Alveolar Soft Part Sarcoma Presenting as a Uterine Polyp

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S37-S37
Author(s):  
Mariangela Gomez ◽  
Kerry Whiting
Keyword(s):  
Soft Tissue Tumor ◽  
Soft Part ◽  
Female Genital Tract ◽  
Alveolar Soft Part Sarcoma ◽  
Complete Excision ◽  
Molecular Features ◽  
Malignant Soft Tissue Tumor ◽  
Pathological Evaluation ◽  
Malignant Soft Tissue ◽  
Female Genital

Abstract Background Alveolar soft part sarcoma (ASPS) is a rare malignant soft tissue tumor, mainly localized in the extremities, occurring principally in adolescents and young adults. ASPS is uncommon in the female genital tract. Case report We here report a case of ASPS in a 20-year-old nullipara, presenting with vaginal bleeding and profound anemia requiring blood transfusions. Ultrasonographic examination revealed a polyp in the lower uterine segment. Surgical resection of the polyp was performed, and pathological evaluation showed the typical histological, immunohistochemical, and molecular features consistent with ASPS. At the time of this report, the patient was scheduled for total hysterectomy with promising results. Conclusion Given the infrequency of ASPS, pathological evaluation is or utmost importance in order to establish an accurate diagnosis. When presenting as a primary tumor, complete excision is fundamental in the treatment.

scholarly journals Alveolar soft part sarcoma presenting as a uterine polyp: A case report

2020 ◽  
Vol 8 ◽  
pp. 2050313X2091059
Author(s):  
Mariangela Gomez ◽  
Kerry Whiting ◽  
Rana Naous
Keyword(s):  
Case Report ◽  
Soft Part ◽  
Female Genital Tract ◽  
Alveolar Soft Part Sarcoma ◽  
Molecular Features ◽  
Malignant Soft Tissue Tumor ◽  
Pathological Evaluation ◽  
Malignant Soft Tissue ◽  
Sarcoma Patient ◽  
Female Genital

Alveolar soft part sarcoma is a rare malignant soft tissue tumor, mainly localized in the extremities and occurring principally in adolescents and young adults. Alveolar soft part sarcoma are uncommon in the female genital tract. We here report a case of alveolar soft part sarcoma in a 20-year-old nullipara, presenting with vaginal bleeding and profound anemia requiring blood transfusions. Ultrasonographic examination revealed a polyp in the lower uterine segment. Surgical resection of the polyp was performed, and pathological evaluation showed typical histological, immunohistochemical, and molecular features consistent with alveolar soft part sarcoma. Patient underwent for total hysterectomy. Currently, she follows up with her surgeon and has no new complains. Given the infrequency of alveolar soft part sarcoma, this case report raises the awareness of alveolar soft part sarcoma as one of the entities to consider when confronted with a uterine polyp in a young patient.

Alveolar soft-part sarcoma of the female genital tract

1987 ◽  
Vol 240 (2) ◽  
pp. 125-129 ◽  
Author(s):  
Juri Kopolovic ◽  
David B. Weiss ◽  
Leah Dolberg ◽  
Amnon Brezinsky ◽  
Zvi Ne'eman ◽  
...  
Keyword(s):  
Genital Tract ◽  
Soft Part ◽  
Female Genital Tract ◽  
Alveolar Soft Part Sarcoma ◽  
Female Genital

Alveolar Soft-Part Sarcoma of the Female Genital Tract

1995 ◽  
Vol 14 (4) ◽  
pp. 283-292 ◽  
Author(s):  
Gunnlaugur P. Nielsen ◽  
Esther Oliva ◽  
Robert H. Young ◽  
Andrew E. Rosenberg ◽  
G. Richard Dickersin ◽  
...  
Keyword(s):  
Genital Tract ◽  
Soft Part ◽  
Female Genital Tract ◽  
Alveolar Soft Part Sarcoma ◽  
Female Genital

Primary Alveolar Soft-Part Sarcoma of the Liver: Anomalous Presentation of a Rare Disease

2008 ◽  
Vol 74 (1) ◽  
pp. 43-46 ◽  
Author(s):  
Kyle K. Shaddix ◽  
G. Peter Fakhre ◽  
William W. Nields ◽  
Jeffery L. Steers ◽  
Winston R. Hewitt ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissues ◽  
Soft Part ◽  
Case Reports ◽  
Pediatric Population ◽  
Female Genital Tract ◽  
Soft Tissue Sarcomas ◽  
Alveolar Soft Part Sarcoma ◽  
Anatomic Locations ◽  
Female Genital

Alveolar soft-part sarcoma is a highly vascular soft-tissue tumor that is uniformly malignant. It comprises less than 1 per cent of all soft-tissue sarcomas. Patients with alveolar soft-part sarcoma most frequently are aged 15 to 35 years, and the soft tissues of the lower extremities typically are affected. In the pediatric population, it most frequently occurs in the head and neck and particularly affects the tongue and orbit. Alveolar soft-part sarcoma has been described as a primary lesion in the trunk, upper extremities, and retroperitoneum; more novel locations include the mediastinum, female genital tract, stomach, bone, and larynx. Numerous case reports describe alveolar soft-part sarcoma in diverse anatomic locations, but this report is, to our knowledge, the first documentation of primary alveolar soft-part sarcoma of the liver. We describe a 47-year-old woman with such a manifestation. Despite surgical resection and numerous chemotherapeutic regimens, this patient had widespread metastasis and died approximately 2 years after the diagnosis was established.

Alveolar Soft Part Sarcoma of the Female Genital Tract

2017 ◽  
Vol 41 (5) ◽  
pp. 622-632 ◽  
Author(s):  
J. Kenneth Schoolmeester ◽  
Joseph Carlson ◽  
Gary L. Keeney ◽  
Karen J. Fritchie ◽  
Esther Oliva ◽  
...  
Keyword(s):  
Genital Tract ◽  
Soft Part ◽  
Female Genital Tract ◽  
Alveolar Soft Part Sarcoma ◽  
Female Genital

Preoperative evaluation of intraoperative blood loss during malignant soft tissue tumor resection by ultrasonography

2018 ◽  
Vol 23 (2) ◽  
pp. 403-407 ◽  
Author(s):  
Takeshi Morii ◽  
Tomonori Kishino ◽  
Naoko Shimamori ◽  
Mitsue Motohashi ◽  
Hiroaki Ohnishi ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Blood Loss ◽  
Soft Tissue Tumor ◽  
Preoperative Evaluation ◽  
Tumor Resection ◽  
Intraoperative Blood Loss ◽  
Tissue Tumor ◽  
Malignant Soft Tissue Tumor ◽  
Malignant Soft Tissue

Synovial Sarcoma of the Brachial Plexus

Neurosurgery ◽  
2011 ◽  
Vol 70 (5) ◽  
pp. 1329-1333 ◽  
Author(s):  
Farhad Pirouzmand ◽  
Kavya Kommaraju ◽  
Kenneth J. Craddock ◽  
David Howarth
Keyword(s):  
Brachial Plexus ◽  
Synovial Sarcoma ◽  
Soft Tissue Tumor ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Relevant Literature ◽  
Adjuvant Radiation ◽  
Malignant Soft Tissue Tumor ◽  
Malignant Soft Tissue ◽  
Firm Mass

Abstract BACKGROUND AND IMPORTANCE: Synovial sarcoma (SS) is a malignant soft-tissue tumor that rarely involves brachial plexus. The authors report a case of brachial plexus SS and review the relevant literature. CLINICAL PRESENTATION: A 53-year-old woman presented with gradually enlarging right subclavicular mass over 5 years associated with sharp aching pain radiating down toward the radial 3 fingers. On examination, she had a corresponding firm mass in the supraclavicular region with a positive Tinel sign. There was no objective neurological deficit. She underwent partial excision of this mass without any further adjuvant radiation or chemotherapy. Pathology was consistent with SS. CONCLUSION: Lack of any recurrence in this case 6 years after incomplete excision with no adjuvant therapy suggests slow clinical course in some of these sarcomas.

Suppression of IL-6 production and proliferation by blocking STAT3 activation in malignant soft tissue tumor cells

2006 ◽  
Vol 231 (2) ◽  
pp. 176-184 ◽  
Author(s):  
Takanori Shouda ◽  
Koji Hiraoka ◽  
Setsuro Komiya ◽  
Tetsuya Hamada ◽  
Michihisa Zenmyo ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Tumor Cells ◽  
Soft Tissue Tumor ◽  
Tissue Tumor ◽  
Malignant Soft Tissue Tumor ◽  
Malignant Soft Tissue
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