scholarly journals Antimicrobial susceptibility patterns and macrolide resistance genes of viridans group streptococci from blood cultures in Korea

2004 ◽  
Vol 53 (6) ◽  
pp. 1095-1097 ◽  
Author(s):  
Y. Uh
Keyword(s):  
Resistance Genes ◽  
Antimicrobial Susceptibility ◽  
Blood Cultures ◽  
Macrolide Resistance ◽  
Viridans Group Streptococci ◽  
Susceptibility Patterns

scholarly journals In Vitro Activity of Telithromycin against Viridans Group Streptococci and Streptococcus bovis Isolated from Blood: Antimicrobial Susceptibility Patterns in Different Groups of Species

2005 ◽  
Vol 49 (2) ◽  
pp. 820-823 ◽  
Author(s):  
Iciar Rodríguez-Avial ◽  
Carmen Rodríguez-Avial ◽  
Esther Culebras ◽  
Juan J. Picazo
Keyword(s):  
Antimicrobial Susceptibility ◽  
Macrolide Resistance ◽  
Vitro Activity ◽  
Streptococcus Bovis ◽  
In Vitro Activity ◽  
Viridans Group Streptococci ◽  
Susceptibility Patterns

ABSTRACT The in vitro activities of penicillin, erythromycin, clindamycin, and telithromycin were determined against 155 viridans group streptococci (VGS) and 18 Streptococcus bovis blood isolates. Heterogeneity in the susceptibility patterns and macrolide resistance phenotypes and genotypes in the different groups of VGS was detected. We found seven telithromycin-resistant S. bovis isolates all harboring the erm(B) gene.

scholarly journals Antimicrobial Susceptibility Patterns and Macrolide Resistance Genes of β-Hemolytic Streptococci in Korea

2004 ◽  
Vol 48 (7) ◽  
pp. 2716-2718 ◽  
Author(s):  
Young Uh ◽  
In Ho Jang ◽  
Gyu Yel Hwang ◽  
Mi Kyung Lee ◽  
Kap Jun Yoon ◽  
...  
Keyword(s):  
Resistance Genes ◽  
Antimicrobial Susceptibility ◽  
Macrolide Resistance ◽  
Resistance Phenotype ◽  
Susceptibility Patterns

ABSTRACT In 540 beta-hemolytic streptococci, the rates of resistance to tetracycline, chloramphenicol, erythromycin, and clindamycin were 80.0, 22.8, 20.2, and 19.1%, respectively. Of the erythromycin-resistant isolates, 63.3% had the constitutive macrolide-lincosamide-streptogramin B (MLSB) resistance phenotype, 23.9% had the M phenotype, and 12.8% had the inducible MLSB resistance phenotype. The constitutive MLSB resistance phenotype with the erm(B) gene was dominant in Korea.

scholarly journals Sepsis in cancer patients residing in Zimbabwe: Spectrum of bacterial and fungal aetiologies and their antimicrobial susceptibility patterns.

2019 ◽  
Author(s):  
FRANK CHINOWAITA ◽  
Wendy Chaka ◽  
Tinashe K Nyazika ◽  
Tendai C Maboreke ◽  
Inam Chitsike ◽  
...  
Keyword(s):  
Blood Culture ◽  
Cancer Patients ◽  
Antimicrobial Susceptibility ◽  
Methicillin Resistance ◽  
Antimicrobial Treatment ◽  
Blood Cultures ◽  
Gram Negative ◽  
E Coli ◽  
Patients With Cancer ◽  
Susceptibility Patterns

Abstract Introduction: Cancer and sepsis comorbidity is a major public health problem in most parts of the world including Zimbabwe. The microbial aetiologies of sepsis and their antibiograms vary with time and locations. Knowledge on local microbial aetiologies of sepsis and their susceptibility patterns is critical in guiding empirical antimicrobial treatment choices. Methods: This was a descriptive cross sectional study which determined the microbial aetiologies of sepsis from blood cultures of paediatric and adult cancer patients obtained between July 2016 and June 2017. The TDR-X120 blood culture system and TDR 300B auto identification machine were used for incubation of blood culture bottles and identification plus antimicrobial susceptibility testing, respectively. Results: A total of 142 participants were enrolled; 50 (35.2%) had positive blood cultures with 56.0% gram positive, 42.0% gram negative bacteria and 2.0% yeast isolates. Most common isolates were Coagulase Negative Staphylococcus (CoNS) (22.0%), Escherichia coli (16.0%), Klebsiella pneumoniae (14.0%), Enterococcus faecalis (14.0%) and Staphylococcus aureus (8.0%) in all cancer patients. These isolates were similar in both haematological and solid cancers. Amikacin and meropenem showed 85.7% and 95.2% activity respectively against all gram negative isolates while vancomycin and linezolid were effective against 96.2% and 100.0% of all gram positive isolates respectively. Ten (66.7%) isolates of E. coli and K. pneumoniae were extended spectrum β-lactamase (ESBL) positive and the same proportion was observed on methicillin resistance among Staphylococcus species. Conclusions: The major microbial aetiologies of sepsis among patients with cancer in Zimbabwe were CoNS, E. coli, K. pneumoniae, E. faecalis and S. aureus. Most isolates were resistant to commonly used empirical antibiotics and there was high level of ESBL and methicillin resistance carriage. A nationwide survey on microbial aetiologies of sepsis and their susceptibility patterns would assist in the guidance of effective sepsis empiric antimicrobial treatment among patients with cancer.

Antimicrobial susceptibility and macrolide resistance genes in Streptococcus pyogenes collected in Austria and Hungary

2004 ◽  
Vol 24 (3) ◽  
pp. 290-293 ◽  
Author(s):  
Rainer Gattringer ◽  
Robert Sauermann ◽  
Heimo Lagler ◽  
Karin Stich ◽  
Astrid Buxbaum ◽  
...  
Keyword(s):  
Streptococcus Pyogenes ◽  
Resistance Genes ◽  
Antimicrobial Susceptibility ◽  
Macrolide Resistance

Macrolide resistance phenotypes of commensal viridans group streptococci and Gemella spp. and PCR detection of resistance genes

2004 ◽  
Vol 23 (6) ◽  
pp. 582-589 ◽  
Author(s):  
P Cerdá Zolezzi ◽  
M.C Rubio Calvo ◽  
L Millán ◽  
P Goñi ◽  
M Canales ◽  
...  
Keyword(s):  
Resistance Genes ◽  
Pcr Detection ◽  
Macrolide Resistance ◽  
Viridans Group Streptococci

scholarly journals Sepsis in cancer patients residing in Zimbabwe: Spectrum of bacterial and fungal aetiologies and their antimicrobial susceptibility patterns.

2019 ◽  
Author(s):  
FRANK CHINOWAITA ◽  
Wendy Chaka ◽  
Tinashe K Nyazika ◽  
Tendai C Maboreke ◽  
Emmanuel Tizauone ◽  
...  
Keyword(s):  
Blood Culture ◽  
Cancer Patients ◽  
Antimicrobial Susceptibility ◽  
Antimicrobial Treatment ◽  
Blood Cultures ◽  
Gram Positive ◽  
Gram Negative ◽  
E Coli ◽  
Patients With Cancer ◽  
Susceptibility Patterns

Abstract Introduction: Cancer and sepsis comorbidity is a major public health problem in most parts of the world including Zimbabwe. The microbial aetiologies of sepsis and their antibiograms vary with time and locations. Knowledge on local microbial aetiologies of sepsis and their susceptibility patterns is critical in guiding empirical antimicrobial treatment choices. Methods: This was a descriptive cross sectional study which determined the microbial aetiologies of sepsis from blood cultures of paediatric and adult cancer patients obtained between July 2016 and June 2017. The TDR-X120 blood culture system and TDR 300B auto identification machine were used for incubation of blood culture bottles and identification plus antimicrobial susceptibility testing, respectively. Clinical and laboratory standards institute (CLSI) standard breakpoints were used to interpret the antimicrobial susceptibility results. Results: A total of 142 participants were enrolled; 50 (35.2%) had positive blood cultures with 56.0% Gram positive, 42.0% Gram negative bacteria and 2.0% yeast isolates. Most common isolates were coagulase negative Staphylococcus spp. (CoNS) (22.0%), Escherichia coli (16.0%), Klebsiella pneumoniae (14.0%), Enterococcus faecalis (14.0%) and Staphylococcus aureus (8.0%) in all cancer patients. These isolates were similar in both haematological and solid cancers. Gram negative isolates exhibited high resistance to gentamicin (61.9%) and ceftriaxone (71.4%) which are the empiric antimicrobial agents used in our setting. Amikacin and meropenem showed 85.7% and 95.2% activity respectively against all Gram negative isolates while vancomycin and linezolid were effective against 96.2% and 100.0% of all Gram positive isolates respectively. Ten (66.7%) isolates of E. coli and K. pneumoniae were extended spectrum β-lactamase (ESBL) positive. Among Staphylococcus species it was also observed that 10/15 (66.7%) of the isolates were methicillin resistan t. Conclusions : The major microbial aetiologies of sepsis among patients with cancer in Zimbabwe were CoNS, E. coli , K. pneumoniae , E. faecalis and S. aureus . Most isolates were resistant to commonly used empirical antibiotics and there was high level of ESBL and methicillin resistance carriage. A nationwide survey on microbial aetiologies of sepsis and their susceptibility patterns would assist in the guidance of effective sepsis empiric antimicrobial treatment among patients with cancer.

scholarly journals Microorganisms isolated from blood cultures and the change of their antimicrobial susceptibility patterns in the last five years

2019 ◽  
Vol 76 (3) ◽  
pp. 231-242
Author(s):  
Tuba Müderris ◽  
Süreyya Gül Yurtsever ◽  
Nurten Baran ◽  
Rahim Özdemir ◽  
Hakan Er ◽  
...  
Keyword(s):  
Antimicrobial Susceptibility ◽  
Blood Cultures ◽  
Susceptibility Patterns
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