A novel range telescope concept for proton CT

Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been asharp uptake of proton beam therapy in recent years as improved delivery techniques and patient benefits are observed. However, treatments are currently planned using conventional x-ray CT images due to the absence of devices able to perform high quality proton computed tomography(pCT) under realistic clinical conditions. A new plastic-scintillator-based range telescope concept, named ASTRA, is proposed here to measure the proton’s energy loss in a pCT system. Simulations conducted using GEANT4 yield an expected energy resolution of 0.7%. If calorimetric information is used the energy resolution could be further improved to about 0.5%. In addition, the ability of ASTRA to track multiple protons simultaneously is presented. Due to its fast components, ASTRA is expected to reach unprecedented data collection rates, similar to 10^8 protons/s.The performance of ASTRA has also been tested by simulating the imaging of phantoms. The results show excellent image contrast and relative stopping power reconstruction.

Different radiographic imaging modalities with a proton computed tomography demonstrator

Proton computed tomography aims at improving proton-beam therapy, which is an established method to treat deep-seated tumours in cancer therapy. In treatment planning, the stopping power (SP) within a patient, describing the energy loss of a proton in a tissue, has to be known with high accuracy. However, conventional computed tomography (CT) returns Hounsfield units (HU), which have to be converted to SP values to perform the required treatment planning, thus introducing range uncertainties in the calculated dose distribution. Using protons not only for therapy but also for the preceding planning CT enables the direct measurement of the SP. Hence, this imaging modality eliminates the need for further conversion and therefore offers the possibility to improve treatment planning in proton therapy. In order to examine the principles of such a proton CT (pCT) setup, a demonstrator system, consisting of four double-sided silicon strip detectors and a range telescope, was built. The performance of the pCT demonstrator was tested with measurements at the MedAustron facility in Wiener Neustadt, Austria. In this paper, 2D imaging modalities going beyond the idea of a standard proton radiography, will be discussed. Namely, fluence loss imaging and scattering radiography results obtained with the demonstrator will be shown. The advantage of these modalities is that they do not rely on an additional energy measurement and can therefore be conducted only with the tracker of the demonstrator.

A prototype of pCT scanner: first tests

Proton therapy technique for cancer treatment offers a high selectivity with respect to conventional radiotherapy with X- and γ-rays due to the properties of the interaction of protons with matter. Very accurate and precise treatment plans and a good control on the dose deposition are required to exploit the full potential of the technique. The substitution of the currently used X-ray Computed Tomography (xCT) by proton Computed Tomography (pCT) in the design of treatment plans would allow for a reduction in proton range uncertainties. This would make possible an important improvement in the accuracy and precision of treatment plans. With this aim, a prototype of pCT scanner is under study. It includes two tracking detectors which provide information on the proton trajectories and a residual energy detector to determine the energy loss while traversing the object scanned. A proof-of-concept experiment has been performed using low-energy protons and a simplified prototype with only the two tracking detectors. The results obtained in the measurement are presented and discussed.