scholarly journals A phase I first-in-human, dose-escalation and expansion study to evaluate the safety and tolerability of NUC-3373 in patients with locally advanced, unresectable or metastatic solid malignancies

2018 ◽  
Vol 29 ◽  
pp. viii145
Author(s):  
S. Blagden ◽  
P. Spiliopoulou ◽  
L. Spiers ◽  
C. Gnanaranjan ◽  
C. Qi ◽  
...  
Keyword(s):  
Phase I ◽  
Dose Escalation ◽  
Locally Advanced ◽  
Human Dose ◽  
Solid Malignancies

Abstract CT214: ATRiUM: A first-in-human dose escalation phase I trial of ceralasertib (AZD6738) and gemcitabine as combination therapy

2021 ◽  
Author(s):  
Bruno Henrique de Paula ◽  
Bristi Basu ◽  
Adrian Mander ◽  
Josephine Khan ◽  
Purity Bundi ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Phase I ◽  
Dose Escalation ◽  
Phase I Trial ◽  
Human Dose

Phase I Dose-Escalation and Pharmacokinetic Study of Intravenous Aflibercept in Combination with Docetaxel, Cisplatin, and 5-Fluorouracil in Patients with Advanced Solid Malignancies

Oncology ◽  
2015 ◽  
Vol 90 (1) ◽  
pp. 10-20 ◽  
Author(s):  
Rastislav Bahleda ◽  
Jackie Baker ◽  
Christophe Massard ◽  
Sirish M. Gadgeel ◽  
Jane E. Rogers ◽  
...  
Keyword(s):  
Phase I ◽  
Pharmacokinetic Study ◽  
Dose Escalation ◽  
Solid Malignancies

Concomitant boost dose escalation plus large-field preoperative chemoradiation in locally advanced carcinoma of the uterine cervix: Results of a phase I study (LARA-CC-1)

2010 ◽  
Vol 118 (2) ◽  
pp. 128-133 ◽  
Author(s):  
Gabriella Macchia ◽  
Gabriella Ferrandina ◽  
Francesco Deodato ◽  
Valeria Ruggieri ◽  
Mariangela Massaccesi ◽  
...  
Keyword(s):  
Phase I ◽  
Dose Escalation ◽  
Uterine Cervix ◽  
Phase I Study ◽  
Locally Advanced ◽  
Preoperative Chemoradiation ◽  
Large Field ◽  
Advanced Carcinoma ◽  
Concomitant Boost ◽  
Boost Dose

scholarly journals Phase I, First‐in‐Human, Dose‐Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Vorolanib in Patients with Advanced Solid Tumors

2018 ◽  
Vol 24 (4) ◽  
pp. 455 ◽  
Author(s):  
Johanna C. Bendell ◽  
Manish R. Patel ◽  
Kathleen N. Moore ◽  
Cynthia C. Chua ◽  
Hendrik‐Tobias Arkenau ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study ◽  
Human Dose
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