scholarly journals 4D dosimetry and motion management in clinical radiotherapy

2019 ◽  
Vol 1305 ◽  
pp. 012049
Author(s):  
S Å J Bäck ◽  
R D Franich ◽  
A Edvardsson ◽  
S Ceberg
Author(s):  
M J Keikhai Farzaneh ◽  
M Momennezhad ◽  
Sh Naseri

One of the most important challenges in treatment of patients with cancerous tumors of chest and abdominal areas is organ movement. The delivery of treatment radiation doses to tumor tissue is a challenging matter while protecting healthy and radio sensitive tissues. Since the movement of organs due to respiration causes a discrepancy in the middle of planned and delivered dose distributions. The moderation in the fatalistic effect of intra-fractional target travel on the radiation therapy correctness is necessary for cutting-edge methods of motion remote monitoring and cancerous growth irradiancy. Tracking respiratory milling and implementation of breath-hold techniques by respiratory gating systems have been used for compensation of respiratory motion negative effects. Therefore, these systems help us to deliver precise treatments and also protect healthy and critical organs. It seems aspiration should be kept under observation all over treatment period employing tracking seed markers (e.g. fiducials), skin surface scanners (e.g. camera and laser monitoring systems) and aspiration detectors (e.g. spirometers). However, these systems are not readily available for most radiotherapy centers around the word. It is believed that providing and expanding the required equipment, gated radiotherapy will be a routine technique for treatment of chest and abdominal tumors in all clinical radiotherapy centers in the world by considering benefits of respiratory gating techniques in increasing efficiency of patient treatment in the near future.This review explains the different technologies and systems as well as some strategies available for motion management in radiotherapy centers.


2021 ◽  
Author(s):  
Ligong Lu ◽  
Yinchu Ma ◽  
Xin-Feng Tang ◽  
Youcui Xu ◽  
Wei Jiang ◽  
...  

The combination of chemotherapy and radiotherapy (chemoradiotherapy) is a promising strategy with extensively studied and applied clinically. Meanwhile, radiosensitizers play an important role in improving clinical radiotherapy therapeutic efficacy. There...


2008 ◽  
Vol 33 (4) ◽  
pp. 268-274 ◽  
Author(s):  
Joshua D. Lawson ◽  
Tim Fox ◽  
Eric Elder ◽  
Adam Nowlan ◽  
Lawrence Davis ◽  
...  

2018 ◽  
Vol 127 ◽  
pp. S221
Author(s):  
A. Derksen ◽  
L. König ◽  
N. Papenberg ◽  
T. Gass ◽  
B. Haas ◽  
...  

Author(s):  
William Ferris ◽  
Larry Albert DeWerd ◽  
Wesley S Culberson

Abstract Objective: Synchrony® is a motion management system on the Radixact® that uses planar kV radiographs to locate the target during treatment. The purpose of this work is to quantify the visibility of fiducials on these radiographs. Approach: A custom acrylic slab was machined to hold 8 gold fiducials of various lengths, diameters, and orientations with respect to imaging axis. The slab was placed on the couch at the imaging isocenter and planar radiographs were acquired perpendicular to the custom slab with varying thicknesses of acrylic on each side. Fiducial signal to noise ratio (SNR) and detected fiducial position error in millimeters were quantified. Main Results: The minimum output protocol (100 kVp, 0.8 mAs) was sufficient to detect all fiducials on both Radixact configurations when the thickness of the phantom was 20 cm. However, no fiducials for any protocol were detected when the phantom was 50 cm thick. The algorithm accurately detected fiducials on the image when the SNR was larger than 4. The MV beam was observed to cause RFI artifacts on the kV images and to decrease SNR by an average of 10%. Significance: This work provides the first data on fiducial visibility on kV radiographs from Radixact Synchrony treatments. The Synchrony fiducial detection algorithm was determined to be very accurate when sufficient SNR is achieved. However, a higher output protocol may need to be added for use with larger patients. This work provided groundwork for investigating visibility of fiducial-free solid targets in future studies and provided a direct comparison of fiducial visibility on the two Radixact configurations, which will allow for intercomparison of results between configurations.


1995 ◽  
Vol 34 (8) ◽  
pp. 995-1003 ◽  
Author(s):  
Lars R. Holsti

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