Sensitivity of Multiple Myeloma to Imexon in the Human Tumor Cloning Assay

1994 ◽  
Vol 86 (3) ◽  
pp. 228-230 ◽  
Author(s):  
S. E. Salmon ◽  
E. M. Hersh
Keyword(s):  
Multiple Myeloma ◽  
Human Tumor ◽  
Cloning Assay ◽  
Human Tumor Cloning

Ultrastructural Correlations between Clonal Human Tumor Colonies and in Vivo Neoplasms

1982 ◽  
Vol 40 ◽  
pp. 210-211
Author(s):  
M.J. Murphy ◽  
R.R. Price ◽  
J.C. Sloman
Keyword(s):  
Cultured Cells ◽  
Human Tumor ◽  
Cell Type ◽  
Tumor Mass ◽  
Initial Cell ◽  
Cloning Assay ◽  
Human Tumor Cloning ◽  
The Relationship

The in vitro human tumor cloning assay originally described by Salmon and Hamburger has been applied recently to the investigation of differential anti-tumor drug sensitivities over a broad range of human neoplasms. A major problem in the acceptance of this technique has been the question of the relationship between the cultured cells and the original patient tumor, i.e., whether the colonies that develop derive from the neoplasm or from some other cell type within the initial cell population. A study of the ultrastructural morphology of the cultured cells vs. patient tumor has therefore been undertaken to resolve this question. Direct correlation was assured by division of a common tumor mass at surgical resection, one biopsy being fixed for TEM studies, the second being rapidly transported to the laboratory for culture.

In vitro activity of menogaril and N-demethylmenogaril in a human tumor cloning assay

1986 ◽  
Vol 22 (3) ◽  
pp. 245-249 ◽  
Author(s):  
P. Dodion ◽  
C. Sanders ◽  
W. Rombaut ◽  
M. Rozencweig ◽  
M.M. Kitt ◽  
...  
Keyword(s):  
Human Tumor ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Cloning Assay ◽  
Human Tumor Cloning

Phase II study of ametantrone in a human tumor cloning assay

1985 ◽  
Vol 21 (2) ◽  
pp. 195-198 ◽  
Author(s):  
Marcel Rozencweig ◽  
Charlotte Sanders ◽  
William Rombaut ◽  
Nadine Crespeigne ◽  
Yvon Kenis ◽  
...  
Keyword(s):  
Phase Ii ◽  
Phase Ii Study ◽  
Human Tumor ◽  
Cloning Assay ◽  
Human Tumor Cloning

In Vitro activity of the novel antitumor antibiotic fostriecin (CI-920) in a human tumor cloning assay

1986 ◽  
Vol 22 (8) ◽  
pp. 921-926 ◽  
Author(s):  
Werner Scheithauer ◽  
Daniel D. von Hoff ◽  
Gary M. Clark ◽  
Joan L. Shillis ◽  
Edward F. Elslager
Keyword(s):  
Human Tumor ◽  
Vitro Activity ◽  
Antitumor Antibiotic ◽  
The Novel ◽  
In Vitro Activity ◽  
Cloning Assay ◽  
Human Tumor Cloning

Activity of the multitargeted antifolate LY231514 in the human tumor cloning assay

1999 ◽  
Vol 44 (2) ◽  
pp. 105-110 ◽  
Author(s):  
Carolyn D. Britten ◽  
Elzbieta Izbicka ◽  
Susan Hilsenbeck ◽  
Richard Lawrence ◽  
Karen Davidson ◽  
...  
Keyword(s):  
Human Tumor ◽  
Cloning Assay ◽  
Human Tumor Cloning
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