Quantitative Determination of Chlorobutanol in Milk by Gas-Liquid Chromatography

1972 ◽  
Vol 55 (5) ◽  
pp. 948-950
Author(s):  
John E Wiskerchen ◽  
Joseph Weishaar
Keyword(s):  
Liquid Chromatography ◽  
Quantitative Determination ◽  
Electron Capture ◽  
Steam Distillation ◽  
Collaborative Study ◽  
Electron Capture Detection ◽  
Gas Liquid Chromatography

Abstract A method is described for the quantitative determination of chlorobutanol in milk by gas-liquid chromatography. The cleanup includes isolation of chlorobutanol from milk by steam distillation and extraction with ether. The chlorobutanol is quantitatively determined on a column of 5% Igepal 880 on Gas-Chrom Q with electron capture detection. Recoveries were 87–101% for milk fortified at 0.01–10 ppm levels. Collaborative study is recommended after an intralaboratory study is completed.

Collaborative Study of the Quantitative Determination of Fusel Oil and Ethyl Acetate by Gas-Liquid Chromatography

1968 ◽  
Vol 51 (4) ◽  
pp. 915-921
Author(s):  
Richard L Brunelle
Keyword(s):  
Liquid Chromatography ◽  
Quantitative Determination ◽  
Ethyl Acetate ◽  
Simultaneous Determination ◽  
Collaborative Study ◽  
Gas Liquid Chromatography ◽  
Fusel Oil ◽  
Preliminary Work ◽  
Standard Deviations

Abstract Thirteen chemists representing twelve laboratories participated in a collaborative study for the quantitative determination of ethyl acetate and fusel oil by GLC. The results on four samples containing various amounts of ethyl acetate and fusel oil were compared with the official AOAC procedures. For all samples, the standard deviations were lower with GLC. Collaborators preferred the GLC procedure because the simultaneous determination of ethyl acetate and n-propyl, iso-butyl, and isoamyl alcohols is possible. Results from preliminary work performed on the quantitative determination of acetaldehyde by GLC were encouraging. It is recommended that the proposed GLC procedure for the quantitative determination of ethyl acetate and fusel oil be adopted as official, first action, and that work be continvied on the determination of acetaldehyde by GLC.

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