B-63 Subacute Cognitive Sequelae of Mild Traumatic Brain Injury on the Cambridge Neuropsychological Test Automated Battery (CANTAB) and Traditional Neuropsychological Tests

2019 ◽  
Vol 34 (6) ◽  
pp. 1009-1010
Author(s):  
J Stenberg ◽  
R Karlsen ◽  
S Saksvik ◽  
G Iverson ◽  
J Karr ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Outcome Measures ◽  
Mild Traumatic Brain Injury ◽  
Neuropsychological Tests ◽  
Neuropsychological Test ◽  
Effect Sizes ◽  
World Health ◽  
Cognitive Test ◽  
Community Controls

Abstract Objective This study examined cognitive functioning at approximately two weeks following mild traumatic brain injury (MTBI) and explored whether tests from the Cambridge Neuropsychological Test Automated Battery (CANTAB) revealed greater differences between patients with MTBI and controls than traditional neuropsychological tests. Method Patients with MTBIs (n = 177) according to the World Health Organization criteria, trauma controls with orthopedic injuries (n = 79), and community controls (n = 81) were assessed with 18 neuropsychological tests an average of 17 days post injury (SD = 3 days). The tests consisted of both traditional, well-established, paper and pencil tests (9 tests, 11 outcome measures) and tests from the CANTAB battery (9 tests, 14 outcome measures). Results Of the 25 outcome measures, the groups only differed significantly on the Coding subtest from the WAIS-IV battery (uncorrected Kruskal-Wallis test: p = 0.025), with lower performance in the MTBI group compared to the community control group (Cliff’s delta = -0.20). Effect sizes of the differences between patients with MTBI and community controls ranged from -0.16 to 0.01 on the CANTAB tests and -0.20 to 0.00 on the traditional tests. Effect sizes of the differences between patients with MTBI and trauma controls ranged from -0.13 to 0.06 on the CANTAB tests and -0.15 to 0.02 on the traditional tests. Conclusions Patients with MTBI did not have significantly lower cognitive test performance than trauma controls or community controls on a large number of tests two weeks after injury. Further, differences between patients with MTBI and controls were similar for the CANTAB battery and traditional tests.

scholarly journals Auditory and Cognitive Behavioral Performance Deficits and Symptom Reporting in Postconcussion Syndrome Following Mild Traumatic Brain Injury

2019 ◽  
Vol 62 (7) ◽  
pp. 2501-2518 ◽  
Author(s):  
Kathy R. Vander Werff ◽  
Brian Rieger
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Function ◽  
Mild Traumatic Brain Injury ◽  
Neuropsychological Tests ◽  
Symptom Reporting ◽  
Cognitive Test ◽  
Postconcussion Symptoms ◽  
Abnormal Performance

Purpose This study examined auditory deficits and symptom reporting in individuals with long-term postconcussion symptoms following a single mild traumatic brain injury (mTBI) compared to age- and gender-matched controls without a history of mTBI. Method Case history interviews, symptom questionnaires, and a battery of central auditory and neuropsychological tests were administered to 2 groups. The mTBI group was a civilian population recruited from a local concussion management program who were seeking rehabilitation for postconcussion-related problems in a postacute period between 3 and 18 months following injury. Symptom validity testing was included to assess the rate of possible insufficient test effort and its influence on scores for all outcome measures. Analyses of group differences in test scores were performed both with and without the participants who showed insufficient test effort. Rates of symptom reporting, correlations among symptoms and behavioral test outcomes, and the relationships between auditory and cognitive test performance were analyzed. Results The mTBI group reported a high rate of auditory symptoms and general postconcussion symptoms. Performance on neuropsychological tests of cognitive function showed some differences in raw scores between groups, but when effort was considered, there were no significant differences in the rate of abnormal performance between groups. In contrast, there were significant differences in both raw scores and the rate of abnormal performance between groups for some auditory tests when only considering participants with sufficient effort. Auditory symptoms were strongly correlated with other general postconcussion symptoms. Conclusions Significant auditory symptoms and evidence of long-term central auditory dysfunction were found in a subset of individuals who had chronic postconcussion symptoms after a single mTBI unrelated to blast trauma. The rate of abnormal performance on auditory behavioral tests exceeded the rate of abnormal performance on tests of cognitive function. Supplemental Material https://doi.org/10.23641/asha.8329955

A-97 Headache before and after Mild Traumatic Brain Injury: Acute-to-Subacute Outcomes in Patients with no Headache, Pre-Existing Headache, and Post-Traumatic Headache

2021 ◽  
Vol 36 (6) ◽  
pp. 1145-1145
Author(s):  
Justin E Karr ◽  
Michael W Williams ◽  
Grant L Iverson ◽  
Sheng-Jean Huang ◽  
Chi-Cheng Yang
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Neuropsychological Tests ◽  
Neuropsychological Test ◽  
Future Research ◽  
Cognitive Symptoms ◽  
Post Injury ◽  
Before And After ◽  
Post Traumatic

Abstract Objective Patients who experience a mild traumatic brain injury (MTBI) may have a headache condition preceding injury, develop a post-traumatic headache after injury, or experience headache neither before nor after injury. This study examined whether MTBI patients with no headache, pre-existing headache, and post-traumatic headache differed in acute-to-subacute outcomes. Method Patients with MTBI were recruited from an outpatient neurosurgery clinic in Taipei, Taiwan after emergency department referral (N = 291; 40.2% men; M = 37.9 ± 13.9 years-old; Mdn = 7 days-since-injury, range = 0–21), completing neuropsychological tests of attention, memory, and verbal fluency and questionnaires evaluating depression, anxiety, and post-concussion symptoms. Participants with no headache (reported neither pre- or post-injury), pre-existing headache (reported pre-injury headache, of whom some reported worsened post-injury headache), and post-traumatic headache (denied pre-injury headache, reported post-injury headache) were compared using non-parametric ANCOVA, controlling for gender and days-since-injury. Results Neuropsychological test performances did not differ between headache groups. Participants with pre-injury headache and post-traumatic headache had greater change in self-reported physical (F = 25.52, p < 0.011, η2 = 0.15) and cognitive symptoms (F = 3.74, p = 0.025, η2 = 0.03) than participants with no headache. Participants with pre-injury headache reported worse post-injury anxiety symptoms than participants with post-traumatic headache (F = 12.02, p < 0.011, η2 = 0.08). Conclusion(s) Participants with pre-injury and post-traumatic headache did not differ in outcome within 21 days of injury but had worse self-reported physical and cognitive symptoms than participants with no headache. Most participants with pre-injury headache experienced worsened headache following MTBI (53.7%). Future research is needed to assess whether more specific headache subtypes are differentially associated with MTBI outcome.

Posttraumatic Stress Disorder Exacerbates Emotional Complaints but not Cognitive Impairments in Individuals Suffering from Postconcussional Disorder after Mild Traumatic Brain Injury

2015 ◽  
Vol 26 (1) ◽  
pp. 35-50 ◽  
Author(s):  
Sara C. Schroeder ◽  
Ronald M. Ruff ◽  
Lutz Jäncke
Keyword(s):  
Traumatic Brain Injury ◽  
Posttraumatic Stress Disorder ◽  
Brain Injury ◽  
Posttraumatic Stress ◽  
Mild Traumatic Brain Injury ◽  
Test Performance ◽  
Stress Disorder ◽  
Negative Impact ◽  
Neuropsychological Test ◽  
Composite Scale

The aim of this study was to examine the effect of posttraumatic stress disorder (PTSD) on (a) neuropsychological test performance and (b) self-reported emotional complaints within individuals suffering from postconcussional disorder (PCD) after a mild traumatic brain injury (MTBI). A two-group comparative research design was employed. Two MTBI samples with and without PTSD were assessed with a neuropsychological test battery and the Ruff Neurobehavioral Inventory (RNBI). On the neurocognitive test performances no significant between group differences were found, but the MTBI group with PTSD endorsed a significantly greater number of emotional complaints, especially in the RNBI subscales of anxiety and depression. The patients with PTSD also endorsed a significantly greater number of premorbid sequelae in the RNBI emotional composite scale as well as the RNBI premorbid subscales of pain, anxiety and abuse. In sum, PTSD has a negative impact on emotional but not cognitive functioning within individuals suffering from PCD after a mild TBI.

Neuropsychological test validity in Veterans presenting with subjective complaints of ‘very severe’ cognitive symptoms following mild traumatic brain injury

Brain Injury ◽  
2016 ◽  
Vol 31 (1) ◽  
pp. 32-38 ◽  
Author(s):  
Robert J. Spencer ◽  
Brigid Waldron-Perrine ◽  
Lauren L. Drag ◽  
Percival H. Pangilinan ◽  
Bradley N. Axelrod ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Neuropsychological Test ◽  
Test Validity ◽  
Cognitive Symptoms ◽  
Subjective Complaints

scholarly journals Examining the Subacute Effects of Mild Traumatic Brain Injury Using a Traditional and Computerized Neuropsychological Test Battery

2021 ◽  
Vol 38 (1) ◽  
pp. 74-85
Author(s):  
Rune Hatlestad Karlsen ◽  
Simen Berg Saksvik ◽  
Jonas Stenberg ◽  
Astri Johansen Lundervold ◽  
Alexander Olsen ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Neuropsychological Test ◽  
Test Battery ◽  
Neuropsychological Test Battery

scholarly journals Improving the translational potential of rodent models to study the behavioral and pathophysiological effects of repetitive mild traumatic brain injury

2018 ◽  
Vol 120 (1) ◽  
pp. 1-3
Author(s):  
Megan E. Huibregtse
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Outcome Measures ◽  
Mild Traumatic Brain Injury ◽  
Chronic Traumatic Encephalopathy ◽  
Rodent Models ◽  
Head Impacts ◽  
Repetitive Head Impacts ◽  
The Impact

Chronic traumatic encephalopathy (CTE) is thought to be caused by repetitive head impacts. Consequently, there is a need to develop rodent models to better understand the behavioral and pathophysiological changes of repetitive mild traumatic brain injury (rmTBI) and to determine the link between rmTBI and CTE. This Neuro Forum article reviews recent rodent rmTBI models, comparing the impact methods and outcome measures in terms of translational potential.

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