scholarly journals Staging of Schizophrenia With the Use of PANSS: An International Multi-Center Study

2019 ◽  
Vol 22 (11) ◽  
pp. 681-697 ◽  
Author(s):  
Konstantinos N Fountoulakis ◽  
Elena Dragioti ◽  
Antonis T Theofilidis ◽  
Tobias Wikilund ◽  
Xenofon Atmatzidis ◽  
...  

Abstract Introduction A specific clinically relevant staging model for schizophrenia has not yet been developed. The aim of the current study was to evaluate the factor structure of the PANSS and develop such a staging method. Methods Twenty-nine centers from 25 countries contributed 2358 patients aged 37.21 ± 11.87 years with schizophrenia. Analysis of covariance, Exploratory Factor Analysis, Discriminant Function Analysis, and inspection of resultant plots were performed. Results Exploratory Factor Analysis returned 5 factors explaining 59% of the variance (positive, negative, excitement/hostility, depression/anxiety, and neurocognition). The staging model included 4 main stages with substages that were predominantly characterized by a single domain of symptoms (stage 1: positive; stages 2a and 2b: excitement/hostility; stage 3a and 3b: depression/anxiety; stage 4a and 4b: neurocognition). There were no differences between sexes. The Discriminant Function Analysis developed an algorithm that correctly classified >85% of patients. Discussion This study elaborates a 5-factor solution and a clinical staging method for patients with schizophrenia. It is the largest study to address these issues among patients who are more likely to remain affiliated with mental health services for prolonged periods of time.

1970 ◽  
Vol 117 (538) ◽  
pp. 241-250 ◽  
Author(s):  
H. J. Eysenck

As is well known, there has been a good deal of discussion about the unitary or binary nature of depression. Mapother (1926) and Lewis (1934) made a strong case for the unitary view on clinical grounds, Curran (1937) concurring. Kendell (1968) has reviewed the history of this argument; it is marred by confusion which has persisted through recent attempts to use statistical techniques of factor analysis and discriminant function analysis in an effort to find a more objective and empirical solution. It is the purpose of this brief note to draw attention to this confusion, to show how it has affected arguments of both adherents and opponents of the binary position, and to argue that the data are in fact in sufficient agreement to make possible a valid answer to both problems. It is suggested that the apparent disagreement between workers such as those of the Newcastle group (Kiloh and Garside, 1963; Carney, Roth and Garside, 1965) and the London (Maudsley) group (Kendell, 1968) is in fact quite irrelevant and is based on a misunderstanding of the statistical properties of factors, a misunderstanding apparently introduced in one of the first studies of this kind to be concerned with the problem of the classification of depressive illness, that by Hamilton and White (1959).


2012 ◽  
Vol 15 (3) ◽  
pp. 1043-1054 ◽  
Author(s):  
Francisco Pablo Holgado Tello ◽  
Leandro Navas Martínez ◽  
Irene Jover Mira

Based on academic goal theory, we compared the goals of visually impaired and sighted students. Participants included 171 students affiliated with ONCE (the National Spanish Organization for the Blind) and 163 sighted students, ranging from 8 to 27 years of age, who responded to the Spanish adaptation (González, Torregrosa, & Navas, 2002) of the goals questionnaire created by Hayamizu, Ito, and Yohiazaki (1989) and Hayamizu and Weiner (1991). Factor analysis indicated that goals varied among these students and that new ones arose in this study; furthermore, the model remained invariable regardless of students' status (visually impaired versus sighted). Cluster analysis revealed three distinct profiles in terms of academic goals, while discriminant function analysis suggested these profiles vary as a function of students' status (visually impaired versus sighted). It seems that visually impaired students hold more learning-oriented academic goals.


1986 ◽  
Vol 16 (4) ◽  
pp. 325-334 ◽  
Author(s):  
Mary Limbacher ◽  
George Domino

The Suicide Opinion Questionnaire (SOQ) was administered to a sample ( N=738) of undergraduate volunteers, and responses were analyzed comparing attempters ( N = 35), contemplators ( N = 131) and nonattempters ( N = 483). A factor analysis indicated seven significant factors accounting for 24.2 percent of the total variance. A discriminant function analysis, using the seven factors, yielded two significant functions that discriminated respondents on the basis of sex and prior suicide history. The results are considered in the context of three issues (acceptability, lethality, and mental illness) important to the dynamics of suicide, and in terms of Goffman's theory of deviance.


1980 ◽  
Vol 19 (04) ◽  
pp. 205-209
Author(s):  
L. A. Abbott ◽  
J. B. Mitton

Data taken from the blood of 262 patients diagnosed for malabsorption, elective cholecystectomy, acute cholecystitis, infectious hepatitis, liver cirrhosis, or chronic renal disease were analyzed with three numerical taxonomy (NT) methods : cluster analysis, principal components analysis, and discriminant function analysis. Principal components analysis revealed discrete clusters of patients suffering from chronic renal disease, liver cirrhosis, and infectious hepatitis, which could be displayed by NT clustering as well as by plotting, but other disease groups were poorly defined. Sharper resolution of the same disease groups was attained by discriminant function analysis.


Diversity ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 18
Author(s):  
Long Kim Pham ◽  
Bang Van Tran ◽  
Quy Tan Le ◽  
Trung Thanh Nguyen ◽  
Christian C. Voigt

This study is the first step towards more systematic monitoring of urban bat fauna in Vietnam and other Southeast Asian countries by collecting bat echolocation call parameters in Ho Chi Minh and Tra Vinh cities. We captured urban bats and then recorded echolocation calls after releasing in a tent. Additional bat’s echolocation calls from the free-flying bats were recorded at the site where we captured bat. We used the obtained echolocation call parameters for a discriminant function analysis to test the accuracy of classifying these species based on their echolocation call parameters. Data from this pilot work revealed a low level of diversity for the studied bat assemblages. Additionally, the discriminant function analysis successfully classified bats to four bat species with an accuracy of >87.4%. On average, species assignments were correct for all calls from Taphozous melanopogon (100% success rate), for 70% of calls from Pipistrellus javanicus, for 80.8% of calls from Myotis hasseltii and 67.3% of calls from Scotophilus kuhlii. Our study comprises the first quantitative description of echolocation call parameters for urban bats of Vietnam. The success in classifying urban bats based on their echolocation call parameters provides a promising baseline for monitoring the effect of urbanization on bat assemblages in Vietnam and potentially also other Southeast Asian countries.


2012 ◽  
Vol 60 (4) ◽  
pp. 387-404 ◽  
Author(s):  
Mohamed Agha ◽  
Ray E. Ferrell ◽  
George F. Hart

1986 ◽  
Vol 23 (6) ◽  
pp. 804-812 ◽  
Author(s):  
A. B. Beaudoin ◽  
R. H. King

The magnetite composition from three sets of samples of Mazama, St. Helens set Y, and Bridge River tephras from Jasper and Banff national parks are used to test whether discriminant function analysis can unambiguously distinguish these tephras. The multivariate method is found to be very sensitive to the change in reference samples. St. Helens set Y tephra is clearly distinguished. However, discrimination between Mazama and Bridge River tephras is less distinct. A set of unknown tephras from the Sunwapta Pass area was used to test the classification schemes. Unknown tephras are assigned to different tephra types depending on which reference tephra set is used in the discriminant function analysis.


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