Instability of simple sequence repeats in a mammalian cell line

1994 ◽  
Vol 3 (2) ◽  
pp. 253-256 ◽  
Author(s):  
Rosann A. Farber ◽  
Thomas D. Petes ◽  
Margaret Dominska ◽  
Sarah S. Hudgens ◽  
R.Michael Liskay
Keyword(s):  
Cell Line ◽  
Mammalian Cell ◽  
Simple Sequence Repeats ◽  
Mammalian Cell Line ◽  
Simple Sequence

Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor

1992 ◽  
Vol 225 (4) ◽  
pp. 331-337 ◽  
Author(s):  
Pierre Sokoloff ◽  
Marc Andrieux ◽  
Roger Besançon ◽  
Catherine Pilon ◽  
Marie-Pascale Martres ◽  
...  
Keyword(s):  
Cell Line ◽  
Mammalian Cell ◽  
D2 Receptor ◽  
Dopamine D3 Receptor ◽  
D3 Receptor ◽  
Mammalian Cell Line ◽  
Dopamine D3

Radiosensitization of a Mammalian Cell Line with 5-Bromodeoxyuridine

1962 ◽  
Vol 17 (4) ◽  
pp. 479 ◽  
Author(s):  
N. Delihas ◽  
M. A. Rich ◽  
M. L. Eidinoff
Keyword(s):  
Cell Line ◽  
Mammalian Cell ◽  
Mammalian Cell Line

scholarly journals Construction and Modelling of an Inducible Positive Feedback Loop Stably Integrated in a Mammalian Cell-Line

2011 ◽  
Vol 7 (6) ◽  
pp. e1002074 ◽  
Author(s):  
Velia Siciliano ◽  
Filippo Menolascina ◽  
Lucia Marucci ◽  
Chiara Fracassi ◽  
Immacolata Garzilli ◽  
...  
Keyword(s):  
Cell Line ◽  
Mammalian Cell ◽  
Positive Feedback ◽  
Feedback Loop ◽  
Mammalian Cell Line ◽  
Positive Feedback Loop

The use of ‘Omics technology to rationally improve industrial mammalian cell line performance

2015 ◽  
Vol 113 (1) ◽  
pp. 26-38 ◽  
Author(s):  
Amanda M. Lewis ◽  
Nicholas R. Abu-Absi ◽  
Michael C. Borys ◽  
Zheng Jian Li
Keyword(s):  
Cell Line ◽  
Mammalian Cell ◽  
Mammalian Cell Line ◽  
Omics Technology

scholarly journals Expression of Recombinant Non Structural 1 Protein of Dengue Virus Serotype-2 in Mammalian Cell Line

2019 ◽  
Vol 13 (1) ◽  
pp. 36-42 ◽  
Author(s):  
FITHRIYAH SJATHA ◽  
◽  
OKTIVIA CHANDRA MUSTIKA ◽  
ANGKY BUDIANTI ◽  
TJAHJANI MIRAWATI SUDIRO ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Cell Line ◽  
Mammalian Cell ◽  
Mammalian Cell Line ◽  
Virus Serotype ◽  
Dengue Virus Serotype 2

Biological Studies of a Baculovirus in a Mammalian Cell Line

Intervirology ◽  
1980 ◽  
Vol 13 (6) ◽  
pp. 331-341 ◽  
Author(s):  
Arthur H. Mclntosh ◽  
Rebecca Shamy
Keyword(s):  
Cell Line ◽  
Mammalian Cell ◽  
Mammalian Cell Line ◽  
Biological Studies

A mammalian cell line deficient in activity of the DNA repair enzyme 5-hydroxymethyluracil-DNA glycosylase is resistant to the toxic effects of the thymidine analog 5-hydroxymethyl-2'-deoxyuridine

1992 ◽  
Vol 12 (12) ◽  
pp. 5536-5540
Author(s):  
R J Boorstein ◽  
L N Chiu ◽  
G W Teebor
Keyword(s):  
Dna Repair ◽  
Cell Line ◽  
Mammalian Cell ◽  
Dna Glycosylase ◽  
Mammalian Cell Line ◽  
Repair Enzyme ◽  
Thymidine Analog ◽  
Large Numbers ◽  
Mechanism Of Toxicity ◽  
Base Excision

We isolated a mutant mammalian cell line lacking activity for the DNA repair enzyme 5-hydroxymethyluracil-DNA glycosylase (HmUra-DNA glycosylase). The mutant was isolated through its resistance to the thymidine analog 5-hydroxymethyl-2'-deoxyuridine (HmdUrd). The mutant incorporates HmdUrd into DNA to the same extent as the parent line but, lacking the repair enzyme, does not remove it. The phenotype of the mutant demonstrates that the toxicity of HmdUrd does not result from substitution of thymine in DNA by HmUra but rather from the removal via base excision of large numbers of HmUra residues in DNA. This finding elucidates a novel mechanism of toxicity for a xenobiotic nucleoside. Furthermore, the isolation of this line supports our hypothesis that the enzymatic repairability of HmUra derives not from its formation opposite adenine via the oxidation of thymine, but rather from its formation opposite guanine as a product of the oxidation and subsequent deamination of 5-methylcytosine.

scholarly journals Nav1.3 Sodium Channels: Rapid Repriming and Slow Closed-State Inactivation Display Quantitative Differences after Expression in a Mammalian Cell Line and in Spinal Sensory Neurons

2001 ◽  
Vol 21 (16) ◽  
pp. 5952-5961 ◽  
Author(s):  
Theodore R. Cummins ◽  
Fabio Aglieco ◽  
Mathurkrisnan Renganathan ◽  
Raimund I. Herzog ◽  
Sulayman D. Dib-Hajj ◽  
...  
Keyword(s):  
Cell Line ◽  
Sodium Channels ◽  
Mammalian Cell ◽  
Sensory Neurons ◽  
Mammalian Cell Line ◽  
Closed State

Avipoxvirus multiplication in a mammalian cell line

2005 ◽  
Vol 109 (1) ◽  
pp. 39-49 ◽  
Author(s):  
Simon Chioma Weli ◽  
Øivind Nilssen ◽  
Terje Traavik
Keyword(s):  
Cell Line ◽  
Mammalian Cell ◽  
Mammalian Cell Line
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