scholarly journals SELECTION IN FINITE POPULATIONS. I. THE PROBABILITY OF FIXATION AND RATE OF RESPONSE USING TRANSITION MATRIX ITERATION

Genetics ◽  
1970 ◽  
Vol 65 (1) ◽  
pp. 157-173
Author(s):  
Philip W Hedrick
Keyword(s):  
Transition Matrix ◽  
Finite Populations ◽  
Matrix Iteration ◽  
Probability Of Fixation ◽  
Rate Of Response

scholarly journals The Response to Artificial Selection Due to Autosomal Genes of Large Effect III. The Effects of Linkage on the Rate of Advance and Approach to Fixation in Finite Populations

1966 ◽  
Vol 19 (1) ◽  
pp. 131 ◽  
Author(s):  
BDH Latter
Keyword(s):  
Linkage Disequilibrium ◽  
Artificial Selection ◽  
Half Life ◽  
Initial Rate ◽  
Genetic Model ◽  
Selection Process ◽  
Total Response ◽  
Finite Populations ◽  
The Mean ◽  
Rate Of Response

The effects of linkage on the total response to artificial selection in finite populations have been discussed in the second paper of this series, making use of a simple genetic model involving two identical loci of additive effect. In the present paper the following related parameters are discussed: (1) the initial rate of response; (2) the half-life and 0�95 life of the selection process; (3) the number of generations to 50 and 95% fixation; (4) the mean coefficient of linkage disequilibrium; and (5) the coefficient of joint segregation.

DETERMINATION OF THE TRANSITION MATRIX WITH N-COUPLED CHANNELS

1989 ◽  
Vol 50 (C1) ◽  
pp. C1-119-C1-125 ◽  
Author(s):  
S. BOUGOUFFA ◽  
X. C. CAO
Keyword(s):  
Transition Matrix ◽  
Coupled Channels

Effects of Observer Variation on Performance in Probabilistic Diagnosis of Jaundice

1981 ◽  
Vol 20 (03) ◽  
pp. 163-168 ◽  
Author(s):  
G. Llndberg
Keyword(s):  
Physical Examination ◽  
System Performance ◽  
Transition Matrix ◽  
Bayes Theorem ◽  
Observer Variation ◽  
Kappa Statistics ◽  
Diagnostic Categories ◽  
Number Of Patients ◽  
Probability Transition Matrix ◽  
Probabilistic Diagnosis

A system for probabilistic diagnosis of jaundice has been used for studying the effects of taking into account the unreliability of diagnostic data caused by observer variation. Fourteen features from history and physical examination were studied. Bayes’ theorem was used for calculating the probabilities of a patient’s belonging to each of four diagnostic categories.The construction sample consisted of 61 patients. An equal number of patients were tested in the evaluation sample. Observer variation on the fourteen features had been assessed in two previous studies. The use of kappa-statistics for measuring observer variation allowed the construction of a probability transition matrix for each feature. Diagnostic probabilities could then be calculated with and without the inclusion of weights for observer variation. Tests of system performance revealed that discriminatory power remained unchanged. However, the predictions rendered by the variation-weighted system were diffident. It is concluded that taking observer variation into account may weaken the sharpness of probabilistic diagnosis but it may also help to explain the value of probabilistic diagnosis in future applications.

Temperature control in a chemical reactor through variable area of the heat transfer surface. Experimental verification

1982 ◽  
Vol 47 (2) ◽  
pp. 446-453
Author(s):  
Josef Horák ◽  
František Jiráček ◽  
Libuše Ježová
Keyword(s):  
Batch Reactor ◽  
Exothermic Reaction ◽  
Chemical Reactor ◽  
Open Loop ◽  
Heat Transfer Surface ◽  
Laboratory Reactor ◽  
Hysteresis Control ◽  
Relay With Hysteresis ◽  
Rate Of Response ◽  
The Ideal

A possibility has been tested in the paper of the feed back control of temperature of the reaction mixture in a batch reactor with an exothermic reaction through the variable area of the cooling surface. The measurement were carried out in a laboratory reactor with a retractable cooler which was being immersed into the reaction mixture. The speed of motion of the cooler was sufficiently high permitting the process of immersion to be regarded as practically instantaneous. The aim of the control was to stabilize the set point temperature of the reaction mixture by a two-point controler. In dependence on the rate of response of the system to a change of the section variable either the ideal relay or the relay with hysteresis control algorithmus were used. The results of measurements showed that with the aid of a retractable cooler the temperature could be controlled safely even in those cases, in which the control by the variable flow rate of the coolant was unfeasible. The verification was carried out in the open-loop instable operating point of the reactor.

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