scholarly journals Analysis of Severe Adverse Events Reported Among Patients Receiving Isoniazid-Rifapentine Treatment for Latent Mycobacterium tuberculosis Infection—United States, 2012–2016

2020 ◽  
Author(s):  
Kristine M Schmit ◽  
Jonathan M Wortham ◽  
Christine S Ho ◽  
Krista M Powell
Keyword(s):  
United States ◽  
Mycobacterium Tuberculosis ◽  
Adverse Events ◽  
Elevated Serum ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
Severe Adverse Events ◽  
Serum Aminotransferases

Abstract We analyzed data from 2012 to 2016 for patients who were hospitalized or who died after ≥1 dose of isoniazid-rifapentine for treatment of latent Mycobacterium tuberculosis infection. No patients died; 15 were hospitalized. Nine patients experienced hypotension, and 5 had elevated serum aminotransferases, reinforcing the need for vigilant monitoring during treatment.

Kikuchi–Fujimoto's Disease in a Pediatric Patient with Mycobacterium tuberculosis Infection

2017 ◽  
Vol 14 (05) ◽  
pp. 260-263 ◽  
Author(s):  
Muayad Alali ◽  
Jefree J. Schulte ◽  
Barbara A. Hendrickson
Keyword(s):  
United States ◽  
Mycobacterium Tuberculosis ◽  
Lupus Erythematosus ◽  
Clinical Symptoms ◽  
Case Reports ◽  
Young Male ◽  
The United States ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
Laboratory Findings

AbstractKikuchi–Fujimoto's disease (KFD), alternatively termed histiocytic necrotizing lymphadenitis, was first described in 1972. KFD is rare in children, with most of the cases occurring between the ages of 20 and 30 years with a female-to-male ratio of 4:1. The etiology is unknown, although infectious and autoimmune mechanisms have been proposed. KFD manifests with a spectrum of nonspecific clinical symptoms and laboratory findings. KFD is without a definitive diagnostic test and is a diagnosis of exclusion, which must be differentiated from other disease processes with associated lymphadenopathy. Significant overlap in both clinical presentation and histological features with other diseases, such as non-Hodgkin lymphoma, systemic lupus erythematosus, and active tuberculosis (TB), presents challenges in diagnosis. A small number of case reports have been published describing the coexistence of KFD and active TB. Most reported cases occur in TB endemic areas. In the largest analysis of KFD, TB infection was concurrent in 2% of cases. Most of the cases occurred in adult patients. To our knowledge, there have been no pediatric cases of KFD with concurrent TB infection reported in the United States. This study describes a case of KFD with concurrent Mycobacterium tuberculosis infection in a young male from the United States.

scholarly journals Assessment of the QuantiFERON-TB Gold In-Tube test for the detection of Mycobacterium tuberculosis infection in United States Navy recruits

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0177752 ◽  
Author(s):  
Jason M. Lempp ◽  
Margan J. Zajdowicz ◽  
Arlene L. Hankinson ◽  
Sean R. Toney ◽  
Lisa W. Keep ◽  
...  
Keyword(s):  
United States ◽  
Mycobacterium Tuberculosis ◽  
United States Navy ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
Tube Test

scholarly journals Time Since Infection and Risks of Future Disease for Individuals with Mycobacterium tuberculosis Infection in the United States

Epidemiology ◽  
2020 ◽  
Vol 32 (1) ◽  
pp. 70-78
Author(s):  
Nicolas A. Menzies ◽  
Nicole Swartwood ◽  
Christian Testa ◽  
Yelena Malyuta ◽  
Andrew N. Hill ◽  
...  
Keyword(s):  
United States ◽  
Mycobacterium Tuberculosis ◽  
The United States ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection
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