Intratumor Variation in Cell Proliferation in Breast Carcinoma as Determined by Antiproliferating Cell Nuclear Antigen Monoclonal Antibody and Automated Image Analysis

1993 ◽  
Vol 99 (3) ◽  
pp. 226-231 ◽  
Author(s):  
Sanna M. Siitonen ◽  
Jorma J. Isola ◽  
Immo S. Rantala ◽  
Heikki J. Helin
Keyword(s):  
Monoclonal Antibody ◽  
Cell Proliferation ◽  
Image Analysis ◽  
Breast Carcinoma ◽  
Automated Image Analysis ◽  
Nuclear Antigen

scholarly journals An advanced automated image analysis model for scoring of ER, PR, HER-2 and Ki-67 in breast carcinoma

IEEE Access ◽  
2020 ◽  
pp. 1-1
Author(s):  
Min Feng ◽  
Jie Chen ◽  
Xuhui Xiang ◽  
Yang Deng ◽  
Yanyan Zhou ◽  
...  
Keyword(s):  
Image Analysis ◽  
Breast Carcinoma ◽  
Automated Image Analysis ◽  
Analysis Model ◽  
Ki 67 ◽  
Her 2

Growth Fraction of Colorectal Carcinoma (Ki67): A Comparative Study

1992 ◽  
Vol 7 (2) ◽  
pp. 93-96 ◽  
Author(s):  
A. Benetti ◽  
A. Berenzi ◽  
P. Grigolato
Keyword(s):  
Monoclonal Antibody ◽  
Cell Proliferation ◽  
Colorectal Carcinoma ◽  
Nuclear Antigen ◽  
Growth Fraction ◽  
Immunoperoxidase Technique ◽  
Ki67 Staining ◽  
A Cell ◽  
Colorectal Adenocarcinomas ◽  
Age And Sex

We studied the growth fraction of55 resected colorectal adenocarcinomas by means of a three-step immunoperoxidase technique (avidin-biotin-peroxidase) using the monoclonal antibody Ki67 directed against a cell proliferation-associated nuclear antigen. The percentage of Ki67-positive cells was evaluated independently by two observers, and a Ki67 score was obtained for each case. No correlation was observed between Ki67 staining and patient's age and sex, tumor size and localization or grading and staging according to Dukes’ method (modified by Astler-Coller and Turnbull). The growth fraction showed extreme heterogeneity in the cases examined, within each grade of differentiation.

scholarly journals Proliferating cell nuclear antigen (PCNA) expressed in human leptomeninges.

1996 ◽  
Vol 44 (11) ◽  
pp. 1261-1265 ◽  
Author(s):  
H Funato ◽  
M Yoshimura ◽  
Y Ito ◽  
R Okeda ◽  
Y Ihara
Keyword(s):  
Monoclonal Antibody ◽  
Cell Proliferation ◽  
Smooth Muscle ◽  
Proliferating Cell Nuclear Antigen ◽  
Normal Subjects ◽  
Nuclear Antigen ◽  
Ependymal Cells ◽  
Ki 67 ◽  
Proliferating Cell ◽  
Strong Immunoreactivity

Here we report on the presence of proliferating cell nuclear antigen (PCNA) in human leptomeninges from 35 normal subjects with ages ranging from 57 to 94 years. Strong immunoreactivity with PC10 (a monoclonal antibody to PCNA) was detected in the nuclei of meningothelial cells, smooth muscle cells of leptomeningeal vessels, and ependymal cells. An immunoblot of leptomeningeal homogenate with PC10 showed the presence of a single band at 35 KD, the expected molecular mass of PCNA. Ki-67, another marker for cell proliferation, was undetectable in human leptomeninges. These observations point to isolated PCNA expression in tissue in which cells are not actively proliferating.

scholarly journals Ovarian Follicle Counts Using Proliferating Cell Nuclear Antigen (PCNA) and Semi-Automated Image Analysis in Rats

2008 ◽  
Vol 36 (5) ◽  
pp. 674-679 ◽  
Author(s):  
Catherine A. Picut ◽  
Cynthia L. Swanson ◽  
Kathryn L. Scully ◽  
Vern C. Roseman ◽  
Regina F. Parker ◽  
...  
Keyword(s):  
Image Analysis ◽  
Proliferating Cell Nuclear Antigen ◽  
Ovarian Follicle ◽  
Automated Image Analysis ◽  
Nuclear Antigen ◽  
Proliferating Cell

scholarly journals Quantitative Automated Image Analysis System with Automated Debris Filtering for the Detection of Breast Carcinoma Cells

2011 ◽  
Vol 55 (3) ◽  
pp. 271-280 ◽  
Author(s):  
David T. Martin ◽  
Sergio Sandoval ◽  
Casey N. Ta ◽  
Manuel E. Ruidiaz ◽  
Maria Jose Cortes-Mateos ◽  
...  
Keyword(s):  
Image Analysis ◽  
Breast Carcinoma ◽  
Carcinoma Cells ◽  
Automated Image Analysis ◽  
Image Analysis System ◽  
Breast Carcinoma Cells ◽  
Analysis System
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