Ensuring High and Equitable COVID-19 Vaccine Uptake Among Patients With IBD

Inflammatory Bowel Diseases ◽

10.1093/ibd/izab114 ◽

2021 ◽

Author(s):

Freddy Caldera ◽

Sophie Balzora ◽

Mary S Hayney ◽

Francis A Farraye ◽

Raymond K Cross

Keyword(s):

Inflammatory Bowel Disease ◽

Bowel Disease ◽

Vaccine Uptake ◽

High Uptake ◽

Safety And Efficacy ◽

Inflammatory Bowel ◽

Vaccination Completion

Abstract The recent emergency use authorization of a third COVID-19 vaccine means that most patients with inflammatory bowel disease (IBD) will soon be eligible to be vaccinated. Gastroenterology clinicians should be prepared to address patients’ concerns regarding safety and efficacy of vaccines. They should also strongly recommend that all their patients be vaccinated with a COVID-19 vaccine. Additionally, they should be prepared to educate patients about logistics that will result in successful vaccination completion. All these measures will be crucial to ensure high uptake among their patients with IBD.

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Assessment of the safety and efficacy of biological monotherapy versus dual therapy with immunosuppressants for the treatment of inflammatory bowel disease.

Inflammatory Bowel Diseases ◽

10.1093/ibd/17.supplement1.s65a ◽

2011 ◽

Vol 17 (suppl_1) ◽

pp. S65-S65

Author(s):

C Wheat ◽

S Lynema ◽

C Ko ◽

C Cullinan ◽

S Etter ◽

...

Keyword(s):

Inflammatory Bowel Disease ◽

Bowel Disease ◽

Dual Therapy ◽

Safety And Efficacy ◽

Inflammatory Bowel

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Safety and Efficacy of Bariatric Surgery in Inflammatory Bowel Disease Patients: a Systematic Review and Meta-analysis

Obesity Surgery ◽

10.1007/s11695-020-04729-4 ◽

2020 ◽

Vol 30 (10) ◽

pp. 3872-3883 ◽

Cited By ~ 1

Author(s):

Rajat Garg ◽

Babu P. Mohan ◽

Suresh Ponnada ◽

Amandeep Singh ◽

Ali Aminian ◽

...

Keyword(s):

Systematic Review ◽

Bariatric Surgery ◽

Inflammatory Bowel Disease ◽

Bowel Disease ◽

Meta Analysis ◽

Safety And Efficacy ◽

Inflammatory Bowel

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Safety and Efficacy of Intravenous Iron Sucrose for Iron-Deficiency Anemia in Children and Adolescents With Inflammatory Bowel Disease

Global Pediatric Health ◽

10.1177/2333794x19870981 ◽

2019 ◽

Vol 6 ◽

pp. 2333794X1987098

Author(s):

Ramy Sabe ◽

Anant Vatsayan ◽

Amr Mahran ◽

Ali S. Khalili ◽

Sanjay Ahuja ◽

...

Keyword(s):

Inflammatory Bowel Disease ◽

Iron Deficiency ◽

Iron Deficiency Anemia ◽

Bowel Disease ◽

Intravenous Iron ◽

Iron Sucrose ◽

Deficiency Anemia ◽

Safety And Efficacy ◽

Normal Ranges ◽

Inflammatory Bowel

Background. Anemia is common in inflammatory bowel disease (IBD). Oral iron is widely used but efficacy can be reduced by poor compliance and insufficient absorption. Intravenous iron is safe and effective in adults but is not well studied in children. Purpose. To assess safety and efficacy of intravenous iron sucrose (IVIS) in children with IBD. Methods. We reviewed medical records of IBD patients <22 years of age who received IVIS at our institution between 2009 and 2014. Anemia was defined as hemoglobin (Hgb) level below normal for age and gender and iron-deficiency anemia as serum iron studies and red cell mean corpuscular volume below normal ranges. Each IVIS infusion was evaluated for safety. Efficacy was defined as ≥2 g/dL increase in Hgb ≤12 weeks from IVIS initiation. Results. We identified 88 patients (Crohn’s disease, n = 52; ulcerative colitis, n = 33; IBD-unclassified, n = 3) who underwent 329 IVIS infusions over 121 courses. No patient developed anaphylaxis. Six patients developed minor adverse reactions. Of the 121 IVIS courses, 80 were included in the efficacy evaluation. There was a significant rise in Hgb (mean 9.1 ±1.4 to 11.9 ± 1.8 g/dL; P < .0001, paired t test). Overall, 58.7% (47/80 courses) resulted in goal Hgb increase. Conclusions. IVIS is safe and effective in treating iron-deficiency anemia in pediatric IBD. There were only minor adverse events, and the observed rise in Hgb was clinically significant, with the majority achieving goal Hgb.

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