scholarly journals Safety and efficacy of minimalist approach in transfemoral transcatheter aortic valve replacement: insights from the Optimized transCathEter vAlvular interventioN–Transcatheter Aortic Valve Implantation (OCEAN-TAVI) registry†

2017 ◽  
Vol 26 (3) ◽  
pp. 420-424 ◽  
Author(s):  
Soh Hosoba ◽  
Masanori Yamamoto ◽  
Kayoko Shioda ◽  
Mitsuru Sago ◽  
Yutaka Koyama ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Transcatheter Aortic Valve Implantation ◽  
Transcatheter Aortic Valve Replacement ◽  
Safety And Efficacy ◽  
Transcatheter Aortic Valve ◽  
Minimalist Approach ◽  
Aortic Valve Implantation ◽  
Valve Implantation

The TAVI: Transcatheter Aortic Valve Implantation

2020 ◽  
pp. 49-57
Author(s):  
Giovanni Esposito ◽  
Anna Franzone
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Transcatheter Aortic Valve Implantation ◽  
Transcatheter Aortic Valve Replacement ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
Valve Implantation

L’impianto transcatetere di valvola aortica (Transcatheter Aortic Valve Replacement, TAVI) è una procedura di cardiologia interventistica, introdotta nel 2002, che prevede il posizionamento e l’impianto di una protesi biologica a livello dell’annulus aortico mediante accesso percutaneo, prevalentemente transfemorale. Dopo le prime esperienze cliniche, riservate a pazienti senza altre opzioni terapeutiche, la TAVI si è affermata come alternativa all’intervento chirurgico tradizionale di sostituzione valvolare grazie ad una serie di studi randomizzati che ne hanno dimostrato l’efficacia e la sicurezza in pazienti appartenenti a tutto lo spettro del rischio operatorio (da estremo a basso). L’utilizzo della TAVI è in continua crescita, a livello mondiale, e si assiste ad una progressiva espansione delle sue indicazioni cliniche (stenosi di valvola bicuspide, insufficienza aortica severa). Il presente articolo ha lo scopo di riassumere i recenti progressi nell’ambito del trattamento transcatetere della stenosi valvolare aortica, descrivere le caratteristiche della procedura e analizzare i risultati degli studi che ne hanno favorito la diffusione nella pratica clinica.

Transcatheter Aortic Valve Implantation in Patients With Very High Risk for Conventional Aortic Valve Replacement

2009 ◽  
Vol 88 (5) ◽  
pp. 1468-1474 ◽  
Author(s):  
Matthias Thielmann ◽  
Daniel Wendt ◽  
Holger Eggebrecht ◽  
Philipp Kahlert ◽  
Parwis Massoudy ◽  
...  
Keyword(s):  
High Risk ◽  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Transcatheter Aortic Valve Implantation ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
Valve Implantation ◽  
Very High

scholarly journals Bias estimation in study design: a meta-epidemiological analysis of transcatheter versus surgical aortic valve replacement

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Saerom Youn ◽  
Shannon Avery Wong ◽  
Caitlin Chrystoja ◽  
George Tomlinson ◽  
Harindra C. Wijeysundera ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Transcatheter Aortic Valve Implantation ◽  
Treatment Effects ◽  
Surgical Aortic Valve Replacement ◽  
High Quality ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
Valve Implantation

Abstract Background Paucity of RCTs of non-drug technologies lead to widespread dependence on non-randomized studies. Relationship between nonrandomized study design attributes and biased estimates of treatment effects are poorly understood. Our purpose was to estimate the bias associated with specific nonrandomized study attributes among studies comparing transcatheter aortic valve implantation with surgical aortic valve replacement for the treatment of severe aortic stenosis. Results We included 6 RCTs and 87 nonrandomized studies. Surgical risk scores were similar for comparison groups in RCTs, but were higher for patients having transcatheter aortic valve implantation in nonrandomized studies. Nonrandomized studies underestimated the benefit of transcatheter aortic valve implantation compared with RCTs. For example, nonrandomized studies without adjustment estimated a higher risk of postoperative mortality for transcatheter aortic valve implantation compared with surgical aortic valve replacement (OR 1.43 [95% CI 1.26 to 1.62]) than high quality RCTs (OR 0.78 [95% CI 0.54 to 1.11). Nonrandomized studies using propensity score matching (OR 1.13 [95% CI 0.85 to 1.52]) and regression modelling (OR 0.68 [95% CI 0.57 to 0.81]) to adjust results estimated treatment effects closer to high quality RCTs. Nonrandomized studies describing losses to follow-up estimated treatment effects that were significantly closer to high quality RCT than nonrandomized studies that did not. Conclusion Studies with different attributes produce different estimates of treatment effects. Study design attributes related to the completeness of follow-up may explain biased treatment estimates in nonrandomized studies, as in the case of aortic valve replacement where high-risk patients were preferentially selected for the newer (transcatheter) procedure.

scholarly journals Drivers of healthcare costs associated with the episode of care for surgical aortic valve replacement versus transcatheter aortic valve implantation

Open Heart ◽  
2016 ◽  
Vol 3 (2) ◽  
pp. e000468 ◽  
Author(s):  
Harindra C Wijeysundera ◽  
Lindsay Li ◽  
Vevien Braga ◽  
Nandhaa Pazhaniappan ◽  
Anar M Pardhan ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Transcatheter Aortic Valve Implantation ◽  
Healthcare Costs ◽  
Surgical Aortic Valve Replacement ◽  
Transcatheter Aortic Valve ◽  
Episode Of Care ◽  
Aortic Valve Implantation ◽  
Valve Implantation

scholarly journals Transcatheter aortic valve implantation compared with surgical aortic valve replacement in patients with anaemia

2017 ◽  
Vol 73 (1) ◽  
pp. 50-59 ◽  
Author(s):  
Paola D’Errigo ◽  
Fausto Biancari ◽  
Stefano Rosato ◽  
Corrado Tamburino ◽  
Marco Ranucci ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Transcatheter Aortic Valve Implantation ◽  
Surgical Aortic Valve Replacement ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
Valve Implantation
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