High leptin and resistin expression in chronic heart failure: adverse outcome in patients with dilated and inflammatory cardiomyopathy

2012 ◽  
Vol 14 (11) ◽  
pp. 1265-1275 ◽  
Author(s):  
Peter Bobbert ◽  
Alexander Jenke ◽  
Thomas Bobbert ◽  
Uwe Kühl ◽  
Ursula Rauch ◽  
...  
2016 ◽  
Vol 19 (4) ◽  
pp. 502-511 ◽  
Author(s):  
Franz Duca ◽  
Caroline Zotter-Tufaro ◽  
Andreas A. Kammerlander ◽  
Adelheid Panzenböck ◽  
Stefan Aschauer ◽  
...  

2021 ◽  
Vol 10 (3) ◽  
pp. 65-71
Author(s):  
S. L. Glizer ◽  
O. A. Shtegman ◽  
M. M. Petrova

Abstract. Chronic heart failure is one of the main contributors to the Global Burden of Cardiovascular Diseases. Despite advances in modern treatment, acute decompensated heart failure (ADHF) incidence is high. Moreover, patients admitted for ADHF encounter renal impairment, which is another predictor of adverse outcome. There are number of biomarkers that allow clinicians to assess the prognosis of the disease in the early stages. The article presents an overview of contemporary biomarkers (utilizing multimarker approach), and identifies the most significant biological markers for evaluating ADHF and worsening renal function.


2013 ◽  
Vol 16 (1) ◽  
pp. 68-75 ◽  
Author(s):  
Ståle H. Nymo ◽  
Johannes Hulthe ◽  
Thor Ueland ◽  
John McMurray ◽  
John Wikstrand ◽  
...  

2015 ◽  
Vol 1 (2) ◽  
pp. 90 ◽  
Author(s):  
Pierpaolo Pellicori ◽  
Kuldeep Kaur ◽  
Andrew L Clark ◽  
◽  
◽  
...  

Congestion, or fluid overload, is a classic clinical feature of patients presenting with heart failure patients, and its presence is associated with adverse outcome. However, congestion is not always clinically evident, and more objective measures of congestion than simple clinical examination may be helpful. Although diuretics are the mainstay of treatment for congestion, no randomised trials have shown the effects of diuretics on mortality in chronic heart failure patients. Furthermore, appropriate titration of diuretics in this population is unclear. Research is required to determine whether a robust method of detecting — and then treating — subclinical congestion improves outcomes.


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