Characterization of time-of-flight double-photon Compton imaging system by simulation

2022 ◽  
Vol 17 (01) ◽  
pp. C01045
Author(s):  
Z. Zhihong ◽  
K. Shimazoe ◽  
H. Takahashi
Keyword(s):  
Image Reconstruction ◽  
Imaging System ◽  
Photon Emission ◽  
Time Of Flight ◽  
Emission Computed Tomography ◽  
Compton Imaging ◽  
3 Dimensional ◽  
3D Volume ◽  
Photon Emission Computed Tomography

Abstract Double-photon emission computed tomography (DPECT) has been proposed to overcome the disadvantage of a low signal-to-background ratio for conventional Compton imaging. This method has shown significant image reconstruction capability in the 2D plane. However, its performance is unsatisfactory when the field of view is 3-dimensional (3D). To solve this problem, we propose application of the time-of-flight (TOF) technique to DPECT as an enhancement. In this research, we used a Geant4 simulation to demonstrate the effectiveness of TOF in large 3D volume image reconstruction.

scholarly journals Time of flight dual photon emission computed tomography

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Chih-Chieh Chiang ◽  
Chun-Chao Chuang ◽  
Yu-Ching Ni ◽  
Meei-Ling Jan ◽  
Keh-Shih Chuang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Imaging System ◽  
Detection System ◽  
Photon Emission ◽  
Time Of Flight ◽  
Emission Computed Tomography ◽  
List Mode ◽  
Emission Computed ◽  
Photon Emission Computed Tomography

Abstract Time-of-flight dual photon emission computed tomography (TOF-DuPECT) is an imaging system that can obtain radionuclide distributions using time information recorded from two cascade-decay photons. The potential decay locations in the image space, a hyperbolic response curve, can be determined via time-difference-of-arrival (TDOA) estimations from two instantaneous coincidence photons. In this feasibility study, Monte Carlo simulations were performed to generate list-mode coincidence data. A full-ring positron emission tomography-like detection system geometry was built in the simulation environment. A contrast phantom and a Jaszczak-like phantom filled with Selenium-75 (Se-75) were used to evaluate the image quality. A TOF-DuPECT system with varying coincidence time resolution (CTR) was then evaluated. We used the stochastic origin ensemble (SOE) algorithm to reconstruct images from the recorded list-mode data. The results indicate that the SOE method can be successfully employed for the TOF-DuPECT system and can achieve acceptable image quality when the CTR is less than 100 ps. Therefore, the TOF-DuPECT imaging system is feasible. With the improvement of the detector with time, future implementations and applications of TOF-DuPECT are promising. Further quantitative imaging techniques such as attenuation and scatter corrections for the TOF-DuPECT system will be developed in future.

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