Randomized phase 2 trial of chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: CAO/ARO/AIO-12

Phase 2 ◽

Phase 2 Trial ◽

Total Neoadjuvant Therapy ◽

Randomized Phase 2

Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer

JAMA Oncology ◽

10.1001/jamaoncol.2021.5445 ◽

2021 ◽

pp. e215445

Author(s):

Emmanouil Fokas ◽

Anke Schlenska-Lange ◽

Bülent Polat ◽

Gunther Klautke ◽

Gerhard G. Grabenbauer ◽

...

Keyword(s):

Rectal Cancer ◽

Neoadjuvant Therapy ◽

Locally Advanced ◽

Advanced Rectal Cancer ◽

Commentary on: “Randomized Phase II Trial of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: CAO/ARO/AIO-12”

International Journal of Colorectal Disease ◽

10.1007/s00384-019-03364-5 ◽

2019 ◽

Vol 34 (9) ◽

pp. 1617-1618

Author(s):

Francesca De Felice ◽

Daniela Musio ◽

Vincenzo Tombolini ◽

Enrico Cortesi

Keyword(s):

Rectal Cancer ◽

Neoadjuvant Therapy ◽

Phase Ii ◽

Phase Ii Trial ◽

Locally Advanced ◽

Advanced Rectal Cancer ◽

Randomized Phase Ii ◽

Preoperative Chemoradiation With a Simultaneous Integrated Boost Compared to Regular Preoperative Chemoradiation for Locally Advanced Rectal Cancer: Interim Analysis of a Randomized Phase 2 Trial (NCT02195141)

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2015.07.303 ◽

2015 ◽

Vol 93 (3) ◽

pp. S127

Author(s):

H. Ren ◽

Y. Tang ◽

J. Jin ◽

N. Li ◽

H. Fang ◽

...

Keyword(s):

Rectal Cancer ◽

Interim Analysis ◽

Locally Advanced ◽

Advanced Rectal Cancer ◽

Preoperative Chemoradiation ◽

Phase 2 ◽

Phase 2 Trial ◽

Integrated Boost ◽

Randomized Phase 2

A Randomized Phase 2 Trial of Consolidation Chemotherapy After Preoperative Chemoradiation Therapy Versus Chemoradiation Therapy Alone for Locally Advanced Rectal Cancer: KCSG CO 14-03

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2018.04.013 ◽

2018 ◽

Vol 101 (4) ◽

pp. 889-899 ◽

Cited By ~ 7

Author(s):

Sun Young Kim ◽

Jungnam Joo ◽

Tae Won Kim ◽

Yong Sang Hong ◽

Jeong Eun Kim ◽

...

Keyword(s):

Locally Advanced ◽

Advanced Rectal Cancer ◽

Preoperative Chemoradiation ◽

Chemoradiation Therapy ◽

Phase 2 ◽

Phase 2 Trial ◽

Preoperative Chemoradiation Therapy ◽

Randomized Phase 2

Comparative Effectiveness of Total Neoadjuvant Therapy Versus Standard Adjuvant Chemotherapy for Locally Advanced Rectal Cancer

Clinical Colorectal Cancer ◽

10.1016/j.clcc.2021.01.001 ◽

2021 ◽

Author(s):

Shun Yu ◽

Ronac Mamtani ◽

Mark H. O'Hara ◽

Peter J. O'Dwyer ◽

Ofer Margalit ◽

...

Keyword(s):

Rectal Cancer ◽

Adjuvant Chemotherapy ◽

Neoadjuvant Therapy ◽

Comparative Effectiveness ◽

Locally Advanced ◽

Advanced Rectal Cancer ◽

LBA P-298 Response to total neoadjuvant therapy and survival in patients with early onset locally advanced rectal cancer

Annals of Oncology ◽

10.1016/j.annonc.2021.06.013 ◽

2021 ◽

Vol 32 ◽

pp. S228

Author(s):

M. Lumish ◽

E. Do ◽

M. Gonen ◽

R. Yaeger ◽

M. Weiser ◽

...

Keyword(s):

Rectal Cancer ◽

Neoadjuvant Therapy ◽

Early Onset ◽

Locally Advanced ◽

Advanced Rectal Cancer ◽

A Retrospective Analysis Comparing Outcomes Following Total Neoadjuvant Therapy and Following Neoadjuvant Chemoradiation Therapy in Patients with Locally Advanced Rectal Cancer

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2019.06.2074 ◽

2019 ◽

Vol 105 (1) ◽

pp. E179

Author(s):

S. Zhu ◽

P. Brodin ◽

K. English ◽

N. Ohri ◽

J.W. Chuy ◽

...

Keyword(s):

Rectal Cancer ◽

Neoadjuvant Therapy ◽

Retrospective Analysis ◽

Locally Advanced ◽

Advanced Rectal Cancer ◽

Neoadjuvant Chemoradiation ◽

Chemoradiation Therapy ◽

Neoadjuvant Chemoradiation Therapy ◽

Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial

The Lancet Oncology ◽

10.1016/s1470-2045(15)00004-2 ◽

2015 ◽

Vol 16 (8) ◽

pp. 957-966 ◽

Cited By ~ 257

Author(s):

Julio Garcia-Aguilar ◽

Oliver S Chow ◽

David D Smith ◽

Jorge E Marcet ◽

Peter A Cataldo ◽

...

Keyword(s):

Rectal Cancer ◽

Locally Advanced ◽

Advanced Rectal Cancer ◽

Neoadjuvant Chemoradiation ◽

Phase 2 ◽

Multicentre Phase ◽

Phase 2 Trial

Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer—The New Standard of Care?

JAMA Oncology ◽

10.1001/jamaoncol.2018.0070 ◽

2018 ◽

Vol 4 (6) ◽

pp. e180070 ◽

Cited By ~ 9

Author(s):

Theodore S. Hong ◽

David P. Ryan

Keyword(s):

Rectal Cancer ◽

Neoadjuvant Therapy ◽

Locally Advanced ◽

Standard Of Care ◽

Advanced Rectal Cancer ◽

Cost-Effectiveness Analysis of Total Neoadjuvant Therapy Followed by Radical Resection Versus Conventional Therapy for Locally Advanced Rectal Cancer

Diseases of the Colon & Rectum ◽

10.1097/dcr.0000000000001325 ◽

2019 ◽

Vol 62 (5) ◽

pp. 568-578 ◽

Cited By ~ 2

Author(s):

Moriah E. Wright ◽

Jennifer S. Beaty ◽

Alan G. Thorson ◽

Ruben Rojas ◽

Charles A. Ternent

Keyword(s):

Rectal Cancer ◽

Cost Effectiveness ◽

Neoadjuvant Therapy ◽

Conventional Therapy ◽

Locally Advanced ◽

Radical Resection ◽

Advanced Rectal Cancer ◽

Effectiveness Analysis ◽