scholarly journals Analysis and regulation of the cardiovascular system of univentricular heart with different configurations of the total cavopulmonary connection

2021 ◽  
Vol 2091 (1) ◽  
pp. 012023
Author(s):  
A A Galiastov ◽  
D V Telyshev

Abstract The cardiovascular system (CVS) is a complex mechanism capable of reacting and regulating various changes in external and internal parameters. A particular problem is the study of CVS with univentricular heart. We studied the hemodynamic response of the CVS to the use of various configurations of bypassing the right side of the heart. During our research, we selected three different configurations of the total cavopulmonary connection. All configurations were made from Clear Flex 50 and tested in an experimental workbench. According to the research results, the TCPC-3 configuration is the most optimal. It has symmetrical output values of flows and pressures and there is no significant increase in inlet pressure. The results of this study can be used to optimize the control of the parameters of the ventricular assist device and the total artificial heart.

2014 ◽  
Vol 146 (5) ◽  
pp. S-322
Author(s):  
Jatinder Lachar ◽  
Sanah Christopher ◽  
Maureen Flattery ◽  
Keyur Shah ◽  
Daniel G. Tang ◽  
...  

Author(s):  
Teng Jing ◽  
Kun-Xi Qian

The main obstacle of artificial heart in extending its applications in clinic has been its over high price rather than technical property. The new generation of artificial heart must enable the patients to be able to afford it. The author's permanent maglev pumps, both VAD (ventricular assist device) and TAH (total artificial heart), reduce their price to lower than 10 USDs, ca.1/10 of the third generation of artificial heart electric maglev pump. Moreover, the permanent maglev pump not only retains all the advantages of the electric maglev pump, but also has many innovations: its impeller vane was designed according to the streamlines in the pump, so that the blood damage was reduced as low as possible; It can produce either nonpulsatile or pulsatile flow; It can be made in LVAD or TAH, as wish. Besides, it needs no rotor position detector, no electric magnetic push and pull device for rotor suspension, and no feed-back controller for levitation. This is why its costs can remarkably reduced. Animal experiments for up to two months and clinical trial lasted 43 hours of permanent maglev LVAD demonstrated that the performances were excellent and perfect.


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