scholarly journals Resuscitation with Valproic Acid Alters Inflammatory Genes in a Porcine Model of Combined Traumatic Brain Injury and Hemorrhagic Shock

2016 ◽  
Vol 33 (16) ◽  
pp. 1514-1521 ◽  
Author(s):  
Ted Bambakidis ◽  
Simone E. Dekker ◽  
Martin Sillesen ◽  
Baoling Liu ◽  
Craig N. Johnson ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Brain Injury ◽  
Hemorrhagic Shock ◽  
Porcine Model ◽  
Inflammatory Genes

Rapid valproic acid-induced modulation of the traumatic proteome in a porcine model of traumatic brain injury and hemorrhagic shock

2018 ◽  
Vol 228 ◽  
pp. 84-92 ◽  
Author(s):  
Michael Weykamp ◽  
Vahagn C. Nikolian ◽  
Isabel S. Dennahy ◽  
Gerald A. Higgins ◽  
Patrick E. Georgoff ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Brain Injury ◽  
Hemorrhagic Shock ◽  
Porcine Model

Valproic Acid Treatment Rapidly Modulates the Proteomic Profile in a Porcine Model of Hemorrhagic Shock and Traumatic Brain Injury

2017 ◽  
Vol 225 (4) ◽  
pp. S67
Author(s):  
Michael B. Weykamp ◽  
Vahagn C. Nikolian ◽  
Isabel S. Dennahy ◽  
Patrick E. Georgoff ◽  
Gerry A. Higgins ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Brain Injury ◽  
Hemorrhagic Shock ◽  
Acid Treatment ◽  
Porcine Model ◽  
Proteomic Profile

Pharmacologic modulation of cerebral metabolic derangement and excitotoxicity in a porcine model of traumatic brain injury and hemorrhagic shock

Surgery ◽  
2013 ◽  
Vol 154 (2) ◽  
pp. 234-243 ◽  
Author(s):  
John O. Hwabejire ◽  
Guang Jin ◽  
Ayesha M. Imam ◽  
Michael Duggan ◽  
Martin Sillesen ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Hemorrhagic Shock ◽  
Porcine Model ◽  
Metabolic Derangement ◽  
Pharmacologic Modulation

Valproic acid decreases brain lesion size and improves neurologic recovery in swine subjected to traumatic brain injury, hemorrhagic shock, and polytrauma

2017 ◽  
Vol 83 (6) ◽  
pp. 1066-1073 ◽  
Author(s):  
Vahagn C. Nikolian ◽  
Patrick E. Georgoff ◽  
Manjunath P. Pai ◽  
Isabel S. Dennahy ◽  
Kiril Chtraklin ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Brain Injury ◽  
Hemorrhagic Shock ◽  
Brain Lesion ◽  
Lesion Size ◽  
Neurologic Recovery

Valproic Acid Treatment Modulates the Inflammatory and Coagulation Proteome Following Traumatic Brain Injury and Hemorrhagic Shock

2019 ◽  
Vol 229 (4) ◽  
pp. S313
Author(s):  
Umar F. Bhatti ◽  
Aaron M. Williams ◽  
Vahagn C. Nikolian ◽  
Isabel S. Dennahy ◽  
Michael Weykamp ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Valproic Acid ◽  
Brain Injury ◽  
Hemorrhagic Shock ◽  
Acid Treatment
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