scholarly journals Mechanisms Involved in the Low‐Level Regeneration of CD4+Cells in HIV‐1–Infected Patients Receiving Highly Active Antiretroviral Therapy Who Have Prolonged Undetectable Plasma Viral Loads

2005 ◽  
Vol 191 (10) ◽  
pp. 1670-1679 ◽  
Author(s):  
Olivier Benveniste ◽  
Antoine Flahault ◽  
Florence Rollot ◽  
Carole Elbim ◽  
Jérôme Estaquier ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Cd4 Cells ◽  
Low Level ◽  
Viral Loads ◽  
Highly Active ◽  
Undetectable Plasma ◽  
Hiv 1

scholarly journals Persistent low-level viraemia and virological failure in HIV-1-infected patients treated with highly active antiretroviral therapy

HIV Medicine ◽  
2006 ◽  
Vol 7 (7) ◽  
pp. 437-441 ◽  
Author(s):  
S Sungkanuparph ◽  
RK Groger ◽  
ET Overton ◽  
VJ Fraser ◽  
WG Powderly
Keyword(s):  
Antiretroviral Therapy ◽  
Virological Failure ◽  
Highly Active Antiretroviral Therapy ◽  
Low Level ◽  
Highly Active ◽  
Hiv 1

scholarly journals Genotypic Resistance in HIV‐1–Infected Patients with Persistently Detectable Low‐Level Viremia while Receiving Highly Active Antiretroviral Therapy

2004 ◽  
Vol 39 (7) ◽  
pp. 1030-1037 ◽  
Author(s):  
Richard E. Nettles ◽  
Tara L. Kieffer ◽  
Rachel P. Simmons ◽  
Joseph Cofrancesco, Jr. ◽  
Richard D. Moore ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Genotypic Resistance ◽  
Low Level ◽  
Highly Active ◽  
Hiv 1

scholarly journals Quantification of HIV-1 proviral DNA in patients with undetectable plasma viremia over long-term highly active antiretroviral therapy

2000 ◽  
Vol 4 (4) ◽  
pp. 187-193 ◽  
Author(s):  
Maurizia Debiaggi ◽  
Francesca Zara ◽  
Angela Pistorio ◽  
Raffaele Bruno ◽  
Paolo Sacchi ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Plasma Viremia ◽  
Proviral Dna ◽  
Highly Active ◽  
Undetectable Plasma ◽  
Hiv 1

Profile of Patients With Kaposi's Sarcoma in the Era of Highly Active Antiretroviral Therapy

2005 ◽  
Vol 23 (6) ◽  
pp. 1253-1260 ◽  
Author(s):  
James H. Gallafent ◽  
Susan E. Buskin ◽  
Peter B. De Turk ◽  
David M. Aboulafia
Keyword(s):  
Antiretroviral Therapy ◽  
Drug Use ◽  
Highly Active Antiretroviral Therapy ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Alcohol Problems ◽  
King County ◽  
Viral Loads ◽  
Highly Active ◽  
Hiv 1

Purpose Since the advent of highly active antiretroviral therapy (HAART), the incidence of Kaposi's sarcoma (KS) among AIDS patients has declined both nationwide and in King County, Washington. We sought to compare clinical parameters of patients diagnosed with KS in the pre-HAART (1990 to 1996) and HAART (1997 to 2002) eras. Methods We used patient data abstracted from the Adult/Adolescent Spectrum of HIV-Related Diseases study of Public Health—Seattle and King County. Results Patients diagnosed with KS in the HAART era (n = 40) were significantly more likely (P < .05) than pre–HAART-era KS patients (n = 366) to be diagnosed with alcohol problems (43% v 18%), noninjection drug use (45% v 18%), injection drug use (25% v 10%), psychosis (25% v 13%), and hypertension (13% v 2%). Although median CD4+ count and HIV-1 viral load at the time of KS diagnosis were not significantly different between the two groups, significantly fewer (P < .01) HAART-era KS patients developed opportunistic illnesses (OIs) during their follow-up. The risk of dying among KS patients diagnosed in the HAART era is significantly lower (P < .01) than for KS patients diagnosed in the pre-HAART era (hazard ratio, 0.24). Conclusion Although HAART-era KS patients in King County were as likely to have a depleted CD4+ cell count and high HIV-1 viral loads at the time of KS diagnosis as pre-HAART KS patients, they survived longer and fewer of them were diagnosed with other OIs. They also had an increased prevalence of substance abuse and mental illness, contributing to a dynamic and changing KS clinical profile.

scholarly journals Low‐Level Viremia and Proviral DNA Impede Immune Reconstitution in HIV‐1–Infected Patients Receiving Highly Active Antiretroviral Therapy

2005 ◽  
Vol 191 (3) ◽  
pp. 348-357 ◽  
Author(s):  
Sisse R. Ostrowski ◽  
Terese L. Katzenstein ◽  
Per T. Thim ◽  
Bente K. Pedersen ◽  
Jan Gerstoft ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Immune Reconstitution ◽  
Low Level ◽  
Proviral Dna ◽  
Highly Active ◽  
Hiv 1

scholarly journals High frequency of genotypic resistance in HIV-1-infected patients on highly active antiretroviral therapy with persistent low level viremia

2012 ◽  
Vol 15 (6(Suppl 4)) ◽  
Author(s):  
D Pellegrino ◽  
L Brígido ◽  
J Souza Cavalcanti ◽  
J Paula Ferreira ◽  
J Vidal ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
High Frequency ◽  
Genotypic Resistance ◽  
Low Level ◽  
Highly Active ◽  
Hiv 1

Cell-associated HIV-1-DNA quantitation after highly active antiretroviral therapy-treated primary infection in patients with persistently undetectable plasma HIV-1 RNA

AIDS ◽  
2000 ◽  
Vol 14 (18) ◽  
pp. 2851-2855 ◽  
Author(s):  
Isabelle Garrigue ◽  
Isabelle Pellegrin ◽  
Bruno Hoen ◽  
Béatrice Dumon ◽  
Martine Harzic ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Primary Infection ◽  
Highly Active ◽  
Dna Quantitation ◽  
Undetectable Plasma ◽  
Hiv 1

Simplification with abacavir-based triple nucleoside therapy versus continued protease inhibitor-based highly active antiretroviral therapy in HIV-1-infected patients with undetectable plasma HIV-1 RNA

AIDS ◽  
2001 ◽  
Vol 15 (12) ◽  
pp. 1517-1526 ◽  
Author(s):  
Nathan Clumeck ◽  
Frank Goebel ◽  
Willy Rozenbaum ◽  
Jan Gerstoft ◽  
Schlomo Staszewski ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Protease Inhibitor ◽  
Highly Active Antiretroviral Therapy ◽  
Highly Active ◽  
Undetectable Plasma ◽  
Hiv 1

scholarly journals A Comparison of Viral Loads between HIV‐1–Infected Elite Suppressors and Individuals Who Receive Suppressive Highly Active Antiretroviral Therapy

2008 ◽  
Vol 47 (1) ◽  
pp. 102-104 ◽  
Author(s):  
Jason B. Dinoso ◽  
Scott Y. Kim ◽  
Robert F. Siliciano ◽  
Joel N. Blankson
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Viral Loads ◽  
Highly Active ◽  
Elite Suppressors ◽  
Hiv 1
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