KDM5D-mediated H3K4 demethylation is required for sexually dimorphic gene expression in mouse embryonic fibroblasts

2018 ◽  
Vol 165 (4) ◽  
pp. 335-342 ◽  
Author(s):  
Hayase Mizukami ◽  
Jun-Dal Kim ◽  
Saori Tabara ◽  
Weizhe Lu ◽  
Chulwon Kwon ◽  
...  
Keyword(s):  
Gene Expression ◽  
Sexually Dimorphic ◽  
Mouse Embryonic Fibroblasts ◽  
Embryonic Fibroblasts ◽  
Dimorphic Gene Expression

scholarly journals Regulation of c-Fos Gene Expression by NF-κB: A p65 Homodimer Binding Site in Mouse Embryonic Fibroblasts but Not Human HEK293 Cells

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e84062 ◽  
Author(s):  
Yu-Cheng Tu ◽  
Duen-Yi Huang ◽  
Shine-Gwo Shiah ◽  
Jang-Shiun Wang ◽  
Wan-Wan Lin
Keyword(s):  
Gene Expression ◽  
Binding Site ◽  
Hek293 Cells ◽  
Mouse Embryonic Fibroblasts ◽  
Embryonic Fibroblasts

scholarly journals Sexually dimorphic gene expression and transcriptome evolution provide mixed evidence for a fast-Z effect in Heliconius

2019 ◽  
Vol 32 (3) ◽  
pp. 194-204 ◽  
Author(s):  
Ana Pinharanda ◽  
Marjolaine Rousselle ◽  
Simon H. Martin ◽  
Joe J. Hanly ◽  
John W. Davey ◽  
...  
Keyword(s):  
Gene Expression ◽  
Sexually Dimorphic ◽  
Dimorphic Gene Expression

scholarly journals Enrichment of Cxcl12 promoter with TET2: A possible link between promoter demethylation and enhanced gene expression in the absence of PARP-1

2019 ◽  
Vol 71 (3) ◽  
pp. 455-462
Author(s):  
Anja Tolic ◽  
Jovana Rajic ◽  
Marija Djordjevic ◽  
Milos Djordjevic ◽  
Svetlana Dinic ◽  
...  
Keyword(s):  
Gene Expression ◽  
Technological Development ◽  
Cpg Islands ◽  
Gene Induction ◽  
Dna Hypomethylation ◽  
Mouse Embryonic Fibroblasts ◽  
Embryonic Fibroblasts ◽  
Cxcl12 Expression ◽  
Knock Out ◽  
Parp 1

Previously, we described the link between C-X-C motif chemokine 12 (Cxcl12) gene induction and DNA hypomethylation in the absence of poly(ADP-ribose) polymerase 1 (PARP-1). We have now firmly established that demethylation is the primary cause of gene induction on the basis of Cxcl12 gene upregulation upon treatment with the demethylating agent 5-azacytidine (5-aza). Since the demethylation state of Cxcl12 is favored by PARP-1 absence, we investigated the presence of ten-eleven translocation (TET) proteins on the Cxcl12 promoter in order to corroborate the relationship between the demethylation process and increased gene expression that occurs in the absence of PARP-1. Analysis was performed on the promoter region within CpG islands of Cxcl12 from control mouse embryonic fibroblasts (NIH3T3) and PARP-1 knock-out mouse embryonic fibroblasts (PARP1-/-). The lack of PARP-1 increased the abundance of TET2 on the Cxcl12 promoter, suggesting that TET-mediated demethylation provoked by the absence of PARP-1 could account for the observed increased expression of this chemokine. Deciphering the regulation of DNA (de)methylation factors that control Cxcl12 expression may provide an additional therapeutic approach in pharmacological interventions where gene switching on or off based on targeted stimulation or inhibition is necessary. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 173020]

scholarly journals Sexually dimorphic gene expression in the chick brain before gonadal differentiation

2009 ◽  
Vol 88 (5) ◽  
pp. 1003-1015 ◽  
Author(s):  
S.I. Lee ◽  
W.K. Lee ◽  
J.H. Shin ◽  
B.K. Han ◽  
S. Moon ◽  
...  
Keyword(s):  
Gene Expression ◽  
Sexually Dimorphic ◽  
Gonadal Differentiation ◽  
Chick Brain ◽  
Dimorphic Gene Expression

scholarly journals Variable sexually dimorphic gene expression in laboratory strains of Drosophila melanogaster

BMC Genomics ◽  
2007 ◽  
Vol 8 (1) ◽  
pp. 454 ◽  
Author(s):  
Dean A Baker ◽  
Lisa A Meadows ◽  
Jing Wang ◽  
Julian AT Dow ◽  
Steven Russell
Keyword(s):  
Gene Expression ◽  
Drosophila Melanogaster ◽  
Sexually Dimorphic ◽  
Dimorphic Gene Expression

scholarly journals STAT5 Signaling in Sexually Dimorphic Gene Expression and Growth Patterns

1999 ◽  
Vol 65 (4) ◽  
pp. 959-965 ◽  
Author(s):  
Helen W. Davey ◽  
Richard J. Wilkins ◽  
David J. Waxman
Keyword(s):  
Gene Expression ◽  
Growth Patterns ◽  
Sexually Dimorphic ◽  
Dimorphic Gene Expression

scholarly journals Mating Changes Sexually Dimorphic Gene Expression in the Seed Beetle Callosobruchus maculatus

2017 ◽  
Vol 9 (3) ◽  
pp. 677-699 ◽  
Author(s):  
Elina Immonen ◽  
Ahmed Sayadi ◽  
Helen Bayram ◽  
Göran Arnqvist
Keyword(s):  
Gene Expression ◽  
Callosobruchus Maculatus ◽  
Sexually Dimorphic ◽  
Seed Beetle ◽  
Dimorphic Gene Expression

Gene expression analysis of TFII-I modulated genes in mouse embryonic fibroblasts

2007 ◽  
Vol 308B (3) ◽  
pp. 225-235 ◽  
Author(s):  
Nyam-Osor Chimge ◽  
Ognoon Mungunsukh ◽  
Frank Ruddle ◽  
Dashzeveg Bayarsaihan
Keyword(s):  
Gene Expression ◽  
Expression Analysis ◽  
Gene Expression Analysis ◽  
Mouse Embryonic Fibroblasts ◽  
Embryonic Fibroblasts
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