Multi-segment spectral reconstruction via zero-value set prior

2021 ◽  
Author(s):  
Yizhong Wang ◽  
Wenkun Zhang ◽  
Ailong Cai ◽  
Ningning Liang ◽  
Zhe Wang ◽  
...  
Keyword(s):  
Value Set ◽  
Spectral Reconstruction

HIGH-RESOLUTION SPECTRAL RECONSTRUCTION: METHOD AND APPLICATIONS FOR CONTAMINATION MEASUREMENT, DIGITAL SAMPLING, AND CONTINUITY ASSESSMENT

2020 ◽  
Author(s):  
Christopher Michael Jones ◽  
◽  
Yngve B Johansen ◽  
Artur Kotwicki ◽  
Cameron Rekully ◽  
...  
Keyword(s):  
High Resolution ◽  
Reconstruction Method ◽  
Digital Sampling ◽  
Spectral Reconstruction

scholarly journals EQ-5D-Y Value Set for Slovenia

2021 ◽  
Author(s):  
Valentina Prevolnik Rupel ◽  
◽  
Marko Ogorevc
Keyword(s):  
Value Set

United States Utility Algorithm for the EORTC QLU-C10D, a Multiattribute Utility Instrument Based on a Cancer-Specific Quality-of-Life Instrument

2021 ◽  
pp. 0272989X2110035
Author(s):  
Dennis A. Revicki ◽  
Madeleine T. King ◽  
Rosalie Viney ◽  
A. Simon Pickard ◽  
Rebecca Mercieca-Bebber ◽  
...  
Keyword(s):  
Quality Of Life ◽  
United States ◽  
Emotional Functioning ◽  
Health State ◽  
Life Questionnaire ◽  
Multiattribute Utility ◽  
Value Set ◽  
Eortc Qlq C30 ◽  
Eortc Qlq

Background The EORTC QLU-C10D is a multiattribute utility measure derived from the cancer-specific quality-of-life questionnaire, the EORTC QLQ-C30. The QLU-C10D contains 10 dimensions (physical, role, social and emotional functioning, pain, fatigue, sleep, appetite, nausea, bowel problems). The objective of this study was to develop a United States value set for the QLU-C10D. Methods A US online panel was quota recruited to achieve a representative sample for sex, age (≥18 y), race, and ethnicity. Respondents undertook a discrete choice experiment, each completing 16 choice-pairs, randomly assigned from a total of 960 choice-pairs. Each pair included 2 QLU-C10D health states and duration. Data were analyzed using conditional logistic regression, parameterized to fit the quality-adjusted life-year framework. Utility weights were calculated as the ratio of each dimension-level coefficient to the coefficient for life expectancy. Results A total of 2480 panel members opted in, 2333 (94%) completed at least 1 choice-pair, and 2273 (92%) completed all choice-pairs. Within dimensions, weights were generally monotonic. Physical functioning, role functioning, and pain were associated with the largest utility weights. Cancer-specific dimensions, such as nausea and bowel problems, were associated with moderate utility decrements, as were general issues such as problems with emotional functioning and social functioning. Sleep problems and fatigue were associated with smaller utility decrements. The value of the worst health state was 0.032, which was slightly greater than 0 (equivalent to being dead). Conclusions This study provides the US-specific value set for the QLU-C10D. These estimated health state scores, based on responses to the EORTC QLQ-C30 questionnaire, can be used to evaluate the cost-utility of oncology treatments.

scholarly journals Robust Stabilization of Interval Plants with Uncertain Time-Delay Using the Value Set Concept

Mathematics ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 429
Author(s):  
Pedro Zamora ◽  
Alejandro Arceo ◽  
Noé Martínez ◽  
Gerardo Romero ◽  
Luis E. Garza
Keyword(s):  
Time Delay ◽  
Robust Stabilization ◽  
Parametric Uncertainty ◽  
Exclusion Principle ◽  
Control Synthesis ◽  
Classical Orthogonal Polynomials ◽  
Loop Control ◽  
Value Set ◽  
Interval Plants ◽  
Uncertain Time

This paper considers the robust stabilization problem for interval plants with parametric uncertainty and uncertain time-delay based on the value set characterization of closed-loop control systems and the zero exclusion principle. Using Kharitonov’s polynomials, it is possible to establish a sufficient condition to guarantee the robust stability property. This condition allows us to solve the control synthesis problem using conditions similar to those established in the loopshaping technique and to parameterize the controllers using stable polynomials constructed from classical orthogonal polynomials.

scholarly journals Estimating an EQ-5D-3L Value Set for Romania Using Time Trade-Off

2021 ◽  
Vol 18 (14) ◽  
pp. 7415
Author(s):  
Marian Sorin Paveliu ◽  
Elena Olariu ◽  
Raluca Caplescu ◽  
Yemi Oluboyede ◽  
Ileana-Gabriela Niculescu-Aron ◽  
...  
Keyword(s):  
Health Technology Assessment ◽  
Technology Assessment ◽  
Health Technology ◽  
Assessment Process ◽  
Computer Assisted ◽  
Health State ◽  
Health States ◽  
Value Set ◽  
Health Technologies ◽  
Related Quality

Objective: To provide health-related quality of life (HRQoL) data to support health technology assessment (HTA) and reimbursement decisions in Romania, by developing a country-specific value set for the EQ-5D-3L questionnaire. Methods: We used the cTTO method to elicit health state values using a computer-assisted personal interviewing approach. Interviews were standardized following the most recent version of the EQ-VT protocol developed by the EuroQoL Foundation. Thirty EQ-5D-3L health states were randomly assigned to respondents in blocks of three. Econometric modeling was used to estimate values for all 243 states described by the EQ-5D-3L. Results: Data from 1556 non-institutionalized adults aged 18 years and older, selected from a national representative sample, were used to build the value set. All tested models were logically consistent; the final model chosen to generate the value set was an interval regression model. The predicted EQ-5D-3L values ranged from 0.969 to 0.399, and the relative importance of EQ-5D-3L dimensions was in the following order: mobility, pain/discomfort, self-care, anxiety/depression, and usual activities. Conclusions: These results can support reimbursement decisions and allow regional cross-country comparisons between health technologies. This study lays a stepping stone in the development of a health technology assessment process more driven by locally relevant data in Romania.

scholarly journals Valuation of the EQ-5D-3L in Russia

2021 ◽  
Author(s):  
Vitaly Omelyanovskiy ◽  
Nuriya Musina ◽  
Svetlana Ratushnyak ◽  
Tatiana Bezdenezhnykh ◽  
Vlada Fediaeva ◽  
...  
Keyword(s):  
Health Problems ◽  
Cost Utility ◽  
Economic Evaluations ◽  
Computer Assisted ◽  
Health State ◽  
Primary Analysis ◽  
Health States ◽  
Value Set ◽  
Model Combining ◽  
Life Years

Abstract Purpose The most widely used generic questionnaire to estimate the quality of life for yielding quality-adjusted life years in economic evaluations is EQ-5D. Country-specific population value sets are required to use EQ-5D in economic evaluations. The aim of this study was to establish an EQ-5D-3L value set for Russia. Methods A representative sample aged 18+ years was recruited from the Russia`s general population. Computer-assisted face–to–face interviews were conducted based on the standardized valuation protocol using EQ-Portable Valuation Technology. Population preferences were elicited utilizing both composite time trade-off (cTTO) and discrete choice experiment (DCE) techniques. To estimate the value set, a hybrid regression model combining cTTO and DCE data was used. Results A total of 300 respondents who successfully completed the interview were included in the primary analysis. 120 (40.0%) respondents reported no health problems of any dimension, and 56 (18.7%) reported moderate health problems in one dimension of the EQ‐5D‐3L. Median self-rated health using EQ‐VAS was 80 with IQR 70–90. Comparing cTTO and DCE-predicted values for 243 health states resulted in a similar pattern. This supports the use of hybrid models. The predicted value based on the preferred model for the worst health state “33333” was −0.503. Mobility dimension had the most significant impact on the utility decrement, and anxiety/depression had the lowest decrement. Conclusion Determining a Russian national value set may be considered the first step towards promoting cost-utility analysis use to increase comparability among studies and improve the transferability of healthcare decision-making in Russia.

scholarly journals Design-Assisted of Pitching Aerofoils through Enhanced Identification of Coherent Flow Structures

Designs ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 11 ◽  
Author(s):  
Filippo Avanzi ◽  
Francesco De Vanna ◽  
Yin Ruan ◽  
Ernesto Benini
Keyword(s):  
Pressure Field ◽  
Navier Stokes ◽  
Flow Structures ◽  
Coupled Modes ◽  
Spectral Reconstruction ◽  
Sst Turbulence Model ◽  
Coherent Flow Structures ◽  
Highly Correlated ◽  
Naca 0012 ◽  
Proper Orthogonal

This study discusses a general framework to identify the unsteady features of a flow past an oscillating aerofoil in deep dynamic stall conditions. In particular, the work aims at demonstrating the advantages for the design process of the Spectral Proper Orthogonal Decomposition in accurately producing reliable reduced models of CFD systems and comparing this technique with standard snapshot-based models. Reynolds-Averaged Navier-Stokes system of equations, coupled with k−ω SST turbulence model, is used to produce the dataset, the latter consisting of a two-dimensional NACA 0012 aerofoil in the pitching motion. Modal analysis is performed on both velocity and pressure fields showing that, for vectored values, a proper tuning of the filtering process allows for better results compared to snapshot formulations and extract highly correlated coherent flow structures otherwise undetected. Wider filters, in particular, produce enhanced coherence without affecting the typical frequency response of the coupled modes. Conversely, the pressure field decomposition is drastically affected by the windowing properties. In conclusion, the low-order spectral reconstruction of the pressure field allows for an excellent prediction of aerodynamic loads. Moreover, the analysis shows that snapshot-based models better perform on the CFD values during the pitching cycle, while spectral-based methods better fit the loads’ fluctuations.

scholarly journals Valuing health-related quality of life among the Indian population: a protocol for the Development of an EQ-5D Value set for India using an Extended design (DEVINE) Study

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e039517
Author(s):  
Gaurav Jyani ◽  
Shankar Prinja ◽  
Sitanshu Sekhar Kar ◽  
Mayur Trivedi ◽  
Binod Patro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Added Value ◽  
Computer Assisted ◽  
Health Related Quality ◽  
Health States ◽  
Value Set ◽  
Related Quality ◽  
Health Related ◽  
The Government

IntroductionQuality-adjusted life year (QALY) has been recommended by the government as preferred outcome measure for Health Technology Assessment (HTA) in India. As country-specific health-related quality of life tariff values are essential for accurate measurement of QALYs, the government of India has commissioned the present study. The aim of this paper is to describe the methods for the Development of an EQ-5D Value set for India using an Extended design (DEVINE) Study. Additionally, this study aspires to establish if the design of 10-time trade-off (TTO) blocks is enough to generate valid value sets.Methods and analysisA cross-sectional survey using the EuroQol Group’s Valuation Technology (EQ-VT) will be undertaken in a sample of 2700 respondents selected from six different states of India using a multistage stratified random sampling technique. The participants will be interviewed using computer-assisted personal interviewing technique. The TTO valuation will be done using 10 composite TTO (c-TTO) tasks and 7 discrete choice experiment (DCE) tasks. Hybrid modelling approach using both c-TTO and DCE data to estimate the potential value set will be applied. Values of all 3125 health states will be predicted using both the conventional EQ-VT design of 10 blocks of 10 TTO tasks, and an extended design of 18 blocks of 10 TTO tasks. The potential added value of the eight additional blocks in overall validity will be tested. The study will deliver value set for India and assess the adequacy of existing 10-blocks design to be able to correctly predict the values of all 3125 health states.Ethics and disseminationThe ethical approval has been obtained from Institutional Ethics Committee of PGIMER, Chandigarh, India. The anonymised EQ-5D-5L value set will be available for general use and in the HTAs commissioned by India’s central HTA Agency.

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