scholarly journals EDUCATIONAL OUTREACH IN ALZHEIMER’S DISEASE AMONG OLDER AFRICAN AMERICANS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S862-S862
Author(s):  
Ashley R Shaw ◽  
Briana Bright ◽  
Jaime Perales Puchalt ◽  
Eric Vidoni ◽  
Gabriela Amparan ◽  
...  

Abstract Alzheimer’s disease (AD) is a growing public health problem that continues to disproportionally impact African Americans. African Americans are twice as likely to be afflicted with AD compared to non-Latino Whites. However, continued lack of inclusion of African Americans in clinical research trials may reduce the generalizability of future treatments. We investigated how culturally tailored prevention education impacted knowledge, attitudes, and beliefs of AD among older African Americans. We also assessed how culturally tailored prevention education impacted participation in clinical research trials among older African Americans. Researchers delivered “Aging with Grace,” a culturally tailored dementia program to community and faith-based organizations. Demographic information, knowledge of AD, and beliefs of clinical research trials were collected using pre- and post-surveys. In addition, information from community members interested in enrolling in a clinical research study was acquired. A total of 66 community members attended “Aging with Grace” from March to August 2019. 32% of participants perceived an increase in AD knowledge. Most participants (89.1%) believed that more African Americans should participate in research and 29 (44%) expressed interest in enrolling in clinical trials (observational – 73.2%, prevention – 68.2%, treatment – 24.4%). Most participants (93.1%) rated the presentation highly informative and 78% reported that the presentation was very applicable to their daily life. Overall knowledge of AD and interest in participating clinical trials improved with culturally tailored education. Future research should explore ways of enhancing knowledge and participation to enhance inclusion in prevention and treatment trials.

2020 ◽  
Author(s):  
Ashley R. Shaw ◽  
Jaime Perales-Puchalt ◽  
Briana Bright ◽  
Todd Moore ◽  
Melissa Robinson ◽  
...  

African Americans are disproportionally affected by Alzheimers disease and related dementia (ADRD) and are two times more likely to develop ADRD compared to their White counterparts. Despite the higher prevalence of ADRD among older African Americans, less than 5% of African Americans participate in clinical research trials. Purpose: The purpose of the study was to explore how a culturally tailored community-based recruitment method impacts 1) enrollment in ADRD research studies among older African Americans in the Midwest and 2) ADRD knowledge and perception of clinical trials. Methods: Using a community-engaged research approach, we collaborated with two predominately African American serving organizations to support the content development and the delivery of Aging With Grace (AWG); a culturally tailored dementia educational curriculum. Results: A total of five AWG presentations were presented to 66 attendees. Most attendees (67%) expressed interest in participating in clinical trials after attending AWG, 18.2% of attendees enrolled in an observational clinical research study and 4.5% enrolled in a lifestyle prevention clinical trial within 5 months of the AWG presentation. Attendees (32%) also perceived an increase in ADRD knowledge from attending AWG and 89.1% believed more African Americans should participate in research. Conclusion: The study has demonstrated the effectiveness of a community-based recruitment method using AWG to enhance knowledge, clinical trial interest, and recruitment into observational and lifestyle ADRD clinical trials among older African Americans. Future studies should assess long-term efficacy of this AWG community-based recruitment method among other underrepresented minority populations.


2013 ◽  
Vol 36 (3) ◽  
pp. 597-606 ◽  
Author(s):  
Angela L. Jefferson ◽  
Susan Lambe ◽  
Raymond R. Romano ◽  
Dandan Liu ◽  
Fareesa Islam ◽  
...  

2006 ◽  
Vol 14 (7S_Part_20) ◽  
pp. P1077-P1078
Author(s):  
Grace Byfield ◽  
Takiyah Starks ◽  
Michael L. Cuccaro ◽  
Larry D. Adams ◽  
Patrice L. Whitehead ◽  
...  

2012 ◽  
Vol 8 (4S_Part_10) ◽  
pp. P377-P377 ◽  
Author(s):  
Rosalyn Lang ◽  
Goldie Byrd ◽  
Takiyah Starks ◽  
Dora Som-Pimpong ◽  
Ruth Phillips ◽  
...  

2016 ◽  
Vol 6 (10) ◽  
pp. 627
Author(s):  
Carol Dillon ◽  
Patricio Pérez Leguizamon ◽  
Silvina Heisecke ◽  
Diego M. Castro ◽  
Jorge Lopez Camelo ◽  
...  

Background: The use of biomarkers in basic and clinical research as well as in clinical practice has become so common that their presence as primary endpoints in clinical trials is now accepted. A biomarker refers to a broad subcategory of medical signs. The aims of this article are to consider the of use biomarkers in Mild stages of Alzheimer’s disease (AD) in research and clinical settings, in addition to defining their utility in clinical practice relating this with nutritional and lifestyle factors as possible treatment. Methods: We searched MEDLINE, PubMed, and AgeLine databases using different keywords.Conclusions: A summary of the utility of biomarkers in AD and nutritional and lifestyle factors used as treatment in mild stages are described.Key words: Biomarkers, Alzheimer’s disease, Dementia, Utility, Clinical practice, Nutritional


2015 ◽  
Vol 31 (4) ◽  
pp. 361-367 ◽  
Author(s):  
J. Christina Howell ◽  
Oretunlewa Soyinka ◽  
Monica Parker ◽  
Thomas L. Jarrett ◽  
David L. Roberts ◽  
...  

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