Erythromycin-Induced QT Prolongation and Polymorphic Ventricular Tachycardia (Torsades de Pointes): Case Report and Review

1994 ◽  
Vol 18 (6) ◽  
pp. 995-998 ◽  
Author(s):  
M. W. Brandriss ◽  
W. S. Richardson ◽  
S. S. Barold
Keyword(s):  
Ventricular Tachycardia ◽  
Case Report ◽  
Torsades De Pointes ◽  
Qt Prolongation ◽  
Polymorphic Ventricular Tachycardia

scholarly journals Severe Torsades de Pointes with acquired QT prolongation

2016 ◽  
Vol 8 (8) ◽  
pp. 775-776 ◽  
Author(s):  
Akhil Narang ◽  
Cevher Ozcan
Keyword(s):  
Ventricular Tachycardia ◽  
Successful Treatment ◽  
Torsades De Pointes ◽  
Severe Case ◽  
Qt Prolongation ◽  
Polymorphic Ventricular Tachycardia ◽  
Electrolyte Disturbances ◽  
Electrolyte Replacement

Torsades de pointes (TdP) is a fatal polymorphic ventricular tachycardia in association with congenital or acquired QT prolongation. Concomitant electrolyte disturbances and drugs potentiate the development of TdP. We describe a severe case of refractory TdP in the setting of methadone, cocaine, hypokalemia and hypomagnesemia. The successful treatment was achieved with the administration of magnesium, isoproterenol, and electrolyte replacement.

Life-Threatening Ventricular Arrhythmia (Torsades de Pointes) after Haloperidol Overdose

1991 ◽  
Vol 10 (1) ◽  
pp. 59-62 ◽  
Author(s):  
R.A. Henderson ◽  
S. Lane ◽  
J.A. Henry
Keyword(s):  
Ventricular Tachycardia ◽  
Literature Review ◽  
Ventricular Arrhythmia ◽  
Torsades De Pointes ◽  
Qt Prolongation ◽  
Life Threatening ◽  
Overdrive Pacing

A 48-year-old woman developed QT prolongation and episodes of life-threatening ventricular tachycardia (torsades de pointes) after intentional overdose of haloperidol and orphenadrine. The arrhythmia did not respond to conventional anti-arrhythmic therapy but was suppressed by atrial overdrive pacing. A literature review identified haloperidol as the most likely cause of the torsades de pointes.

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