scholarly journals Do cycle disturbances explain the age-related decline of female fertility? Cycle characteristics of women aged over 40 years compared with a reference population of young women

2003 ◽  
Vol 18 (3) ◽  
pp. 495-501 ◽  
Author(s):  
P.v. Zonneveld
Keyword(s):  
Young Women ◽  
Reference Population ◽  
Female Fertility ◽  
Fertility Cycle ◽  
Age Related ◽  
Over 40 Years

The archaeology of osteoporosis

2001 ◽  
Vol 4 (2) ◽  
pp. 263-269 ◽  
Author(s):  
Gordon Turner-Walker ◽  
Unni Syversen ◽  
Simon Mays
Keyword(s):  
Bone Loss ◽  
Femoral Neck ◽  
Young Women ◽  
Rapid Decline ◽  
Mineral Density ◽  
Medieval Women ◽  
Age Related ◽  
Pregnancy And Lactation ◽  
Post Menopausal ◽  
The Uk

The application of medical scanning technologies to archaeological skeletons provides novel insights into the history and potential causes of osteoporosis. The present study investigated bone mineral density (BMD) in medieval skeletons from England and Norway. Comparisons between the two adult populations found no statistically significant differences. This compares with a modern fracture incidence for the femoral neck in women from Norway that is almost three times that in the UK. The pattern of age-related bone loss in medieval men was similar to that seen in men today. In contrast, the pattern in medieval women differed from that of modern young women. On average, medieval women experienced a decrease in BMD at the femoral neck of approximately 23 per cent between the ages of 22 and 35. These losses were partially recovered by age 45, after which BMD values show a decline consistent with post-menopausal bone loss in modern western women. A possible explanation of the rapid decline in BMD in young medieval women is bone loss in connection with pregnancy and lactation in circumstances of insufficient nutrition.

INFLUENCE OF THE AGE ON BAROREFLEX SYNCHRONIZATION OF ARTERIAL PRESSURE AND HEART RATE DURING THE PASSIVE STANDING TEST

2021 ◽  
Vol 55 (1) ◽  
pp. 46-50
Author(s):  
Е.А. Orlova ◽  
◽  
О.S. Tarasova ◽  
V.D. Son'kin ◽  
А.S. Borovik ◽  
...  
Keyword(s):  
Heart Rate ◽  
Phase Synchronization ◽  
Tilt Test ◽  
Breathing Rate ◽  
Age Related ◽  
Head Up Tilt ◽  
Wave Range ◽  
Standing Test ◽  
Head Up Tilt Test ◽  
Over 40 Years

Age-related changes in phase synchronization of spontaneous blood pressure (BP) and heart rate (HR) fluctuations within the baroreflex wave range (about 0.1 Hz) were studied in 66 subjects aged 20 to 52 years. Measurements performed during the head-up tilt test included continuous BP monitoring using the volume-compensation method, ECG recording for ensuing HR calculation, and breathing rate recording. The phase synchronization index (PSI) was used for evaluation of BP-HR coupling. In supine position, phase synchronization in the subjects over 40 years was higher as compared with their counterparts at the age of 20 to 24 years. Along with that, less pronounced PSI increase in people over 40 in response to the tilt test suggests a decline of the baroreflex activity with aging.

Reference intervals for plasma lipoperoxides: age-, sex-, and specimen-related variations.

1987 ◽  
Vol 33 (12) ◽  
pp. 2289-2291 ◽  
Author(s):  
J A Knight ◽  
S E Smith ◽  
V E Kinder ◽  
H B Anstall
Keyword(s):  
Older Women ◽  
Young Women ◽  
Blood Donors ◽  
Sodium Citrate ◽  
Older Men ◽  
Reference Intervals ◽  
Female Adult ◽  
Experimental Animals ◽  
Age Related ◽  
Younger Men

Abstract We measured lipoperoxides, as malondialdehyde (MDA), by liquid chromatography in plasma from 230 male and 148 female adult blood donors, to establish reliable reference values and to compare possible sex-, age-, and specimen-related differences. Our studies show that mean have higher MDA concentrations in plasma than do women (P less than 0.05), older men have higher values than younger men (P less than 0.05), and older women have higher values than young women (P less than 0.001). These age-related results support earlier studies in experimental animals that lipid peroxidation increases with increasing age. In addition, plasma from liquid EDTA-anti-coagulated blood has significantly lower MDA concentrations than does serum or plasma from blood treated with lithium heparin, sodium citrate, or CPDA-1 (P less than 0.001).

Age-related reference intervals for bone turnover markers from an Australian reference population

Bone ◽  
2013 ◽  
Vol 55 (2) ◽  
pp. 271-276 ◽  
Author(s):  
N. Jenkins ◽  
M. Black ◽  
E. Paul ◽  
J.A. Pasco ◽  
M.A. Kotowicz ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Reference Population ◽  
Reference Intervals ◽  
Age Related ◽  
Turnover Markers

“The Curse” - - Vicissitudes and Variations of the Female Fertility Cycle

1966 ◽  
Vol 7 (4) ◽  
pp. 242-247 ◽  
Author(s):  
David S. Janowsky ◽  
Roderic Gorney ◽  
Bret Kelley
Keyword(s):  
Female Fertility ◽  
Fertility Cycle

scholarly journals Age-related features of walking with cognitive tasks

2019 ◽  
pp. 68-76
Author(s):  
V. M. Moroz ◽  
M. V. Yoltukhivskyy ◽  
O. V. Vlasenko ◽  
G. S. Moskovko ◽  
O. V. Bogomaz ◽  
...  
Keyword(s):  
Young Women ◽  
Cognitive Task ◽  
Step Length ◽  
Human Walking ◽  
Cognitive Tasks ◽  
Temporal Parameters ◽  
Age Related ◽  
Spatial Parameters ◽  
Spatio Temporal ◽  
Support Time

Human walking is considered as a complex cognitive act. The research purpose is an analysis of age-related features of spatio-temporal parameters of human walking and directions of their changes at walking with dual (cognitive) tasks. The walking spatio-temporal indexes were studied in 608 individuals of both sexes aged 12-43 years by GAITRite® (CIR Systems Inc.,Clifton, NJ) under normal walking at individually comfortable velocity and under additional cognitive tasks: 1) sequentially pronounce aloud any known animals; 2) starting from a number 100, subtract 7 and pronounce the result aloud. The statistical processing of the got results was carried out in the licensed software “STATISTICA 5.5”. At performing the first, simpler, task, the spatial parameters had no significant changes in all age groups. Most of the temporal parameters changed: cycle time, swing time, single support time, and double support time increased. Therefore, equilibrium maintaining at walking with naming animals is realized with a longer overall support period, reducing the walking cadence and velocity. The constant width of the support base and the angle of the feet turn indicate that the magnitudes of the functional support base and angle of the feet turn at normal walking is sufficient to maintain posture and balance at walking with simultaneous performance of the cognitive task, as well as more rigid mechanisms of regulation of these two parameters. The walking temporal parameters are more labile than spatial parameters. With age, the percentage of the integral index of walking quality (FAP) decreases especially in females: in girls by 15.3 %, in young women by 14.4 %, in middle-aged women by 7.4 %. At performing the second, more complex, arithmetic task, in young men and young girls support base, toe-in-out, step length difference had no significant changes only. The mean velocity, cadence, step length, stride length, step extremity ratio decreased. The count of steps, all temporal parameters, and stance percentage increased. FAP declined critically by 30.4 % in young men and 33.4 % in young women, indicating a decrease in balance and body stability under walking with cognitive task and increasing the risk of falls. Therefore, a significant reduction in FAP can be used as a diagnostic criterion in neurological practice.

scholarly journals Sex and age differences in the association between sympathetic outflow and central elastic artery wall thickness in humans

2019 ◽  
Vol 317 (3) ◽  
pp. H552-H560 ◽  
Author(s):  
Seth W. Holwerda ◽  
Rachel E. Luehrs ◽  
Lyndsey E. DuBose ◽  
Rumbidzai Majee ◽  
Gary L. Pierce
Keyword(s):  
Carotid Artery ◽  
Age Differences ◽  
Young Women ◽  
Wall Thickness ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Sympathetic Outflow ◽  
Artery Wall ◽  
Carotid Imt ◽  
Age Related

Aging is characterized by increased wall thickness of the central elastic arteries (i.e., aorta and carotid arteries), although the mechanisms involved are unclear. Evidence suggests that age-related increases in muscle sympathetic nerve activity (MSNA) may be a contributing factor. However, studies in humans have been lacking. Therefore, we tested the hypothesis that age-related increases in MSNA would be independently associated with carotid artery intima-media thickness (IMT) but not in young women given the reduced influence of MSNA on the vasculature in this group. In 93 young and middle-age/older (MA/O) adults (19–73 yr, 41 women), we performed assessments of MSNA (microneurography) and common carotid IMT and lumen diameter (ultrasonography). Multiple regression that included MSNA and other cardiovascular disease risk factors indicated that MSNA ( P = 0.002) and 24-h systolic blood pressure (BP) ( P = 0.024) were independent determinants of carotid IMT-to-lumen ratio (model R2 = 0.38, P < 0.001). However, when examining only young women (<45 yr), no correlation was observed between MSNA and carotid IMT-to-lumen ratio ( R = −0.01, P = 0.963). MSNA was significantly correlated with IMT-to-lumen ratio while controlling for 24-h systolic BP among young men ( R = 0.49, P < 0.001) and MA/O women ( R = 0.59, P = 0.022). However, among MA/O men, controlling for 24-h systolic BP attenuated the association between MSNA and carotid IMT-to-lumen ratio ( R = 0.50, P = 0.115). Significant age differences in IMT-to-lumen ratio between young and MA/O men ( P = 0.047) and young and MA/O women ( P = 0.023) were removed when adjusting for MSNA (men: P = 0.970; women: P = 0.152). These findings demonstrate an association between higher sympathetic outflow and carotid artery wall thickness with a particular exception to young women. NEW & NOTEWORTHY Increased wall thickness of the large elastic arteries serves as a graded marker for cardiovascular disease risk and progression of atherosclerosis. Findings from the present study establish an independent association between higher sympathetic outflow and carotid artery wall thickness in adults with an exception to young women and extend findings from animal models that demonstrate hypertrophy of vascular smooth muscle following chronic sympathetic-adrenergic stimulation.

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