scholarly journals Application of fluence field modulation to proton computed tomography for proton therapy imaging

2017 ◽  
Vol 62 (15) ◽  
pp. 6026-6043 ◽  
Author(s):  
G Dedes ◽  
L De Angelis ◽  
S Rit ◽  
D Hansen ◽  
C Belka ◽  
...  
Author(s):  
Valeria Sipala ◽  
Mara Bruzzi ◽  
Mirko Brianzi ◽  
Marta Bucciolini ◽  
Giuseppe Antonio Pablo Cirrone ◽  
...  

2011 ◽  
Vol 26 (10n11) ◽  
pp. 1761-1774 ◽  
Author(s):  
BELA ERDELYI

Novel accelerator technology, including Fixed Field Alternating Gradient Accelerators (FFAG) coupled with medical imaging devices, hold significant promise for enhanced proton therapy. The accuracy and efficiency of proton therapy treatments will see improvements with the implementation of proton computed tomography (pCT), currently under development. Here, we analyze the robustness of the image reconstruction method in pCT with respect to three different error sources and conclude that pCT is inherently resilient with respect to errors in mean ionization potential, discrete sampling of proton trajectories and bias in the limit of large radiation doses.


2009 ◽  
Author(s):  
Vladimir Bashkirov ◽  
Reinhard Schulte ◽  
George Coutrakon ◽  
Bela Erdelyi ◽  
Kent Wong ◽  
...  

2005 ◽  
Vol 34 (6) ◽  
pp. 481-492 ◽  
Author(s):  
Joaquim Teixeira de Assis ◽  
Olga Yevseyeva, ◽  
Ivan Evseev ◽  
Ricardo Tadeu Lopes ◽  
Hugo Reuters Schelin ◽  
...  

2021 ◽  
Vol 60 (5) ◽  
pp. 598-604
Author(s):  
Kia Busch ◽  
Benjamin Dahl ◽  
Stine E. Petersen ◽  
Heidi S. Rønde ◽  
Lise Bentzen ◽  
...  

Author(s):  
Marc Granado-González ◽  
César Jesús-Valls ◽  
Thorsten Lux ◽  
Tony Price ◽  
Federico Sánchez

Abstract Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been asharp uptake of proton beam therapy in recent years as improved delivery techniques and patient benefits are observed. However, treatments are currently planned using conventional x-ray CT images due to the absence of devices able to perform high quality proton computed tomography(pCT) under realistic clinical conditions. A new plastic-scintillator-based range telescope concept, named ASTRA, is proposed here to measure the proton’s energy loss in a pCT system. Simulations conducted using GEANT4 yield an expected energy resolution of 0.7%. If calorimetric information is used the energy resolution could be further improved to about 0.5%. In addition, the ability of ASTRA to track multiple protons simultaneously is presented. Due to its fast components, ASTRA is expected to reach unprecedented data collection rates, similar to 10^8 protons/s.The performance of ASTRA has also been tested by simulating the imaging of phantoms. The results show excellent image contrast and relative stopping power reconstruction.


2015 ◽  
Vol 2 (2) ◽  
pp. 404-414 ◽  
Author(s):  
Catarina Veiga ◽  
Jailan Alshaikhi ◽  
Richard Amos ◽  
Ana Mónica Lourenço ◽  
Marc Modat ◽  
...  

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