scholarly journals Experimental realization of dynamic fluence field optimization for proton computed tomography

2020 ◽  
Vol 65 (19) ◽  
pp. 195001 ◽  
Author(s):  
J Dickmann ◽  
C Sarosiek ◽  
V Rykalin ◽  
M Pankuch ◽  
S Rit ◽  
...  
Author(s):  
Marc Granado-González ◽  
César Jesús-Valls ◽  
Thorsten Lux ◽  
Tony Price ◽  
Federico Sánchez

Abstract Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been asharp uptake of proton beam therapy in recent years as improved delivery techniques and patient benefits are observed. However, treatments are currently planned using conventional x-ray CT images due to the absence of devices able to perform high quality proton computed tomography(pCT) under realistic clinical conditions. A new plastic-scintillator-based range telescope concept, named ASTRA, is proposed here to measure the proton’s energy loss in a pCT system. Simulations conducted using GEANT4 yield an expected energy resolution of 0.7%. If calorimetric information is used the energy resolution could be further improved to about 0.5%. In addition, the ability of ASTRA to track multiple protons simultaneously is presented. Due to its fast components, ASTRA is expected to reach unprecedented data collection rates, similar to 10^8 protons/s.The performance of ASTRA has also been tested by simulating the imaging of phantoms. The results show excellent image contrast and relative stopping power reconstruction.


2017 ◽  
Vol 62 (15) ◽  
pp. 6026-6043 ◽  
Author(s):  
G Dedes ◽  
L De Angelis ◽  
S Rit ◽  
D Hansen ◽  
C Belka ◽  
...  

2019 ◽  
Vol 64 (14) ◽  
pp. 145016 ◽  
Author(s):  
J Dickmann ◽  
P Wesp ◽  
M Rädler ◽  
S Rit ◽  
M Pankuch ◽  
...  

Author(s):  
Jun Zhou ◽  
Xiaoqiang Li ◽  
Peyman Kabolizadeh ◽  
Di Yan ◽  
Craig Stevens ◽  
...  

2018 ◽  
Vol 55 ◽  
pp. 149-154 ◽  
Author(s):  
Michela Esposito ◽  
Chris Waltham ◽  
Jonathan T. Taylor ◽  
Sam Manger ◽  
Ben Phoenix ◽  
...  

2008 ◽  
pp. 3-16
Author(s):  
Jerome Zhengrong Liang ◽  
Tianfang Li ◽  
Reinhard W. Schulte ◽  
Todd J. Satogata ◽  
David C. Williams ◽  
...  

2013 ◽  
Vol 8 (02) ◽  
pp. C02021-C02021 ◽  
Author(s):  
V Sipala ◽  
M Bruzzi ◽  
M Bucciolini ◽  
M Carpinelli ◽  
G A P Cirrone ◽  
...  

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