Reduction of Marek's Disease Virus Infection by Toll-Like Receptor Ligands in Chicken Embryo Fibroblast Cells

2018 ◽  
Vol 31 (5) ◽  
pp. 389-396 ◽  
Author(s):  
Jegarubee Bavananthasivam ◽  
Raveendra R. Kulkarni ◽  
Leah Read ◽  
Shayan Sharif
Keyword(s):  
Virus Infection ◽  
Disease Virus ◽  
Chicken Embryo ◽  
Chicken Embryo Fibroblast ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Fibroblast Cells ◽  
Marek’S Disease Virus ◽  
Toll Like Receptor ◽  
Receptor Ligands

Interactions between Marek’s disease virus Rispens/CVI988 vaccine strain and adenovirus field strain in chicken embryo fibroblast (CEF) cultures

2014 ◽  
Vol 17 (1) ◽  
pp. 3-8 ◽  
Author(s):  
J.S. Niczyporuk ◽  
G. Woźniakowski ◽  
H. Czekaj ◽  
E. Samorek-Salamonowicz
Keyword(s):  
Disease Virus ◽  
Vaccine Strain ◽  
Chicken Embryo ◽  
Chicken Embryo Fibroblast ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Field Strain ◽  
Adenovirus Infection ◽  
Marek’S Disease Virus ◽  
Pp38 Gene

AbstractThe aim of the study was to determine the influence of adenovirus infection on the replication of Marek’s disease virus vaccine strain Rispens/CVI988 during in vitro co-infection studies. Adenovirus field strain JN-5/10j was isolated from sick chickens. The study was conducted in chicken embryo fibroblast cultures (CEF). Monolayers of CEFs were infected with Rispens strain and field adenovirus strain JN-5/10j with different doses (101.0-103.0TCID50) in the following manner: a) simultaneously, b) first, infection with Rispens strain and after 24 h infection with adenovirus strain JN-5/10j and c) infection with adenovirus strain JN-5/10j 24 h before infection with Rispens strain. After 18, 24, 48, 72, and 96 h of incubation, the copy number of the pp38 gene of Rispens strain was determined using Real-time PCR. The results indicated that the Adenovirus infection before the infection with Rispens strain reduced the replication of the pp38 gene after 48 h by 2 log10.

scholarly journals Toll-like receptor 3 pathway restricts Marek’s disease virus infection

Oncotarget ◽  
2017 ◽  
Vol 8 (41) ◽  
pp. 70847-70853 ◽  
Author(s):  
Haitao Zou ◽  
Ruixue Su ◽  
Jing Ruan ◽  
Hongxia Shao ◽  
Kun Qian ◽  
...  
Keyword(s):  
Virus Infection ◽  
Disease Virus ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Toll Like Receptor

In ovo administration of Toll-like receptor ligands encapsulated in PLGA nanoparticles impede tumor development in chickens infected with Marek’s disease virus

Vaccine ◽  
2018 ◽  
Vol 36 (28) ◽  
pp. 4070-4076 ◽  
Author(s):  
Jegarubee Bavananthasivam ◽  
Tamiru N. Alkie ◽  
Jake Astill ◽  
Mohamed Faizal Abdul-Careem ◽  
Sarah K. Wootton ◽  
...  
Keyword(s):  
Disease Virus ◽  
Tumor Development ◽  
Plga Nanoparticles ◽  
Marek's Disease Virus ◽  
Marek's Disease ◽  
Marek’S Disease Virus ◽  
Marek’S Disease ◽  
Toll Like Receptor ◽  
Receptor Ligands ◽  
In Ovo
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