The role of quantitative structure - activity relationships (QSAR) in biomolecular discovery

D. A. Winkler

doi:10.1093/bib/3.1.73

The role of quantitative structure - activity relationships (QSAR) in biomolecular discovery

Briefings in Bioinformatics ◽

10.1093/bib/3.1.73 ◽

2002 ◽

Vol 3 (1) ◽

pp. 73-86 ◽

Cited By ~ 82

Author(s):

D. A. Winkler

Keyword(s):

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Antitumor 1-(X-aryl)-3,3-dialkyltriazenes. 2. On the role of correlation analysis in decision making in drug modification. Toxicity quantitative structure-activity relationships of 1-(X-phenyl)-3,3-dialkyltriazenes in mice

Journal of Medicinal Chemistry ◽

10.1021/jm00204a013 ◽

1978 ◽

Vol 21 (6) ◽

pp. 574-577 ◽

Cited By ~ 28

Author(s):

Corwin Hansch ◽

Gerard J. Hatheway ◽

Frank R. Quinn ◽

Nathaniel Greenberg

Keyword(s):

Decision Making ◽

Correlation Analysis ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Drug Modification

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Quantitative structure–activity relationships in prooxidant cytotoxicity of polyphenols: Role of potential of phenoxyl radical/phenol redox couple

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2005.07.002 ◽

2005 ◽

Vol 441 (2) ◽

pp. 182-190 ◽

Cited By ~ 54

Author(s):

Aušra Nemeikaitė-Čėnienė ◽

Aušra Imbrasaitė ◽

Eglė Sergedienė ◽

Narimantas Čėnas

Keyword(s):

Phenoxyl Radical ◽

Redox Couple ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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ChemInform Abstract: ANTITUMOR 1-(X-ARYL)-3,3-DIALKYLTRIAZENES. PART 2. ON THE ROLE OF CORRELATION ANALYSIS IN DECISION MAKING IN DRUG MODIFICATION. TOXICITY QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS OF 1-(X-PHENYL)-3,3-DIALKYLTRIAZENES IN MICE

Chemischer Informationsdienst ◽

10.1002/chin.197848179 ◽

1978 ◽

Vol 9 (48) ◽

Author(s):

C. HANSCH ◽

G. J. HATHEWAY ◽

F. R. QUINN ◽

N. GREENBERG

Keyword(s):

Decision Making ◽

Correlation Analysis ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Drug Modification

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Interspecies quantitative structure–activity relationships (QSARs) for eco-toxicity screening of chemicals: the role of physicochemical properties

SAR and QSAR in Environmental Research ◽

10.1080/1062936x.2015.1104520 ◽

2015 ◽

Vol 26 (10) ◽

pp. 809-830 ◽

Cited By ~ 5

Author(s):

A. Furuhama ◽

K. Hasunuma ◽

Y. Aoki

Keyword(s):

Physicochemical Properties ◽

Toxicity Screening ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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The expanding role of quantitative structure-activity relationships (QSAR) in toxicology

Toxicology Letters ◽

10.1016/0378-4274(95)03356-p ◽

1995 ◽

Vol 79 (1-3) ◽

pp. 45-53 ◽

Cited By ~ 114

Author(s):

Corwin Hansch ◽

David Hoekman ◽

Albert Leo ◽

Litai Zhang ◽

Peng Li

Keyword(s):

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Quantitative Structure–Activity Relationships for Acute Aquatic Toxicity: The Role of Mechanism of Toxic Action in Successful Modeling

Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens ◽

10.1201/9780203010822-13 ◽

2003 ◽

pp. 249-272

Keyword(s):

Aquatic Toxicity ◽

Toxic Action ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Acute Aquatic Toxicity ◽

Quantitative Structure Activity Relationships

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Quantitative Structure-Activity Relationships of Potential Antimalarial Drugs Active Against Chloroquine-Resistant Plasmodium Falciparum

Planta Medica ◽

10.1055/s-2008-1075144 ◽

2008 ◽

Vol 74 (03) ◽

Author(s):

SJ Hocart ◽

H Liu ◽

D De ◽

FM Krogstad ◽

DJ Krogstad

Keyword(s):

Plasmodium Falciparum ◽

Antimalarial Drugs ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Parabolic Quantitative Structure–Activity Relationships and Photodynamic Therapy: Application of a Three-Compartment Model with Clearance to the In Vivo Quantitative Structure–Activity Relationships of a Congeneric Series of Pyropheophorbide Derivatives Used as Photosensitizers for Photodynamic Therapy

Photochemistry and Photobiology ◽

10.1562/0031-8655(1999)070<0781:pqsrap>2.3.co;2 ◽

1999 ◽

Vol 70 (5) ◽

pp. 781 ◽

Cited By ~ 2

Author(s):

W. R. Potter ◽

B. W. Henderson ◽

D. A. Bellnier ◽

R. K. Pandey ◽

L. A. Vaughan ◽

...

Keyword(s):

Photodynamic Therapy ◽

Compartment Model ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Three Compartment Model ◽

Quantitative Structure Activity Relationships

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Binding Affinity of Triphenyl Acrylonitriles to Estrogen Receptors: Quantitative Structure-Activity Relationships

Folia Medica ◽

10.2478/v10153-010-0005-2 ◽

2010 ◽

Vol 52 (3) ◽

Cited By ~ 1

Author(s):

Sorana Bolboacă ◽

Monica Marta ◽

Lorentz Jäntschi

Keyword(s):

Estrogen Receptors ◽

Binding Affinity ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Quantitative Structure-Activity Relationships for Cellular Uptake of Surface-Modified Nanoparticles

Combinatorial Chemistry & High Throughput Screening ◽

10.2174/1386207318666150306105525 ◽

2015 ◽

Vol 18 (4) ◽

pp. 365-375 ◽

Cited By ~ 6

Author(s):

Rong Liu ◽

Robert Rallo ◽

Muhammad Bilal ◽

Yoram Cohen

Keyword(s):

Cellular Uptake ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Surface Modified ◽

Surface Modified Nanoparticles

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