The Role of Prophylactic Antibiotics in Laparoscopic Cholecystectomy in Preventing Postoperative Infection: A Meta-Analysis

2011 ◽  
Vol 21 (4) ◽  
pp. 301-306 ◽  
Author(s):  
Rui-Cheng Yan ◽  
Shi-Qiang Shen ◽  
Zu-Bing Chen ◽  
Fu-Sheng Lin ◽  
Jan Riley
2008 ◽  
Vol 12 (11) ◽  
pp. 1847-1853 ◽  
Author(s):  
Abhishek Choudhary ◽  
Matthew L. Bechtold ◽  
Srinivas R. Puli ◽  
Mohamed O. Othman ◽  
Praveen K. Roy

2008 ◽  
Vol 134 (4) ◽  
pp. A-844-A-845
Author(s):  
Abhishek Choudhary ◽  
Matthew L. Bechtold ◽  
Craig Karpman ◽  
Srinivas R. Puli ◽  
Mohamed O. Othman ◽  
...  

Author(s):  
Ida Kotisalmi ◽  
Maija Hytönen ◽  
Antti A. Mäkitie ◽  
Markus Lilja

Abstract Purpose One of the most common complications after septoplasty is a postoperative infection. We investigated the number of postoperative infections and unplanned postoperative visits (UPV) in septoplasties with and without additional nasal surgery at our institution and evaluated the role of antibiotic prophylaxis. Methods We collected data of all consecutive 302 septoplasty or septocolumelloplasty patients operated during the year 2018 at the Department of Otorhinolaryngology-Head and Neck Surgery, HUS Helsinki University Hospital (Helsinki, Finland). Hospital charts were reviewed to record sociodemographic patient characteristics and clinical parameters regarding surgery and follow-up. Results Altogether 239 patients (79.1%) received pre- and/or postoperative prophylactic antibiotics and within this group 3.3% developed a postoperative infection. The infection rate in the non-prophylaxis group of 63 patients was 12.7% (p = 0.007). When all patients who received postoperative antibiotics were excluded, we found that the infection rate in the preoperative prophylaxis group was 3.8%, as opposed to an infection rate of 12.7% in the non-prophylaxis group (p = 0.013). When evaluating septoplasty with additional sinonasal surgery (n = 115) the rate of postoperative infection was 3.3% in the prophylaxis group and 16.7% in the non-prophylaxis group (p = 0.034). These results show a statistically significant stand-alone effect of preoperative prophylactic antibiotics in preventing postoperative infection in septoplasty, especially regarding additional sinonasal surgery. Conclusion The use of preoperative antibiotics as a prophylactic measure diminished statistically significantly the rate of infections and UPVs in septoplasty when all postoperative infections, superficial and mild ones included, were taken into account.


2015 ◽  
Vol 81 (5) ◽  
pp. AB417
Author(s):  
Bhupinder S. Romana ◽  
Sameer Siddique ◽  
Harathi Yandrapu ◽  
Prashanth Vennalaganti ◽  
Sreekar Vennelaganti ◽  
...  

2019 ◽  
Vol 114 (1) ◽  
pp. S1554-S1555
Author(s):  
Mahendran Jayaraj ◽  
Babu P. Mohan ◽  
Ranjit Makar ◽  
Ritika Ohri ◽  
Daisy S. Lankarani ◽  
...  

2020 ◽  
Vol 7 (5) ◽  
pp. 1580
Author(s):  
Renu Verma ◽  
Sushil Kumar Mittal ◽  
Navdeep Kumar Singla

Background: Elective gallbladder surgery is the most common abdominal surgical procedure. Antibiotic prophylaxis is a common conduct in open cholecystectomy, but there is ambiguity about the use of prophylactic antibiotics in laparoscopic cholecystectomy. Some surgeons suggest that the elimination of prophylactic antibiotics in patients undergoing elective laparoscopic cholecystectomy increase the incidence of postoperative infective complications but not to a statistically significant degree. The aim of this study was to evaluate the role of prophylactic antibiotics in laparoscopic cholecystectomy.Methods: A total of 100 patients were included and they were randomized in 2 groups of 50 each. Group A was given prophylactic intravenously (IV) antibiotic within 1 hour before surgery and group B was not given any antibiotics. Results were compared and data analyzed statistically using chi-square and t test. Complications in both the groups were compared.Results: Rate of surgical site infections were 6% (n=3) and 4% (n=2) in group A and B respectively; and the difference between them was not found statistically significant. All infections which occurred in present study were superficial surgical site infection. There was no evidence of deep-seated infections and none of the patients developed distant infection. There was no derangement in any of the biochemical parameter in this study.Conclusions: We were not able to demonstrate any significant benefit from addition of prophylactic antibiotics in elective laparoscopic cholecystectomy. 


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