Liquid-chromatographic determination of aminoglutethimide in plasma.
Keyword(s):
Abstract A simple, rapid "high-performance" liquid-chromatographic procedure is presented for the determination of aminoglutethimide in plasma. After precipitation of the protein with acetonitrile, an aliquot of the supernate is injected directly onto a radially compressed, reversed-phase column. The aminoglutethimide is isocratically eluted with a mobile phase of acetonitrile/water/tert-butyl ammonium phosphate. The method is both accurate and precise and has been in routine use in our laboratory for more than 12 months.
1983 ◽
Vol 29
(10)
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pp. 1840-1842
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1986 ◽
Vol 382
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pp. 207-213
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1986 ◽
Vol 355
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pp. 340-344
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1985 ◽
Vol 345
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pp. 157-161
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1996 ◽
Vol 34
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pp. 389-393
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2001 ◽
Vol 24
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pp. 2315-2324
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