Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis

Brain ◽

10.1093/brain/awq345 ◽

2011 ◽

Vol 134 (2) ◽

pp. 506-517 ◽

Author(s):

Janine Kirby ◽

Ke Ning ◽

Laura Ferraiuolo ◽

Paul R. Heath ◽

Azza Ismail ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Protein Kinase ◽

Motor Neuron ◽

Protein Kinase B ◽

Superoxide Dismutase 1 ◽

Neuron Survival ◽

Motor Neuron Survival ◽

Phosphatase And Tensin Homologue ◽

Lateral Sclerosis

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Familial Amyotrophic Lateral Sclerosis with a Novel G85S Mutation of Superoxide Dismutase 1 Gene: Clinical Features of Lower Motor Neuron Disease

Internal Medicine ◽

10.2169/internalmedicine.49.2720 ◽

2010 ◽

Vol 49 (2) ◽

pp. 183-186 ◽

Author(s):

Takanori Takazawa ◽

Ken Ikeda ◽

Takehisa Hirayama ◽

Kiyokazu Kawabe ◽

Yoshikazu Nakamura ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Motor Neuron ◽

Motor Neuron Disease ◽

Clinical Features ◽

Lower Motor Neuron ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Lower Motor Neuron Disease ◽

Lateral Sclerosis

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The G41D mutation in the superoxide dismutase 1 gene is associated with slow motor neuron progression and mild cognitive impairment in a Chinese family with amyotrophic lateral sclerosis

Journal of Neurology Neurosurgery & Psychiatry ◽

10.1136/jnnp-2015-310545 ◽

2015 ◽

Vol 87 (7) ◽

pp. 788-789 ◽

Author(s):

Qi Niu ◽

Yongxiang Yi ◽

Xueping Sun ◽

Tiannv Li ◽

Bingfeng Zhang ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Motor Neuron ◽

Chinese Family ◽

Superoxide Dismutase 1 ◽

Lateral Sclerosis

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Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: Mechanisms of mitochondriopathy and cell death

The Journal of Comparative Neurology ◽

10.1002/cne.21160 ◽

2006 ◽

Vol 500 (1) ◽

pp. 20-46 ◽

Author(s):

Lee J. Martin ◽

Zhiping Liu ◽

Kevin Chen ◽

Ann C. Price ◽

Yan Pan ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Transgenic Mice ◽

Motor Neuron ◽

Superoxide Dismutase 1 ◽

Motor Neuron Degeneration ◽

Neuron Degeneration ◽

Lateral Sclerosis

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Altered distribution and levels of cathepsinD and cystatins in amyotrophic lateral sclerosis transgenic mice: Possible roles in motor neuron survival

Neuroscience ◽

10.1016/j.neuroscience.2006.07.048 ◽

2006 ◽

Vol 143 (2) ◽

pp. 419-430 ◽

Author(s):

H. Wootz ◽

E. Weber ◽

L. Korhonen ◽

D. Lindholm

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Transgenic Mice ◽

Motor Neuron ◽

Neuron Survival ◽

Motor Neuron Survival ◽

Lateral Sclerosis

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Bisperoxovanadium promotes motor neuron survival in models of amyotrophic lateral sclerosis

The FASEB Journal ◽

10.1096/fasebj.2021.35.s1.03929 ◽

2021 ◽

Vol 35 (S1) ◽

Author(s):

Lydia Tierney ◽

Junmei Wang ◽

Ranjeet Mann ◽

Thomas Lonsway ◽

Chandler Walker

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Motor Neuron ◽

Neuron Survival ◽

Motor Neuron Survival ◽

Lateral Sclerosis

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Concurrent Administration of Neu2000 and Lithium Produces Marked Improvement of Motor Neuron Survival, Motor Function, and Mortality in a Mouse Model of Amyotrophic Lateral Sclerosis

Molecular Pharmacology ◽

10.1124/mol.106.030676 ◽

2006 ◽

Vol 71 (4) ◽

pp. 965-975 ◽

Author(s):

Jin Hee Shin ◽

Sung Ig Cho ◽

Hyang Ran Lim ◽

Jae Keun Lee ◽

Young Ae Lee ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Mouse Model ◽

Motor Neuron ◽

Motor Function ◽

Marked Improvement ◽

Concurrent Administration ◽

Neuron Survival ◽

Motor Neuron Survival ◽

Lateral Sclerosis

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Astrocytes in amyotrophic lateral sclerosis: direct effects on motor neuron survival

Journal of Biological Physics ◽

10.1007/s10867-009-9141-4 ◽

2009 ◽

Vol 35 (4) ◽

pp. 337-346 ◽

Author(s):

K. A. Staats ◽

L. Van Den Bosch

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Motor Neuron ◽

Direct Effects ◽

Neuron Survival ◽

Motor Neuron Survival ◽

Lateral Sclerosis

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Calcitonin gene-related peptide expression levels predict motor neuron vulnerability in the superoxide dismutase 1-G93A mouse model of amyotrophic lateral sclerosis

Neurobiology of Disease ◽

10.1016/j.nbd.2011.09.011 ◽

2012 ◽

Vol 45 (1) ◽

pp. 547-554 ◽

Author(s):

Cornelia Ringer ◽

Eberhard Weihe ◽

Burkhard Schütz

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Mouse Model ◽

Motor Neuron ◽

Superoxide Dismutase 1 ◽

Expression Levels ◽

Related Peptide ◽

Calcitonin Gene ◽

Peptide Expression ◽

Lateral Sclerosis

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MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis

Autophagy ◽

10.4161/auto.27710 ◽

2014 ◽

Vol 10 (4) ◽

pp. 588-602 ◽

Author(s):

Xiaojie Zhang ◽

Sheng Chen ◽

Lin Song ◽

Yu Tang ◽

Yufei Shen ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Mouse Model ◽

Motor Neuron ◽

Autophagic Flux ◽

Neuron Survival ◽

Motor Neuron Survival ◽

Lateral Sclerosis

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Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2002.01211.x ◽

2002 ◽

Vol 83 (5) ◽

pp. 1030-1042 ◽

Author(s):

Makoto Urushitani ◽

Junko Kurisu ◽

Kayoko Tsukita ◽

Ryosuke Takahashi

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Motor Neuron ◽

Familial Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase 1 ◽

Neuron Death ◽

Proteasomal Inhibition ◽

Motor Neuron Death ◽

Lateral Sclerosis

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