Yun Sun ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Inclusion Complex ◽  
Water Soluble ◽  
Cyclodextrin Polymer ◽  
Uva Irradiation

A method was developed to obtain a highly water-soluble C60–γ-CDP inclusion complex, which could efficiently generate 1O2 species with UVA irradiation.

scholarly journals Complexation of several drugs with water-soluble cyclodextrin polymer.

1987 ◽  
Vol 35 (1) ◽  
pp. 282-288 ◽  
Author(s):  
JULIANNA SZEMAN ◽  
HARUHISA UEDA ◽  
JOZSEF SZEJTLI ◽  
EVA FENYVESI ◽  
YOSHIHARU MACHIDA ◽  
...  
Keyword(s):  
Water Soluble ◽  
Cyclodextrin Polymer

Folate Receptor Saturation, Recycling, and Release Kinetics in Activated Macrophages

Blood ◽  
2008 ◽  
Vol 112 (11) ◽  
pp. 4655-4655
Author(s):  
Bindu Varghese ◽  
Erina Vlashi ◽  
Philip S. Low
Keyword(s):  
Folic Acid ◽  
Folate Receptor ◽  
Release Kinetics ◽  
Water Soluble ◽  
Imaging Agents ◽  
Activated Macrophages ◽  
Binding Characteristics ◽  
Folate Conjugate ◽  
Made In

Abstract Activated macrophages over-express a receptor for the vitamin, folic acid. Conjugation of folic acid to low molecular weight drugs, genes, liposomes, nanoparticles, and imaging agents does not significantly compromise the vitamin’s affinity for its receptor, thus facilitating both therapeutic and imaging agents to be targeted as folate conjugates to activated macrophages. In these studies the in vivo kinetics and binding characteristics of the folate receptor on macrophages has been characterized with the objective of optimizing targeted drug delivery. Our results show that saturation of the receptor in inflamed tissues can be reached at a dose of 100 nmol/kg. Furthermore, the rapid recycling characteristics of the receptor (every 10–20 minutes) suggests that frequent dosing will allow for maximal uptake of folate conjugates by activated macrophages accumulated in inflamed tissues. Finally, the short circulation half-life (30 minutes) of the water-soluble folate conjugate used in this study minimizes the possibility of nonspecific uptake by receptor-negative tissues. The kinetic observations made in this study can be utilized to optimize the therapeutic efficacy and imaging agent delivery of folate conjugates to activated macrophages in vivo.

One-step facile process to obtain insoluble polysaccharides fibrous mats from electrospinning of water-soluble PMDA/cyclodextrin polymer

2018 ◽  
Vol 135 (28) ◽  
pp. 46490 ◽  
Author(s):  
Claudio Cecone ◽  
Fabrizio Caldera ◽  
Anastasia Anceschi ◽  
Dominique Scalarone ◽  
Francesco Trotta ◽  
...  
Keyword(s):  
Water Soluble ◽  
Cyclodextrin Polymer ◽  
One Step ◽  
Insoluble Polysaccharides
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