Development of electron-tracking Compton imaging system with 30-μm SOI pixel sensor

2017 ◽  
Vol 12 (01) ◽  
pp. C01045-C01045 ◽  
Author(s):  
Y. Yoshihara ◽  
K. Shimazoe ◽  
Y. Mizumachi ◽  
H. Takahashi ◽  
K. Kamada ◽  
...  
Author(s):  
Yuri Yoshihara ◽  
Naoki Nakada ◽  
Yuki Mizumachi ◽  
Mizuki Uenomachi ◽  
Kenji Shimazoe ◽  
...  

2017 ◽  
Vol 12 (01) ◽  
pp. E01002-E01002
Author(s):  
Y. Yoshihara ◽  
K. Shimazoe ◽  
Y. Mizumachi ◽  
H. Takahashi ◽  
K. Kamada ◽  
...  

2016 ◽  
Vol 53 (12) ◽  
pp. 2040-2048 ◽  
Author(s):  
Young-su Kim ◽  
Jae Hyeon Kim ◽  
Hyun Su Lee ◽  
Han Rim Lee ◽  
Jong Hoon Park ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Makoto Sakai ◽  
Yoshiki Kubota ◽  
Raj Kumar Parajuli ◽  
Mikiko Kikuchi ◽  
Kazuo Arakawa ◽  
...  

Abstract We have been developing a medical imaging system using a Compton camera and demonstrated the imaging ability of Compton camera for 99mTc-DMSA accumulated in rat kidneys. In this study, we performed imaging experiments using a human body phantom to confirm its applicability to human imaging. Preliminary simulations were conducted using a digital phantom with varying activity ratios between the kidney and body trunk regions. Gamma rays (141 keV) were generated and detected by a Compton camera based on a silicon and cadmium telluride (Si/CdTe) detector. Compton images were reconstructed with the list mode median root prior expectation maximization method. The appropriate number of iterations of the condition was confirmed through simulations. The reconstructed Compton images revealed two bright points in the kidney regions. Furthermore, the numerical value calculated by integrating pixel values inside the region of interest correlated well with the activity of the kidney regions. Finally, experimental studies were conducted to ascertain whether the results of the simulation studies could be reproduced. The kidneys could be successfully visualised. In conclusion, considering that the conditions in this study agree with those of typical human bodies and imaginable experimental setup, the Si/CdTe Compton camera has a high probability of success in human imaging. In addition, our results indicate the capability of (semi-) quantitative analysis using Compton images.


2022 ◽  
Vol 17 (01) ◽  
pp. C01045
Author(s):  
Z. Zhihong ◽  
K. Shimazoe ◽  
H. Takahashi

Abstract Double-photon emission computed tomography (DPECT) has been proposed to overcome the disadvantage of a low signal-to-background ratio for conventional Compton imaging. This method has shown significant image reconstruction capability in the 2D plane. However, its performance is unsatisfactory when the field of view is 3-dimensional (3D). To solve this problem, we propose application of the time-of-flight (TOF) technique to DPECT as an enhancement. In this research, we used a Geant4 simulation to demonstrate the effectiveness of TOF in large 3D volume image reconstruction.


Author(s):  
Willem H.J. Andersen

Electron microscope design, and particularly the design of the imaging system, has reached a high degree of perfection. Present objective lenses perform up to their theoretical limit, while the whole imaging system, consisting of three or four lenses, provides very wide ranges of magnification and diffraction camera length with virtually no distortion of the image. Evolution of the electron microscope in to a routine research tool in which objects of steadily increasing thickness are investigated, has made it necessary for the designer to pay special attention to the chromatic aberrations of the magnification system (as distinct from the chromatic aberration of the objective lens). These chromatic aberrations cause edge un-sharpness of the image due to electrons which have suffered energy losses in the object.There exist two kinds of chromatic aberration of the magnification system; the chromatic change of magnification, characterized by the coefficient Cm, and the chromatic change of rotation given by Cp.


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