Synovial Sarcoma of the Brachial Plexus

Neurosurgery ◽  
2011 ◽  
Vol 70 (5) ◽  
pp. 1329-1333 ◽  
Author(s):  
Farhad Pirouzmand ◽  
Kavya Kommaraju ◽  
Kenneth J. Craddock ◽  
David Howarth
Keyword(s):  
Brachial Plexus ◽  
Synovial Sarcoma ◽  
Soft Tissue Tumor ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Relevant Literature ◽  
Adjuvant Radiation ◽  
Malignant Soft Tissue Tumor ◽  
Malignant Soft Tissue ◽  
Firm Mass

Abstract BACKGROUND AND IMPORTANCE: Synovial sarcoma (SS) is a malignant soft-tissue tumor that rarely involves brachial plexus. The authors report a case of brachial plexus SS and review the relevant literature. CLINICAL PRESENTATION: A 53-year-old woman presented with gradually enlarging right subclavicular mass over 5 years associated with sharp aching pain radiating down toward the radial 3 fingers. On examination, she had a corresponding firm mass in the supraclavicular region with a positive Tinel sign. There was no objective neurological deficit. She underwent partial excision of this mass without any further adjuvant radiation or chemotherapy. Pathology was consistent with SS. CONCLUSION: Lack of any recurrence in this case 6 years after incomplete excision with no adjuvant therapy suggests slow clinical course in some of these sarcomas.

scholarly journals Embryonal Rhabdomyosarcoma with Posttherapy Cytodifferentiation and Aggressive Clinical Course

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Maniraj Jeyaraju ◽  
Regina Ann Macatangay ◽  
Ashley Taylor-King Munchel ◽  
Teresa Anne York ◽  
Elizabeth A. Montgomery ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Clinical Course ◽  
Good Prognosis ◽  
Embryonal Rhabdomyosarcoma ◽  
Clinicopathologic Features ◽  
Malignant Soft Tissue Tumor ◽  
Clinicopathologic Factors ◽  
Aggressive Clinical Course ◽  
Malignant Soft Tissue

Rhabdomyosarcoma is the most common soft tissue sarcoma in children and adolescents. Embryonal rhabdomyosarcoma (ERMS), its most common subtype, is a malignant soft tissue tumor with morphologic and immunophenotypic features of embryonic skeletal muscle. The histologic findings in ERMS typically include a range of differentiation in rhabdomyoblasts from primitive to terminally differentiated forms, and the latter become more prominent after chemotherapy-induced cytodifferentiation. Several reports have shown therapy-related cytodifferentiation to portend a good prognosis in ERMS. We discuss the case of a pediatric patient who presented with ERMS of the orbit. Although her tumor showed extensive posttreatment cytodifferentiation and several other good prognostic clinicopathologic factors, it pursued an aggressive course, resulting in early metastasis and death. This case represents an unusual course and may be instructive as to the clinicopathologic features impacting prognostication, and ultimately the biology, of this aggressive family of tumors.

Preoperative evaluation of intraoperative blood loss during malignant soft tissue tumor resection by ultrasonography

2018 ◽  
Vol 23 (2) ◽  
pp. 403-407 ◽  
Author(s):  
Takeshi Morii ◽  
Tomonori Kishino ◽  
Naoko Shimamori ◽  
Mitsue Motohashi ◽  
Hiroaki Ohnishi ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Blood Loss ◽  
Soft Tissue Tumor ◽  
Preoperative Evaluation ◽  
Tumor Resection ◽  
Intraoperative Blood Loss ◽  
Tissue Tumor ◽  
Malignant Soft Tissue Tumor ◽  
Malignant Soft Tissue

Alveolar Soft Part Sarcoma Presenting as a Uterine Polyp

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S37-S37
Author(s):  
Mariangela Gomez ◽  
Kerry Whiting
Keyword(s):  
Soft Tissue Tumor ◽  
Soft Part ◽  
Female Genital Tract ◽  
Alveolar Soft Part Sarcoma ◽  
Complete Excision ◽  
Molecular Features ◽  
Malignant Soft Tissue Tumor ◽  
Pathological Evaluation ◽  
Malignant Soft Tissue ◽  
Female Genital

Abstract Background Alveolar soft part sarcoma (ASPS) is a rare malignant soft tissue tumor, mainly localized in the extremities, occurring principally in adolescents and young adults. ASPS is uncommon in the female genital tract. Case report We here report a case of ASPS in a 20-year-old nullipara, presenting with vaginal bleeding and profound anemia requiring blood transfusions. Ultrasonographic examination revealed a polyp in the lower uterine segment. Surgical resection of the polyp was performed, and pathological evaluation showed the typical histological, immunohistochemical, and molecular features consistent with ASPS. At the time of this report, the patient was scheduled for total hysterectomy with promising results. Conclusion Given the infrequency of ASPS, pathological evaluation is or utmost importance in order to establish an accurate diagnosis. When presenting as a primary tumor, complete excision is fundamental in the treatment.

Suppression of IL-6 production and proliferation by blocking STAT3 activation in malignant soft tissue tumor cells

2006 ◽  
Vol 231 (2) ◽  
pp. 176-184 ◽  
Author(s):  
Takanori Shouda ◽  
Koji Hiraoka ◽  
Setsuro Komiya ◽  
Tetsuya Hamada ◽  
Michihisa Zenmyo ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Tumor Cells ◽  
Soft Tissue Tumor ◽  
Tissue Tumor ◽  
Malignant Soft Tissue Tumor ◽  
Malignant Soft Tissue

scholarly journals Free Muscle Transplantation for the Treatment of Malignant Soft tissue Tumor in the Forearm. A Cass Report.

1992 ◽  
Vol 40 (4) ◽  
pp. 1586-1588
Author(s):  
Mitsuhiro Kimura ◽  
Kazuteru Doi ◽  
Kazuhiro Sakai ◽  
Kouichirou Ihara ◽  
Tetsurou Kishimoto ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Tumor ◽  
Muscle Transplantation ◽  
Tissue Tumor ◽  
Malignant Soft Tissue Tumor ◽  
Free Muscle Transplantation ◽  
Malignant Soft Tissue

scholarly journals A Challenging Giant Dermatofibrosarcoma Protuberans on the Face

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Gimena Castro Pérez ◽  
Cintia Arias ◽  
Paula Luna ◽  
Irene Sorín ◽  
Luis Daniel Mazzuoccolo
Keyword(s):  
Local Recurrence ◽  
Head And Neck ◽  
Soft Tissue Tumor ◽  
Dermatofibrosarcoma Protuberans ◽  
Low Grade ◽  
Total Head ◽  
Malignant Soft Tissue Tumor ◽  
The Face ◽  
Subcutaneous Tissues ◽  
Malignant Soft Tissue

Dermatofibrosarcoma protuberans (DFSP) is a malignant fibrohistiocytic tumor that appears exclusively on the skin. It is a low-grade malignant soft tissue tumor of subcutaneous tissues that has a propensity for local recurrence but seldom metastasizes. It may rarely occur on the head and neck accounting for less than one percent of total head and neck malignancies. We present a man with a giant DFSP on the face. Oncological, functional, and aesthetic aspects are set forth.

PEDIATRIC INTRADURAL EXTRAMEDULLARY SYNOVIAL SARCOMA

Neurosurgery ◽  
2006 ◽  
Vol 59 (6) ◽  
pp. E1339-E1339 ◽  
Author(s):  
Stephanie Greene ◽  
Douglas S. Hawkins ◽  
Joe C. Rutledge ◽  
Karen D. Tsuchiya ◽  
James Douglas ◽  
...  
Keyword(s):  
Synovial Sarcoma ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Leptomeningeal Metastasis ◽  
Magnetic Resonance Imaging Scan ◽  
Rapid Progression ◽  
Resonance Imaging ◽  
Intracranial Metastases ◽  
Intradural Extramedullary ◽  
Resonance Imaging Scan

Abstract OBJECTIVE The diagnosis of intradural synovial sarcoma has not been previously published. This report provides a summary of the literature on this tumor and on tumors arising in this location, as well as a description of this patient's clinical course. CLINICAL PRESENTATION An 11-year-old girl presented with back pain and radiculopathy. A magnetic resonance imaging scan of the spine revealed a spinal intradural, extramedullary mass at L2–L4 and four additional nodules of enhancement. INTERVENTION The mass was nearly totally resected. Radiation and chemotherapy were administered. Intracranial metastases became evident during treatment. The patient died of the disease 14 months after diagnosis. CONCLUSION The rapid progression of leptomeningeal metastasis despite maximal treatment demonstrates the aggressive nature of the tumor and the need for further study.

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