Canine Visceral Leishmaniasis in São Paulo, Brazil, the Most Populous City of South America: Isolation, Molecular Diagnosis, and Phylogenetic Inferences

2020 ◽  
Vol 20 (10) ◽  
pp. 768-772
Author(s):  
Arlei Marcili ◽  
Ryan Emiliano da Silva ◽  
Vilma Pereira da Costa ◽  
Fernanda A. Nieri-Bastos ◽  
Roberta Carvalho de Freitas e Azevedo ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
South America ◽  
Molecular Diagnosis ◽  
Sao Paulo ◽  
Canine Visceral Leishmaniasis ◽  
São Paulo

scholarly journals Description of six autochthonous cases of canine visceral leishmaniasis diagnosed in Pedregulho (São Paulo, Brazil)

2015 ◽  
Vol 24 (2) ◽  
pp. 216-219
Author(s):  
Cássia Regina de Abreu ◽  
Ana Cláudia Parpinelli ◽  
Romeika Reis de Lima ◽  
Luis Gustavo Gosuen Gonçalves Dias ◽  
Lucas de Freitas Pereira ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Clinical Signs ◽  
Sao Paulo ◽  
Sand Fly ◽  
Lutzomyia Longipalpis ◽  
Canine Visceral Leishmaniasis ◽  
São Paulo ◽  
Leishmania Chagasi ◽  
The City ◽  
Degrees Of Severity

Visceral leishmaniasis is an infectious disease of chronic, emerging and zoonotic nature that presents various degrees of severity. In Brazil, this illness is caused by Leishmania infantum (Leishmania chagasi), which is transmitted by the bite of the sand fly Lutzomyia longipalpis, and dogs are its main reservoir. Given the increasing spread of this disease across Brazil, the aim of this study was to report on six cases of canine visceral leishmaniasis, diagnosed in June 2013, in the city of Pedregulho, State of São Paulo, considered to be a non-endemic area and free of phlebotomine sand flies. The diagnosis was based on clinical signs of the patients and additional tests (serological and parasitological). It was concluded that the diagnosis of leishmaniasis is complex because the clinical signs are similar to other systemic diseases, thus justifying the importance of parasitological test of bone marrow, considered "gold standard", in the confirmation of the disease. In addition, the area was not, until now, considered risk place, despite notification.

scholarly journals Canine visceral leishmaniasis and Chagas disease among dogs in Araguaína, Tocantins

2013 ◽  
Vol 22 (2) ◽  
pp. 225-229 ◽  
Author(s):  
Arielle Nunes Morais ◽  
Marlos Gonçalves Sousa ◽  
Luciana Regina Meireles ◽  
Norival Kesper Jr. ◽  
Eufrosina Setsu Umezawa
Keyword(s):  
Visceral Leishmaniasis ◽  
Sao Paulo ◽  
Immunofluorescence Assay ◽  
Enzyme Linked Immunosorbent Assay ◽  
Canine Visceral Leishmaniasis ◽  
São Paulo ◽  
Reference Test ◽  
Serum Samples ◽  
Canine Population ◽  
De Medicina

The present study analyzed serum samples from 111 male and female dogs of various ages from the municipality of Araguaína in the State of Tocantins, Brazil. Serological diagnosis of canine visceral leishmaniasis (CVL) was initially performed at the Central Laboratory (Laboratório Central – LACEN) of Araguaína, resulting in 61 positive samples by an indirect immunofluorescence assay (IIFA) (≥1:40) and 50 non-reactive samples. The same samples were analyzed at the São Paulo Institute of Tropical Medicine (Instituto de Medicina Tropical de São Paulo – IMTSP) by an enzyme-linked-immunosorbent assay (ELISA), resulting in 57 positive samples (51.35%) and 54 negative samples (48.64%). The Kappa coefficient of agreement between the tests was 0.74. The serum samples were also subjected to a diagnostic assay for Trypanosoma cruzi(Trypomastigote Excreted/Secreted Antigens -TESA-blot) that detected five suspect animals; three of those animals were positive for leishmaniasis by ELISA but negative by IIFA. These findings suggest that the canine population of Araguaína may be simultaneously infected withLeishmania chagasi and T. cruzi. The results obtained demonstrate the difficulty of using serology to detect CVL, thus emphasizing the necessity for a reference test to diagnose CVL, particularly in regions where the infection is endemic.

scholarly journals The first canine visceral leishmaniasis outbreak in Campinas, State of São Paulo Southeastern Brazil

2014 ◽  
Vol 47 (3) ◽  
pp. 385-388 ◽  
Author(s):  
Andrea Paula Bruno von Zuben ◽  
Rodrigo Nogueira Angerami ◽  
Claudio Castagna ◽  
Marisa Bevilacqua Denardi Baldini ◽  
Maria Rita Donalisio
Keyword(s):  
Visceral Leishmaniasis ◽  
Sao Paulo ◽  
Southeastern Brazil ◽  
Canine Visceral Leishmaniasis ◽  
São Paulo

scholarly journals Dispersal of Lutzomyia longipalpis and expansion of canine and human visceral leishmaniasis in São Paulo State, Brazil

Acta Tropica ◽  
2016 ◽  
Vol 164 ◽  
pp. 233-242 ◽  
Author(s):  
Agda Maria Oliveira ◽  
Carolina Portugal Vieira ◽  
Margareth Regina Dibo ◽  
Marluci Monteiro Guirado ◽  
Lilian Aparecida Colebrusco Rodas ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Sao Paulo ◽  
Lutzomyia Longipalpis ◽  
São Paulo ◽  
Paulo State ◽  
Human Visceral Leishmaniasis ◽  
São Paulo State

scholarly journals The shadows of a ghost: a survey of canine leishmaniasis in Presidente Prudente and its spatial dispersion in the western region of São Paulo state, an emerging focus of visceral leishmaniasis in Brazil

2015 ◽  
Vol 11 (1) ◽  
Author(s):  
Lourdes Aparecida Zampieri D’Andrea ◽  
Elivelton da Silva Fonseca ◽  
Luiz Euribel Prestes-Carneiro ◽  
Raul Borges Guimarães ◽  
Renata Corrêa Yamashita ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Spatial Dispersion ◽  
Sao Paulo ◽  
Canine Leishmaniasis ◽  
Western Region ◽  
São Paulo ◽  
Paulo State ◽  
São Paulo State ◽  
The Western Region

scholarly journals Space-time cluster analysis of American visceral leishmaniasis in Bauru, São Paulo State, Brazil

2012 ◽  
Vol 28 (10) ◽  
pp. 1949-1964 ◽  
Author(s):  
Vanessa Aparecida Feijó de Souza ◽  
Luiz Ricardo Paes de Barros Cortez ◽  
Ricardo Augusto Dias ◽  
Marcos Amaku ◽  
José Soares Ferreira Neto ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Urban Areas ◽  
Sao Paulo ◽  
Space Time ◽  
São Paulo ◽  
Prevention Measures ◽  
Paulo State ◽  
Positive Tendency ◽  
São Paulo State ◽  
The City

A space-time analysis of American visceral leishmaniasis (AVL) in humans in the city of Bauru, São Paulo State, Brazil was carried out based on 239 cases diagnosed between June 2003 and October 2008. Spatial analysis of the disease showed that cases occurred especially in the city's urban areas. AVL annual incidence rates were calculated, demonstrating that the highest rate occurred in 2006 (19.55/100,000 inhabitants). This finding was confirmed by the time series analysis, which also showed a positive tendency over the period analyzed. The present study allows us to conclude that the disease was clustered in the Southwest side of the city in 2006, suggesting that this area may require special attention with regard to control and prevention measures.

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